Clinical Trials Browser

NCT06627270 2026-03-05

Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral Cancer

Phase 2 Recruiting

30 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Mouth Neoplasms

NCT06356597 2026-02-24

Tislelizumab With Fruquintinib, Metronidazole, in Mismatch Repair-proficient or Microsatellite Stability, Advanced Colorectal Cancer: a Multicenter, Single Arm, Clinical Trial

Phase 2 Active not recruiting

33 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT07429760 2026-02-24

Mechanical Bowel Preparation With or Without Oral Antibiotics in Left Sided Colorectal Cancer Surgery

Phase NA Enrolling by invitation

60 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT06616597 2026-02-19

Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients With Metastatic Prostate Cancer

Phase 2 Recruiting

58 enrolled

Genitourinary

Adenocarcinoma, Prostatic Neoplasms

NCT06728072 2026-02-09

Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer

Phase 2 Recruiting

97 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT04729322 2025-12-23

Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-responders

Phase 2 Active not recruiting

15 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT06126731 2025-11-24

Combination Study of Antibiotics With Enzalutamide (PROMIZE)

Phase 1/2 Recruiting

39 enrolled

Genitourinary

Metastatic Castration-Resistant Prostate Cancer (mCRPC)

NCT06569368 2025-10-06

Trial Utilizing Metronidazole to Optimize the Microbiome of Rectal Adenocarcinoma Undergoing Neoadjuvant Therapy

Phase 2 Recruiting

60 enrolled

Gastrointestinal

Rectal Neoplasms

NCT07144657 2025-08-27

GastricMALToma

Phase 2 Not yet recruiting

40 enrolled

Lymphoid

Lymphoma, B-Cell, Marginal Zone

NCT06793137 2025-01-29

Intestinal Microbiome Modulation With Antibiotics in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer

Phase 2 Recruiting

100 enrolled

Gastrointestinal

Rectal Neoplasms

NCT05784311 2024-10-21

SPARROW

Phase 4 Recruiting

344 enrolled

Gastrointestinal

Pancreatic Neoplasms, Surgical Wound Infection

NCT05462496 2024-10-15

Modulation of the Gut Microbiome With Pembrolizumab Following Chemotherapy in Resectable Pancreatic Cancer

Phase 2 Recruiting

25 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT04312360 2023-09-07

MEFO

Phase 2 Completed

28 enrolled

Gastrointestinal

Colonic Neoplasms

NCT02682485 2023-04-26

SES-DTA

Phase 2 Withdrawn

Gastrointestinal

Rectal Neoplasms, Anastomotic Leak

NCT03856671 2023-04-05

Prophylatic Effect Preoperative Antibiotics With Mechanical Bowel Preparation in SSIs

Phase NA Completed

309 enrolled

Gastrointestinal

Postoperative Complications, Surgical Wound Infection, Colorectal Neoplasms

NCT05720559 2023-02-09

Early Blocking Strategy for Metachronous Liver Metastasis of Colorectal Cancer Based on Pre-hepatic CTC Detection

Phase 2 Not yet recruiting

100 enrolled

Gastrointestinal

Preventive Effect of Quintuple Therapy on Metachronous Liver Metastases in Patients With Colorectal Cancer

NCT04273997 2021-09-22

Metronidazole Ointment in Non-healing Pilonidal Sinus Wounds

Phase 2 Unknown

80 enrolled

Pilonidal Sinus

NCT04264676 2020-11-25

Study of Oral Metronidazole on Postoperative Chemotherapy in Colorectal Cancer

Phase 2 Unknown

294 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT03891979 2020-06-26

Gut Microbiome Modulation to Enable Efficacy of Checkpoint-based Immunotherapy in Pancreatic Adenocarcinoma

Phase 4 Withdrawn

Gastrointestinal

Pancreatic Neoplasms

NCT03436719 2019-03-05

Antibiotic Prophylaxis in Rectal Cancer Surgery: Oral With Intravenous Versus Intravenous Antibiotics.

Phase NA Unknown

280 enrolled

Gastrointestinal

Rectal Neoplasms, Surgical Wound Infection

NCT01279252 2019-01-25

CLEAR

Phase 2 Completed

71 enrolled

LymphoidOther hematologic neoplasm

Leukemia, B-Cell

NCT03042091 2018-08-22

Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery

Phase EARLY_PHASE1 Unknown

224 enrolled

Gastrointestinal

Diverticulitis, Surgical Wound Infection, Colorectal Neoplasms, Inflammatory Bowel Diseases

NCT02388581 2016-03-25

First-line Antibiotic Therapy for Early-stage HP(+) Gastric Pure DLBCL

Phase 2 Unknown

30 enrolled

Lymphoid

Lymphoma, B-Cell, Marginal Zone

NCT00003151 2012-07-02

Antibiotic Therapy in Treating Patients With Low Grade Gastric Lymphoma

Phase 2 Completed

96 enrolled

LymphoidOther hematologic neoplasm

Lymphoma, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Marginal Zone

NCT00154440 2007-03-26

Helicobacter - Lymphoma - Radiation Part I: Eradication, Part II: Radiation

Phase 3 Unknown

200 enrolled

GastrointestinalLymphoid

Familial primary gastric lymphoma, Lymphoma, Lymphoma, Non-Hodgkin, Lymphoma, B-Cell, Marginal Zone