Clinical Trials

Carcinoma, Non-Small-Cell Lung

NCT03380468 2023-07-20

ECTOP-1004

Phase 2/3 Unknown

300 enrolled

Adenocarcinoma of Lung, Lung Neoplasms

NCT05527808 2023-06-08

A Single-arm Exploratory Study of Neoadjuvant Therapy

Phase NA Unknown

28 enrolled

Adenocarcinoma of Lung

NCT05810350 2023-04-13

Aumolertinib Combined Intrathecal Chemotherapy for Leptomeningeal Metastasis From EGFR-Mutated NSCLC and Prognostic Value of Dynamic Changes in cfDNA Profiles

40 enrolled

CNSThoracic

Carcinoma, Non-Small-Cell Lung, Meningeal Carcinomatosis

NCT03991403 2023-04-03

Study of Atezolizumab Combination Carboplatin + Paclitaxel + Bevacizumab in EGRF Mutation or ALK Translocation NSCLC

228 enrolled

Carcinoma, Non-Small-Cell Lung

NCT01656551 2023-03-24

MILES-4

232 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04396457 2023-03-23

Pembrolizumab Plus Pemetrexed for Elderly Patients With Non-Sq NSCLC With PD-L1 < 50%: CJLSG1901

50 enrolled

Lung Neoplasms

NCT04638582 2023-03-22

Pembrolizumab as Neoadjuvant Therapy for Resectable Stage IA3 to IIA Non-Small Cell Lung Cancer (NSCLC)

44 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05648071 2022-12-13

SPBPDC

60 enrolled

Advanced Non-squamous Non-Small-Cell Lung Cancer

NCT03574402 2022-12-06

TRUMP

400 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04211090 2022-11-16

CAP-BRAIN

45 enrolled

CNS

Brain Neoplasms

NCT05574998 2022-10-12

FTANLCNDG

100 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05305885 2022-09-30

Intra-pemetrexed Alone or Combined With Concurrent Radiotherapy for Leptomeningeal Metastasis

Phase NA Unknown

100 enrolled

CNS

Meningeal Carcinomatosis

NCT04683965 2022-08-02

Pemetrexed and TAS-102 in Combination With Bevacizumab in Refractory Colorectal Cancer

27 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT05477615 2022-07-28

Lazertinib/Pemetrexed/Carboplatin After Osimertinib Failure in NSCLC With Brain Metastases

28 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05458726 2022-07-26

Correlation Between Efficacy of Osimertinib and EGFR T790M Status and Ratio Via ddPCR in NSCLC

80 enrolled

Phase EARLY_PHASE1 Unknown

Carcinoma, Non-Small-Cell Lung

NCT05459441 2022-07-15

Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases

CNS

Brain Neoplasms, Glioma

NCT04459611 2022-07-12

neoSCORE

60 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05448781 2022-07-07

Recombinant Human Angioendostatin /PD-1 Mab Combined With First-line Chemotherapy in the Treatment of Driver Gene Negative Advanced NSCLC

38 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05430802 2022-06-24

Neoadjuvant Furmonertinib and Cisplatin/Pemetrexed as in EGFR Mutated Stage IIIA-IIIB Resectable NSCLC (FORESEE)

40 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02588781 2022-06-15

Pemetrexed Alone as Salvage Treatment in Metastatic Colorectal Cancer Patients Who Were Failed After Standard Chemotherapy: A Phase II Single Arm Prospective Study

23 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT03110484 2022-06-15

Pemetrexed in Combination With Erlotinib as a Salvage Treatment in Patients With Metastatic Biliary Tract Cancer (BTC) Who Failed Gemcitabine Containing Chemotherapy: A Phase II Single Arm Prospective Study

44 enrolled

Gastrointestinal

Biliary Tract Neoplasms

NCT05394233 2022-05-27

Tislelizumab +Bevacizumab+pc for Untreated EGFR+ and High PD-L1 Non-squamous NSCLC

20 enrolled

Non-squamous Non-small Cell Lung Cancer

NCT01951469 2022-03-08

Gefitinib With or Without Chemotherapy in Brain Metastases From Non-small Cell Lung Cancer

160 enrolled

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT05209256 2022-01-26

Alflutinib Versus Alflutinib Plus Chemotherapy for NSCLC

Phase 2/3 Unknown

90 enrolled

NSCLC

NCT02743923 2021-12-21

Cisplatin-Pemetrexed Compared With Carboplatin-Paclitaxel-Bevacizumab in KRAS Mutated Non-small Cell Lung Cancer

203 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04989322 2021-12-08

Pembrolizumab, Lenvatinib and Chemotherapy After TKIs in NSCLC

46 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04405674 2021-11-22

Tislelizumab Combined With Chemotherapy With or Without Bevacizumab in TKI-Resistant EGFR-Mutated Non-squamous NSCLC

120 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03830411 2021-11-08

A Study of Sintilimab Compared With Docetaxel or Pemetrexed as Second-line Treatment for Patients With Stage IV Nonsquamous Non-small Cell Lung Cancer After Failure With Platinum-Containing Chemotherapy

76 enrolled

Nonsquamous Non-Small Cell Lung Cancer

NCT03863483 2021-11-08

A Study of Sintilimab or Placebo in Combination With Chemotherapy as Second-line Treatment for Patients With Stage IV Nonsquamous Non-small Cell Lung Cancer With Wild-type EGFR After Failure With Platinum-Containing Chemotherapy.

70 enrolled

Nonsquamous Non-Small Cell Lung Cancer

NCT04943029 2021-09-02

NEOSUN

Carcinoma, Non-Small-Cell Lung

NCT04586465 2021-08-24

DYNAPET

23 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04465942 2021-08-23

Immunotherapy in Lung Cancer: Treatment After IO Cessation.

Unknown

300 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04846452 2021-08-12

Sintilimab, Anlotinib Hydrochloride and Platinum-Containing Dual-Agent Chemotherapy in NSCLC

40 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04982549 2021-08-06

A Study to Evaluate the Safety of Concurrent Durvalumab With CRT Followed by Durvalumab for Chinese Unresectable Stage III NSCLC

35 enrolled

Unresectable Stage III NSCLC

NCT04768075 2021-02-24

Camrelizumab Combined With SRT/WBRT and Chemotherapy in Patients With Brain Metastases of Driven Gene-negative NSCLC

200 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04713761 2021-01-26

Neoadjuvant Toripalimab Combined With Chemotherapy in the Treatment of Malignant Pleural Mesothelioma

Other solid neoplasmThoracic

15 enrolled

Mesothelioma, Malignant

NCT04706949 2021-01-13

Pyrotinib Combined With Pemetrexed Plus Carboplatin in the First-line Treatment

26 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04530227 2020-11-13

Camrelizumab With Chemotherapy in Adults With Medically Inoperable Early Stage NSCLC

Parkinson Disease 4, Autosomal Dominant Lewy Body

NCT04500704 2020-08-05

ACROSS1

166 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04500717 2020-08-05

ACROSS2

460 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04316351 2020-07-23

Efficacy and Safety of Toripalimab (JS001) Combined With Pemetrexed and Anlotinib for Patients With T790M Positive Non-Small Cell Lung Cancer After Osimertinib Resistance

60 enrolled

IIIb/IV NSCLC With T790M Positive Mutations Failed to Osimertinib Therapy

NCT04470076 2020-07-14

Neoafa

Carcinoma, Non-Small-Cell Lung

NCT03987867 2020-07-07

Study of Autologous CIK Cell Immunotherapy Combination With PD-1 Inhibitor and Chemotherapy in the Advanced NSCLC

Phase 1 Unknown

Carcinoma, Non-Small-Cell Lung

NCT04455594 2020-07-02

ANSWER

168 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04115410 2020-05-28

PD-1 Immune Checkpoint Inhibitors and Immune-Related Adverse Events: a Cohort Study

Unknown

4,724 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03706287 2020-04-06

Efficacy and Safety of Anlotinib Plus Platinum Plus Pemetrexed in T790M-negative NSCLC

Phase 1/2 Unknown

62 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02076477 2020-03-17

OITROLC

420 enrolled

Carcinoma, Non-Small-Cell Lung

NCT00276783 2020-03-05

Pemetrexed Disodium in Treating Patients With Recurrent Malignant Gliomas, Primary CNS Lymphoma, or Brain Metastases

31 enrolled

CNSLymphoidSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Lymphoma, Neoplasm Metastasis, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT02725918 2020-02-12

Pemetrexed vs Pemetrexed Plus Cisplatin in EGFR-mutant NSCLC Patients After First Line EGFR-TKIs Failure

150 enrolled