Clinical Trials Browser

Interventional × Photochemotherapy × Clear all

NCT07241585 2026-03-17

Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)

Phase NA Not yet recruiting

Carcinoma, Basal Cell, Carcinoma, Squamous Cell

NCT05923060 2026-02-20

Imaging Techniques to Monitor Photosensitizer and sO2 Levels During Photodynamic Therapy of Actinic Keratoses

Phase 2 Completed

Keratosis, Actinic

NCT06943664 2026-02-18

Photoimmunotherapy With ASP-1929 and Cemiplimab for the Treatment of Refractory, Inoperable, and Metastatic Stage IIIB-IV Non-small Cell Lung Cancer

Phase 2 Not yet recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02662504 2026-02-05

MesoPDT

Phase 2 Completed

Other solid neoplasmThoracic

Mesothelioma, Malignant, Mesothelioma

NCT04836429 2026-02-04

Photodynamic Therapy to Amplify the Response to Immunotherapy in Patients With Non-small Cell Lung Cancer With Pleural Disease

Phase 1 Terminated

Carcinoma, Non-Small-Cell Lung, Pleural Diseases

NCT06381154 2026-01-30

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer

Phase 2 Recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT02153229 2025-12-26

MPM-PDT

Phase 2 Active not recruiting

Other solid neoplasmThoracic

Epitheliod Malignant Pleural Mesothelioma

NCT06807359 2025-12-18

Photodynamic Therapy of Primary Localized Prostate Cancer With the SpectraCure P18 System

Phase 1/2 Recruiting

Prostatic Neoplasms

NCT03033225 2025-07-30

Ultrasound-Guided Verteporfin Photodynamic Therapy for the Treatment of Unresectable Solid Pancreatic Tumors or Advanced Pancreatic Cancer, VERTPAC-02 Study

Phase 2 Completed

13 enrolled 6 charts

Gastrointestinal

Pancreatic Neoplasms

NCT03678350 2025-05-11

Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery

Phase 1 Active not recruiting

Other solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Pleural Diseases

NCT02728388 2025-05-08

Photodynamic Therapy for Benign Dermal Neurofibromas- Phase II

Phase 2 Recruiting

Neurofibroma, Neurofibromatosis 1

NCT04429308 2025-05-08

PDT vs Peels for Treatment of Actinic Keratoses

Phase 2 Not yet recruiting

Keratosis, Actinic

NCT00472459 2025-04-18

Photodynamic Therapy (PDT) With Metvix® 160 Milligrams/Gram Cream in Organ Transplant Participants With Non-melanoma Skin Cancer

Phase 3 Completed

82 enrolled 20 charts

Bowen's Disease, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Warts, Keratosis, Actinic

NCT05551299 2025-03-27

CARP

Phase 4 Recruiting

Gastrointestinal

Bile Duct Neoplasms, Klatskin Tumor

NCT06745999 2024-12-24

Cryotherapy in Combination with Red Light PDT for Actinic Keratosis of Full Face

Phase 4 Recruiting

Keratosis, Actinic

NCT06712381 2024-12-02

Carac & PDT Combination in the Treatment Of Actinic Keratoses

Phase 1/2 Completed

Keratosis, Actinic

NCT03467789 2024-10-17

Vitamin D as a Nutritional Neoadjuvant During Photodynamic Therapy of Basal Cell Carcinoma

Phase 1 Completed

Basal Cell Nevus Syndrome, Carcinoma, Basal Cell

NCT06437288 2024-09-23

Hematoporphyrin Photodynamic Therapy for Esophageal Cancer

Phase 4 Not yet recruiting

Gastrointestinal

Esophageal Neoplasms

NCT01966120 2023-07-28

Safety and Efficacy Study for the Field-directed Treatment of Actinic Keratosis (AK) With Photodynamic Therapy (PDT)

Phase 3 Completed

87 enrolled 21 charts

Keratosis, Actinic

NCT03281811 2023-01-05

Photodynamic Therapy in Treating Patients With Refractory Mycosis Fungoides

Phase EARLY_PHASE1 Completed

Mycosis Fungoides

NCT05386056 2022-11-28

Pembrolizumab and Photodynamic Therapy in Previously Treated Metastatic Esophageal Squamous Cell Carcinoma

Phase 2 Unknown

Gastrointestinal

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Squamous Cell Carcinoma

NCT00784108 2022-11-01

Optimizing Photodynamic Therapy of Cutaneous Neoplastic Diseases Via Structured Illumination and Real-time Dosimetry.

Phase 1 Completed

Signs and Symptoms, Skin Neoplasms

NCT05488860 2022-08-05

Piezoelectric Drived Microneedling in Treating Refractory Skin Diseases

Phase NA Unknown

Keloid, Skin Diseases, Skin Neoplasms, Warts, Cicatrix, Hypertrophic

NCT00470496 2022-07-25

Photodynamic Therapy Using HPPH in Treating Patients Undergoing Surgery for Primary or Recurrent Head and Neck Cancer

Phase 1 Completed

CNSEndocrineHead & Neck

Squamous Cell Carcinoma of Head and Neck, Thyroid Cancer, Papillary, Salivary Gland Neoplasms, Thyroid Neoplasms, Adenocarcinoma, Follicular, Esthesioneuroblastoma, Olfactory

NCT01854684 2022-07-22

Photodynamic Therapy During Surgery in Treating Patients With Non-small Cell Lung Cancer That Can Be Removed by Surgery

Phase 1 Completed

Carcinoma, Non-Small-Cell Lung

NCT04140292 2022-06-24

Vitamin D Supplementation as a Neoadjuvant for Photodynamic Therapy of Actinic Keratoses

Phase 2 Completed

75 enrolled 8 charts

Keratosis, Actinic

NCT03090412 2022-06-02

Photodynamic Therapy With HPPH Compared to Standard of Care Surgery in Treating Patients With Oral Cavity Cancer

Phase 2 Terminated

2 enrolled 11 charts

Squamous Cell Carcinoma of Head and Neck

NCT00558688 2021-12-06

A Photodynamic Therapy for Treatment of Actinic Keratoses

Phase NA Completed

Keratosis, Actinic

NCT00756288 2021-12-06

Photo-therapy With a Topical Retinoid Versus Photo-therapy Alone for Actinic Keratoses

Phase NA Withdrawn

Keratosis, Actinic

NCT04301999 2021-09-01

Clinical Effect and Safety of PDT and RFA for Unresectable EHCC

Phase NA Completed

Gastrointestinal

Cholangiocarcinoma

NCT02157623 2020-07-30

Blue vs Red Light During Levulan Based Photodynamic Therapy in Patients With Basal Cell Nevus Syndrome

Phase NA Completed

3 enrolled 7 charts

Basal Cell Nevus Syndrome

NCT03564054 2019-12-18

Trial of Photodynamic Therapy Versus Argon Plasma Coagulation for Lung Cancer With Endobronchial Obstruction

Phase NA Terminated

Carcinoma, Non-Small-Cell Lung

NCT01800838 2019-05-16

Silicon Phthalocyanine 4 and Photodynamic Therapy in Stage IA-IIA Cutaneous T-Cell Non-Hodgkin Lymphoma

Phase 1 Completed

11 enrolled 10 charts

DermatologicLymphoid

Mycosis Fungoides, Sezary Syndrome, Lymphoma, T-Cell, Cutaneous

NCT02106559 2019-03-21

Photodynamic Therapy During Surgery in Treating Patients With Pleural Malignancy

Phase NA Withdrawn

Other solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT02702700 2019-03-20

PDT-lipo

Phase 1 Terminated

Pleural Effusion, Malignant

NCT01682746 2019-02-25

Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors

Phase 1 Completed

CNSEndocrineSarcoma

Astrocytoma, Brain Neoplasms, Chordoma, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pituitary Neoplasms, Germinoma, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Optic Nerve Glioma

NCT03346304 2019-02-01

PEARL

Phase 2/3 Withdrawn

Lung Neoplasms

NCT01770132 2018-12-13

Ultrasound-Guided Photodynamic Therapy With Photofrin & Gemcitabine for Patients With Locally Advanced Pancreatic Cancer

Phase 1 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT03053635 2018-08-20

Intravesical Photodynamic Therapy (PDT) in BCG Refractory High-Risk Non-muscle Invasive Bladder Cancer (NMIBC) Patients

Phase 1 Completed

Non-Muscle Invasive Bladder Neoplasms, Carcinoma, Transitional Cell

NCT00587600 2017-11-22

BIOBAR

Phase 2/3 Completed

Gastrointestinal

Barrett Esophagus

NCT02068157 2017-10-11

Interstitial Photodynamic Therapy in Treating Patients With Recurrent Head and Neck Cancer

Phase 2 Terminated

3 enrolled 8 charts

Lymphoid Interstitial Pneumonia, Squamous Cell Carcinoma of Head and Neck, Tongue Neoplasms

NCT02628236 2017-09-18

Maximal Use Systemic Exposure Study of Levulan Kerastick (MUSE 2)

Phase 2 Completed

14 enrolled 39 charts

Keratosis, Actinic

NCT01538901 2017-09-12

AKtransplant

Phase 4 Terminated

Keratosis, Actinic

NCT01755013 2017-02-20

Photodynamic Therapy (PDT) for Palliation of Cholangiocarcinoma

Phase 2/3 Unknown

Gastrointestinal

Bile Duct Neoplasms, Cholangiocarcinoma

NCT02281136 2017-01-13

Maximal Use Systemic Exposure (MUSE) Study of Levulan Kerastick

Phase 2 Completed

29 enrolled 34 charts

Keratosis, Actinic

NCT01522677 2016-12-01

A Study of Neoadjuvant Photodynamic Immunomodulation for Colon Cancer

Phase 1/2 Withdrawn

Gastrointestinal

Colonic Neoplasms, Photosensitivity Disorders

NCT02119728 2016-04-21

Photodynamic Therapy With HPPH in Treating Patients With Squamous Cell Carcinoma of the Oral Cavity

Phase 2 Withdrawn

Squamous Cell Carcinoma of Head and Neck

NCT00217087 2015-12-24

Endoscopic Therapy of Early Cancer in Barretts Esophagus

Phase 2 Completed

73 enrolled 9 charts

Gastrointestinal

Barrett Esophagus

NCT00907413 2015-06-03

PDT

Phase 3 Terminated

Gastrointestinal

Neoplasms, Cholangiocarcinoma

NCT01203878 2014-12-08

Treatment of Actinic Keratoses of the Face With Imiquimod 3.75% Cream Followed by Photodynamic Therapy

Phase 4 Terminated

21 enrolled 10 charts

Keratosis, Actinic