Clinical Trials Browser

Phase 2 × NVP-BKM120 × Clear all

NCT02159066 2024-03-05

LOGIC-2

Phase 2 Completed

158 enrolled 40 charts

Melanoma

NCT01397877 2023-09-06

ENDOPIK

Phase 2 Completed

Neoplasm Metastasis, Endometrial Neoplasms

NCT02340780 2023-08-22

Buparlisib in Patients With Relapsed and Refractory Chronic Lymphocytic Leukemia

Phase 2 Completed

14 enrolled 9 charts

LymphoidOther hematologic neoplasm

Leukemia, Lymphocytic, Chronic, B-Cell

NCT02000882 2022-02-07

STAR Cape+BKM120 MBC With Brain Met

Phase 2 Completed

10 enrolled 11 charts

Brain Neoplasms, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT01806649 2021-10-11

BKM120 in Esophageal Squamous Cell Carcinoma After Failure of First Line Chemotherapy

Phase 2 Terminated

Gastrointestinal

Esophageal Neoplasms

NCT01695473 2021-01-13

Neoadjuvant BKM120 in High-risk Prostate Cancer

Phase 2 Terminated

11 enrolled 8 charts

Prostatic Neoplasms

NCT01629615 2020-10-28

A Trial of BKM120 (a PI3K Inhibitor) in Patients With Triple Negative Metastatic Breast Cancer

Phase 2 Completed

50 enrolled 10 charts

Breast Neoplasms, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT01737450 2019-06-24

PIK-ORL

Phase 2 Completed

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence, Disease Progression

NCT01289041 2019-05-30

BKM120 as Second-line Therapy for Advanced Endometrial Cancer

Phase 2 Completed

70 enrolled 8 charts

Advanced Endometrial Cancer

NCT01487265 2019-03-06

Trial of Erlotinib and BKM120 in Patients With Advanced Non Small Cell Lung Cancer Previously Sensitive to Erlotinib

Phase 2 Completed

37 enrolled 10 charts

Carcinoma, Non-Small-Cell Lung

NCT02303041 2019-01-29

Pilot Study of Sonidegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell Carcinoma

Phase 2 Terminated

10 enrolled 11 charts

Basal Cell Nevus Syndrome, Carcinoma, Basal Cell, Skin Neoplasms

NCT01790932 2019-01-23

BKM120 For Triple Negative Breast Cancer

Phase 2 Completed

50 enrolled 8 charts

Breast Neoplasms, Neoplasm Metastasis

NCT01833169 2018-10-19

SIGNATURE

Phase 2 Completed

146 enrolled 17 charts

Other hematologic neoplasm

Neoplasms, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT01923168 2018-09-14

Study of Letrozole With or Without BYL719 or Buparlisib, for the Neoadjuvant Treatment of Postmenopausal Women

Phase 2 Completed

340 enrolled 39 charts

Breast Neoplasms

NCT02404844 2018-04-20

PIKTAM

Phase 2 Completed

Breast Neoplasms

NCT02301364 2017-10-19

Buparlisib (BKM120) In Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Recurrent/Refractory Secondary Central Nervous System Lymphoma (SCNSL)

Phase 2 Completed

4 enrolled 11 charts

Lymphoma, Recurrence

NCT01385293 2017-05-19

BKM120 in Metastatic Castration-resistant Prostate Cancer

Phase 2 Terminated

30 enrolled 11 charts

Neoplasm Metastasis, Prostatic Neoplasms

NCT02452294 2017-05-03

BUMPER

Phase 2 Unknown

Melanoma, Neoplasm Metastasis

NCT01830504 2016-10-05

BKM120

Phase 2 Unknown

Thyroid Neoplasms

NCT01297491 2016-03-11

BASALT-1

Phase 2 Completed

63 enrolled 12 charts

Carcinoma, Non-Small-Cell Lung

NCT02035124 2016-02-11

Cabazitaxel and BKM120 in Patients With Metastatic Castrate-Resistant Prostate Cancer (mCRPC) Previously Treated With Docetaxel

Phase 2 Withdrawn

Neoplasm Metastasis

NCT01501604 2015-09-17

BKM120 in Cancers With PIK3CA Activating Mutations

Phase 2 Withdrawn

BreastGastrointestinalThoracic

Breast Neoplasms, Lung Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT01953445 2014-12-08

Paclitaxel and BKM120 Before Surgery in Treating Patients With Stage II or III Estrogen Receptor-Positive and HER2-Negative Breast Cancer

Phase 2 Withdrawn

Breast Neoplasms

NCT01550380 2014-07-29

BKM120

Phase 2 Withdrawn

Endometrial Neoplasms