Clinical Trials Browser

Completed × Interventional × PEGPH20 × Clear all

NCT03281369 2025-12-15

A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)

Phase 1/2 Completed

Gastrointestinal

Esophageal Neoplasms

NCT03193190 2025-11-21

A Study of Multiple Immunotherapy-Based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pancreatic Cancer)

Phase 1/2 Completed

341 enrolled 28 charts

Gastrointestinal

Pancreatic Adenocarcinoma

NCT01959139 2024-02-09

S1313, PEGPH20 in Treating Patients With Newly Diagnosed Metastatic Pancreatic Cancer

Phase 1/2 Completed

126 enrolled 19 charts

Gastrointestinal

Metastatic Pancreatic Adenocarcinoma

NCT01839487 2020-07-20

PEGPH20 Plus Nab-Paclitaxel Plus Gemcitabine Compared With Nab-Paclitaxel Plus Gemcitabine in Participants With Stage IV Untreated Pancreatic Cancer

Phase 2 Completed

279 enrolled 19 charts

Gastrointestinal

Pancreatic Neoplasms, Carcinoma, Pancreatic Ductal

NCT02563548 2020-02-07

A Study of PEGylated Recombinant Human Hyaluronidase (PEGPH20) With Pembrolizumab in Participants With Selected Hyaluronan High Solid Tumors

Phase 1 Completed

56 enrolled 24 charts

Gastrointestinal

Stomach Neoplasms

NCT01453153 2018-11-30

Study of Gemcitabine + PEGPH20 vs Gemcitabine Alone in Stage IV Previously Untreated Pancreatic Cancer

Phase 1/2 Completed

28 enrolled 31 charts

Gastrointestinal

Neoplasms, Pancreatic Neoplasms

NCT01170897 2014-01-29

Study of PEGPH20 With Initial Dexamethasone Premedication Given Intravenously to Patients With Advanced Solid Tumors

Phase 1 Completed

Neoplasm Metastasis

NCT00834704 2013-03-26

PEG

Phase 1 Completed

Neoplasm Metastasis