Panobinostat, Gemcitabine Hydrochloride, Busulfan, and Melphalan Before Stem Cell Transplant in Treating Patients With Refractory or Relapsed Multiple Myeloma
Phase 2 Completed
83 enrolled 11 charts
PANORAMA_3
Phase 2 Completed
248 enrolled 28 charts
PBTC-047
Phase 1 Completed
53 enrolled 25 charts
Panobinostat and Carfilzomib in Treating Participants With Relapsed or Refractory Multiple Myeloma
Phase 1 Completed
63 enrolled
A Phase II Study of Oral Panobinostat (LBH589) and Rituximab to Treat Diffuse Large B Cell Lymphoma (DLBCL)
Phase 2 Completed
42 enrolled
Phase I of Histone Deacetylase (HDAC) Inhibitor Panobinostat With Ipilimumab With Unresectable III/IV Melanoma
Phase 1 Completed
17 enrolled 12 charts
A Study of PDR001 in Combination With LCL161, Everolimus or Panobinostat
Phase 1 Completed
298 enrolled
Panobinostat (LBH589): Multiple Myeloma - Autologous Hematopoietic Cell Transplantation (HCT)
Phase 2 Completed
30 enrolled 12 charts
Panobinostat in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
Phase 2 Completed
41 enrolled 8 charts
VEG VCA1
Phase 2 Completed
30 enrolled
LBH589 Treatment for Refractory Clear Cell Renal Carcinoma
Phase 2 Completed
20 enrolled 7 charts
PanRVD
Phase 1 Completed
21 enrolled
Phase II Study of Oral Panobinostat in Adult Participants With Relapsed/Refractory Classical Hodgkin's Lymphoma
Phase 2 Completed
129 enrolled 16 charts
Efficacy and Safety Study of Panobinostat in Participants With Metastatic Hormone Refractory Prostate Cancer
Phase 2 Completed
35 enrolled 8 charts
LBH589 in Relapsed or Relapsed and Refractory Waldenstrom's Macroglobulinemia
Phase 2 Completed
39 enrolled 13 charts
Panobinostat Plus Ifosfamide, Carboplatin, and Etoposide (ICE) Compared With ICE For Relapsed Hodgkin Lymphoma
Phase 1/2 Completed
62 enrolled 13 charts
A Study to Investigate the Effects of Ketoconazole on LBH589 in Patients With Advanced Solid Tumors
Phase 1 Completed
14 enrolled
Safety Study of LBH589 When Given in Combination With Bortezomib in Adult Patients With Multiple Myeloma
Phase 1 Completed
62 enrolled
Safety Study of LBH589 When Given in Combination With Lenalidomide and Dexamethasone in Adult Patients With Multiple Myeloma.
Phase 1 Completed
46 enrolled
Pharmacokinetic, Safety, and Efficacy Effects of Oral LBH589 on Dextromethorphan in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer or Malignant Pleural Mesothelioma
Phase 1 Completed
18 enrolled
A Study to Investigate the Effect of Food on Oral LBH589 Absorption in Patients With Advanced Solid Tumors
Phase 1 Completed
36 enrolled
A Dose Finding Study With I.V. Panobinostat (LBH589), Docetaxel, and Prednisone in Patients With Hormone Refractory Prostate Cancer
Phase 1 Completed
44 enrolled
Dose-escalating Study of LBH589 in Adult Patients With Advanced Solid Tumors
Phase 1 Completed
14 enrolled
A Trial l of Panobinostat Given in Combination With Trastuzumab and Paclitaxel in Adult Female Patients With HER2 Positive Metastatic Breast Cancer
Phase 1 Completed
15 enrolled
Study to Evaluate Panobinostat (DACi) Pharmacokinetics and Safety in Solid Tumors and Varying Renal Function
Phase 1 Completed
37 enrolled
Pharmacokinetics and Safety of Panobinostat in Patients With Advanced Solid Tumors and Various Degrees of Hepatic Function
Phase 1 Completed
25 enrolled
Safety & Efficacy Study of Oral Panobinostat (LBH589) With Chemotherapy in Patients < 65 Years Old With Acute Myeloid Leukemia (AML)
Phase 1 Completed
46 enrolled
A Phase Ib Study of Panobinostat (LBH589) in Combination With 5-Azacitidine for Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML) or Acute Myeloid Leukemia (AML) Patients
Phase 1 Completed
10 enrolled
A Phase Ib/IIb, Open-label, Multi-center, Study of Oral Panobinostat Administered With 5-Azacitidine (in Adult Patients With Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML).
Phase 1/2 Completed
113 enrolled 21 charts
PANORAMA-1
Phase 3 Completed
767 enrolled 17 charts
Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma
Phase 1/2 Completed
124 enrolled 10 charts
MLN9708 (Ixazomib) in Combination With Panobinostat and Dexamethasone in Multiple Myeloma
Phase 1/2 Completed
16 enrolled 12 charts
Study to Allow Access to Single Agent Panobinostat for Patients Who Are on s.a. Panobinostat Treatment in a Novartis-sponsored Study and Continue to Benefit From the Treatment as Judged by the Investigator
Phase 2 Completed
9 enrolled 8 charts
Trial of LBH589 in Metastatic Thyroid Cancer
Phase 2 Completed
13 enrolled 11 charts
FIL_PanAL10
Phase 2 Completed
35 enrolled 10 charts
Study of Panobinostat in Combination With Bortezomib and Dexamethasone in Japanese Patients With Relapsed/Refractory Multiple Myeloma
Phase 2 Completed
31 enrolled 19 charts
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome
Phase 1 Completed
29 enrolled
Combination Therapy of Lenalidomide/Bortezomib/Dexamethasone and Panobinostat in Transplant Eligible New Diagnosed Multiple Myeloma (MM) Patients
Phase 1 Completed
77 enrolled
Study of the Combination of Panobinostat & Carfilzomib in Patients With Relapsed &/or Refractory Multiple Myeloma
Phase 1 Completed
32 enrolled
PANOBIDARA
Phase 1/2 Completed
46 enrolled
Phase II, Single-Center, Oral Panobinostat in Combination With Lenalidomide and Dexamethasone in Multiple Myeloma (MM)
Phase 2 Completed
32 enrolled 21 charts
Study of Cisplatin and Pemetrexed in Combination With Panobinostat in Solid Tumors
Phase 1 Completed
23 enrolled
MACS1271
Phase 2 Completed
55 enrolled 11 charts
A Phase II Trial of Panobinostat and Lenalidomide in Patients With Relapsed or Refractory Hodgkin's Lymphoma
Phase 2 Completed
24 enrolled 7 charts
Panobinostat and Letrozole in Treating Patients With Metastatic Breast Cancer
Phase 1/2 Completed
28 enrolled 13 charts
Panobinostat and Epirubicin in Treating Patients With Metastatic Malignant Solid Tumors
Phase 1 Completed
40 enrolled
LBH589 and Bevacizumab in Patients With Recurrent High Grade Glioma
Phase 1/2 Completed
51 enrolled 18 charts
Study of Panobinostat in Combination With Sorafenib in Kidney, Soft Tissue or Lung Cancers
Phase 1 Completed
38 enrolled
Efficacy and Safety of Panobinostat (LBH589) in Patients With Refractory de Novo or Secondary Acute Myelogenous Leukemia (AML)
Phase 2 Completed
59 enrolled 7 charts
LBH589 Plus Decitabine for Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukemia (AML)
Phase 1/2 Completed
52 enrolled 18 charts