Clinical Trials Browser

Phase 1/2 × Radiosurgery × Clear all

NCT03604978 2026-03-18

Nivolumab and Multi-fraction Stereotactic Radiosurgery With or Without Ipilimumab in Treating Patients With Recurrent Grade II-III Meningioma

Phase 1/2 Active not recruiting

Meningioma

NCT05987644 2026-03-09

DURABLE

Phase 1/2 Recruiting

Brain Neoplasms, Lung Neoplasms

NCT05789589 2026-03-04

ADORATION

Phase 1/2 Recruiting

Brain Neoplasms, Neoplasm Metastasis, Neoplasms

NCT04785287 2026-03-03

Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Malignancies

Phase 1/2 Terminated

EndocrineGastrointestinalThoracic

Adrenal Gland Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT04923542 2026-02-06

Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases

Phase 1/2 Recruiting

Brain Neoplasms

NCT04711824 2025-12-23

SOLARA

Phase 1/2 Recruiting

Brain Neoplasms, Breast Neoplasms

NCT06238921 2025-12-05

Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases

Phase 1/2 Recruiting

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT03767582 2025-12-03

Trial of Neoadjuvant and Adjuvant Nivolumab and BMS-813160 With or Without GVAX for Locally Advanced Pancreatic Ductal Adenocarcinomas.

Phase 1/2 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT04021043 2025-12-03

BMS-986156, Ipilimumab, and Nivolumab With or Without Stereotactic Body Radiation Therapy in Treating Patients With Advanced or Metastatic Lung/Chest or Liver Cancers

Phase 1/2 Completed

51 enrolled 16 charts

Neoplasm Metastasis

NCT06439888 2025-12-01

LySATRA

Phase 1/2 Recruiting

Other solid neoplasm

Oligometastatic Disease

NCT02696993 2025-11-10

Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer

Phase 1/2 Active not recruiting

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT00492817 2025-10-24

Evaluation of Single Session Stereotactic Body Radiotherapy

Phase 1/2 Completed

71 enrolled 10 charts

Spinal Neoplasms

NCT02444741 2025-10-09

Pembrolizumab and Stereotactic Body Radiation Therapy or Non-Stereotactic Wide-Field Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer

Phase 1/2 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT04977375 2025-09-03

Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma

Phase 1/2 Recruiting

Brain Neoplasms, Glioblastoma, Glioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT03383302 2025-08-01

STILE

Phase 1/2 Completed

Carcinoma, Non-Small-Cell Lung

NCT01891318 2025-07-02

Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

Phase 1/2 Recruiting

Brain Neoplasms

NCT04194554 2025-06-04

ASCLEPIuS

Phase 1/2 Active not recruiting

Prostatic Neoplasms

NCT06940921 2025-04-27

SBRT-LDRT-Cadonilimab for Advanced Gastric, Colorectal and Ovarian Cancers With Peritoneal Metastases

Phase 1/2 Active not recruiting

GastrointestinalGynecologic

Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT03508752 2025-04-16

Neurocognitive Decline in Patients With Brain Metastases

Phase 1/2 Recruiting

Brain Neoplasms

NCT03169790 2025-02-24

QUILT-3.052: NANT Non-Hodgkin Lymphoma (NHL) Vaccine: Combination Immunotherapy in Subjects With Relapsed CD20-positive NHL

Phase 1/2 Withdrawn

Lymphoma, Non-Hodgkin

NCT03167164 2025-02-21

QUILT-3.045: NANT Merkel Cell Carcinoma (MCC) Vaccine: Combination Immunotherapy in Subjects With MCC Who Have Progressed on or After PD-L1 Therapy

Phase 1/2 Withdrawn

Carcinoma, Merkel Cell

NCT03167177 2025-02-21

QUILT-3.046: NANT Melanoma Vaccine: Combination Immunotherapy in Subjects With Melanoma Who Have Progressed On or After Chemotherapy and PD-1/PD-L1 Therapy

Phase 1/2 Withdrawn

Melanoma

NCT03169738 2025-02-21

QUILT-3.044: NANT Non-small Cell Lung Cancer (NSCLC) Vaccine: Combination Immunotherapy in Subjects With NSCLC Who Have Progressed After Treatment With PD-1/PD-L1 Inhibitors

Phase 1/2 Withdrawn

Carcinoma, Non-Small-Cell Lung

NCT03169777 2025-02-21

QUILT-3.050: NANT Colorectal Cancer (CRC) Vaccine: Combination Immunotherapy in Subjects With Recurrent or Metastatic CRC

Phase 1/2 Withdrawn

Gastrointestinal

Colorectal Neoplasms

NCT03197571 2025-02-21

QUILT-3.048: NANT Urothelial Cancer Vaccine: Combination Immunotherapy in Subjects With Urothelial Cancer Who Have Progressed on or After Chemotherapy and PD-1/PD-L1 Therapy

Phase 1/2 Withdrawn

Carcinoma, Transitional Cell

NCT06725121 2024-12-16

MacroTrans

Phase 1/2 Recruiting

Gastrointestinal

Carcinoma, Hepatocellular, Liver Neoplasms

NCT01217411 2024-11-19

RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer

Phase 1/2 Terminated

5 enrolled 6 charts

BreastCNSDermatologicThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Breast Neoplasms, Male, Small Cell Lung Carcinoma

NCT04220775 2024-11-07

Bintrafusp Alfa and Stereotactic Body Radiation Therapy for the Treatment of Recurrent or Second Primary Head and Neck Squamous Cell Cancer

Phase 1/2 Terminated

3 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck

NCT04098432 2024-09-23

CA209-9KH

Phase 1/2 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT03050554 2024-08-09

SBRT Combined With Avelumab (Anti-PD-L1) for Management of Early Stage Non-Small Cell Lung Cancer (NSCLC)

Phase 1/2 Terminated

2 enrolled 6 charts

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT02052648 2024-03-27

Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors

Phase 1/2 Completed

160 enrolled 21 charts

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT02782715 2024-03-20

Microwave Ablation With MRI-Guided SBRT Boost in Renal Cell Carcinoma

Phase 1/2 Terminated

3 enrolled 8 charts

Carcinoma, Renal Cell

NCT06243003 2024-02-07

WBRT With Hippocampal-avoidance Technique Followed by SRT for Extensive-stage SCLC With Baseline Brain Metastases

Phase 1/2 Recruiting

Brain Neoplasms

NCT03340974 2023-12-15

Pilot Dose Escalation Trial of Stereotactic Body Radiation Therapy (SBRT) in Combination With GC4419 in Pancreatic Cancer

Phase 1/2 Completed

42 enrolled 13 charts

Gastrointestinal

Pancreatic Neoplasms

NCT02407171 2023-10-31

Evaluating the Combination of MK-3475 and Sterotactic Body Radiotherapy in Patients With Metastatic Melanoma or NSCLC

Phase 1/2 Completed

61 enrolled 14 charts

DermatologicThoracic

Lung Neoplasms, Melanoma

NCT03399552 2023-10-23

Stereotactic Body Radiation Therapy and Avelumab Immunotherapy for Treatment of Malignant Mesothelioma

Phase 1/2 Completed

15 enrolled 8 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT05451173 2023-10-03

Combining ICI With SBRT or HypoFrx-RT for ES NSCLC

Phase 1/2 Unknown

Carcinoma, Non-Small-Cell Lung

NCT03522584 2023-06-12

Durvalumab, Tremelimumab and Hypofractionated Radiation Therapy in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Phase 1/2 Terminated

6 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck

NCT00547339 2022-12-07

Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer

Phase 1/2 Completed

94 enrolled 14 charts

Prostatic Neoplasms

NCT05641233 2022-12-07

FIBROPANC-1

Phase 1/2 Unknown

Gastrointestinal

Duodenal Neoplasms, Pancreatic Fistula, Pancreatic Neoplasms

NCT05265650 2022-07-19

Noelia

Phase 1/2 Unknown

Non-Small Cell Lung Cancer Metastatic

NCT00750269 2022-06-09

Stereotactic Body Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer

Phase 1/2 Completed

120 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04327986 2022-05-18

Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Advanced Pancreas Cancer

Phase 1/2 Terminated

3 enrolled 13 charts

Gastrointestinal

Pancreatic Neoplasms

NCT02563691 2022-03-08

CROP

Phase 1/2 Unknown

Prostatic Neoplasms

NCT05131711 2021-11-23

CSREIG

Phase 1/2 Unknown

Glioblastoma

NCT01120639 2021-08-06

Tx-Treatment

Phase 1/2 Completed

30 enrolled 19 charts

Brain Neoplasms, Glioblastoma, Neurologic Manifestations

NCT02721056 2021-05-10

NBTXR3 Crystalline Nanoparticles and Stereotactic Body Radiation Therapy in the Treatment of Liver Cancers

Phase 1/2 Terminated

Gastrointestinal

Liver Neoplasms

NCT02581384 2021-04-30

Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms Tumors

Phase 1/2 Terminated

5 enrolled 9 charts

GenitourinarySarcoma

Carcinoma, Renal Cell, Neoplasm Metastasis, Wilms Tumor, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT00152906 2020-08-14

Stereotactic Radiotherapy (SRT) Liver (COLD 1)

Phase 1/2 Completed

Gastrointestinal

Liver Neoplasms, Neoplasm Metastasis

NCT00777894 2019-05-15

Radiation Therapy in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

Phase 1/2 Completed

Gastrointestinal

Carcinoma, Hepatocellular, Liver Neoplasms