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Phase NA 1 Phase 2 1 Phase 1 1

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Completed 127 Active not recruiting 53 Terminated 50 Recruiting 34 Withdrawn 17 Not yet recruiting 11 Unknown 10 Suspended 2 Enrolling by invitation 1

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Interventional 1

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Cancer Type

Conditions

Glioblastoma 1 Astrocytoma 1

Interventions

toripalimab 1 ibrutinib 1 fludarabine 1 Spinal Puncture 1 Positron-Emission Tomography 1 Nivolumab 1 Magnetic Resonance Imaging 1 JNJ-64619178 1 JNJ-64264681 1 Dexamethasone 1 Deoxycholic Acid 1 Cyclophosphamide 1 Azacitidine 1

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NCT06896110 2025-06-26

Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma

University of Iowa

Phase 1 Enrolling by invitation

Astrocytoma, Glioblastoma

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