Clinical Trials Browser

Phase 1 × Completed × Panobinostat × Clear all

NCT02032810 2023-01-20

Phase I of Histone Deacetylase (HDAC) Inhibitor Panobinostat With Ipilimumab With Unresectable III/IV Melanoma

Phase 1 Completed

17 enrolled 12 charts

Melanoma, Skin Neoplasms

NCT02890069 2023-01-11

A Study of PDR001 in Combination With LCL161, Everolimus or Panobinostat

Phase 1 Completed

BreastGastrointestinalGenitourinaryThoracic

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT01965353 2021-09-05

PanRVD

Phase 1 Completed

Multiple Myeloma

NCT00503451 2020-12-19

A Study to Investigate the Effects of Ketoconazole on LBH589 in Patients With Advanced Solid Tumors

Phase 1 Completed

Lymphoma, Lymphoma, Non-Hodgkin, Neoplasms

NCT00532675 2020-12-19

Safety Study of LBH589 When Given in Combination With Lenalidomide and Dexamethasone in Adult Patients With Multiple Myeloma.

Phase 1 Completed

Multiple Myeloma, Neoplasms, Plasma Cell

NCT00570284 2020-12-19

A Study to Investigate the Effect of Food on Oral LBH589 Absorption in Patients With Advanced Solid Tumors

Phase 1 Completed

Neoplasms

NCT00739414 2020-12-19

Dose-escalating Study of LBH589 in Adult Patients With Advanced Solid Tumors

Phase 1 Completed

Neoplasms

NCT00788931 2020-12-19

A Trial l of Panobinostat Given in Combination With Trastuzumab and Paclitaxel in Adult Female Patients With HER2 Positive Metastatic Breast Cancer

Phase 1 Completed

Breast Neoplasms

NCT00997399 2020-12-19

Study to Evaluate Panobinostat (DACi) Pharmacokinetics and Safety in Solid Tumors and Varying Renal Function

Phase 1 Completed

Other solid neoplasm

Advanced Solid Tumors

NCT01242774 2020-12-19

Safety & Efficacy Study of Oral Panobinostat (LBH589) With Chemotherapy in Patients < 65 Years Old With Acute Myeloid Leukemia (AML)

Phase 1 Completed

Other hematologic neoplasm

Chromosome Aberrations, Leukemia, Myeloid, Acute

NCT01613976 2020-12-19

A Phase Ib Study of Panobinostat (LBH589) in Combination With 5-Azacitidine for Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML) or Acute Myeloid Leukemia (AML) Patients

Phase 1 Completed

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT01463046 2019-04-22

Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome

Phase 1 Completed

Other hematologic neoplasm

Leukemia, Leukemia, Myeloid, Acute

NCT01440582 2019-03-04

Combination Therapy of Lenalidomide/Bortezomib/Dexamethasone and Panobinostat in Transplant Eligible New Diagnosed Multiple Myeloma (MM) Patients

Phase 1 Completed

Multiple Myeloma, Neoplasms, Plasma Cell

NCT01549431 2019-01-16

Study of the Combination of Panobinostat & Carfilzomib in Patients With Relapsed &/or Refractory Multiple Myeloma

Phase 1 Completed

Multiple Myeloma

NCT01336842 2018-01-09

Study of Cisplatin and Pemetrexed in Combination With Panobinostat in Solid Tumors

Phase 1 Completed

Carcinoma, Non-Small-Cell Lung

NCT00878904 2017-03-24

Panobinostat and Epirubicin in Treating Patients With Metastatic Malignant Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT01005797 2017-03-03

Study of Panobinostat in Combination With Sorafenib in Kidney, Soft Tissue or Lung Cancers

Phase 1 Completed

GenitourinarySarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Kidney Neoplasms, Sarcoma

NCT01321346 2015-11-24

A Study Of Panobinostat In Children With Refractory Hematologic Malignancies

Phase 1 Completed

LymphoidOther hematologic neoplasm

Hodgkin Disease, Leukemia, Leukemia, Myeloid, Lymphoma, Lymphoma, Non-Hodgkin, Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00632489 2015-06-08

LBH589 in Combination With Capecitabine Plus/Minus (±) Lapatinib in Breast Cancer Patients

Phase 1 Completed

20 enrolled 5 charts

Breast Neoplasms, Neoplasms

NCT01504776 2014-09-19

BUS48T

Phase 1 Completed

Lymphoma, Lymphoma, Mantle-Cell

NCT00686218 2014-08-15

Panobinostat (LBH589) and Imatinib Mesylate in Treating Patients With Previously Treated Chronic Phase Chronic Myelogenous Leukemia

Phase 1 Completed

Other hematologic neoplasm

Leukemia, Leukemia, Myeloid, Chronic-Phase

NCT00962507 2013-02-15

Panobinostat and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

Phase 1 Completed

DermatologicLymphoidOther hematologic neoplasmPlasma cell

Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Lymphoma, Extranodal NK-T-Cell

NCT01055795 2012-12-24

BEL

Phase 1 Completed

Other solid neoplasm

Advanced Solid Tumors

NCT00412997 2012-11-27

LBH589 in Adult Patients With Advanced Solid Tumors or Cutaneous T-cell Lymphoma

Phase 1 Completed

DermatologicLymphoid

Neoplasms, Lymphoma, T-Cell, Cutaneous

NCT00472368 2012-05-01

A Study to Determine the Absorption, Distribution, Metabolism, and Excretion of LBH589

Phase 1 Completed

Lymphoma

NCT00556088 2010-12-30

LBH589, Paclitaxel, Carboplatin +/- Bevacizumab for Solid Tumors

Phase 1 Completed

Other solid neoplasm

Solid Tumors