Clinical Trials

398 enrolled

Glioblastoma

NCT06448286 2026-02-19

PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma

60 enrolled

Phase 3 Active not recruiting

Glioblastoma

NCT05095376 2026-02-17

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

265 enrolled

CNSSarcoma

Glioblastoma, Gliosarcoma

NCT05331521 2026-02-03

ImproveCodel

406 enrolled

Oligodendroglioma

NCT06388733 2026-02-03

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

450 enrolled

Brain Neoplasms, Glioblastoma

NCT07375563 2026-01-29

NB-NK-2026

5 enrolled

Neuroblastoma, Ganglioneuroblastoma

NCT07215910 2025-10-14

Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

408 enrolled

CNSLymphoid

Astrocytoma, Lymphoma, Follicular

NCT06490536 2025-08-29

The Sagittarius Trial

700 enrolled

Gastrointestinal

Colonic Neoplasms

NCT05439278 2025-05-21

Conventional Versus Hypofractionated Radiotherapy With Temozolomide in Elderly Glioblastoma

178 enrolled

Glioblastoma

NCT05271240 2024-09-19

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

432 enrolled

Brain Neoplasms, Glioblastoma, Glioma

NCT06477939 2024-06-27

THREE-GLEES

554 enrolled

Hypoxia, Brain Neoplasms, Glioblastoma

NCT04532229 2023-07-27

Nimotuzumab in Combined With Chemoradiotherapy to Treat the Newly Diagnosed Diffuse Intrinsic Pontine Glioma in Children

48 enrolled

Diffuse Intrinsic Pontine Glioma

NCT05718466 2023-07-17

Stereotactic Radiology Versus Chemotherapy for Recurrent/Progressive Glioblastoma After Second-Line Chemotherapy

Phase 3 Completed

35 enrolled 13 charts

Glioblastoma, Recurrence

NCT02761070 2023-03-08

RE-GEND

146 enrolled

Glioblastoma, Recurrence, Disease Progression

NCT05600491 2022-10-31

A Phase III Study of Postoperative Early Temozolomide Treatment Plus STUPP Regimen for Newly Diagnosed GBM Multiforme

78 enrolled

Glioblastoma

NCT03243461 2022-06-06

HIT-HGG-2013

167 enrolled

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial

NCT04829097 2021-04-02

Neoadjuvant Temozolomide Combined With Simultaneous IMRT for Treatment of Glioblastoma

80 enrolled

Glioblastoma

NCT01649830 2020-05-28

Efficacy of Post-radiation Adjuvant Temozolomide Chemotherapy in Residue Low-grade Glioma

290 enrolled

Astrocytoma, Oligodendroglioma

NCT01014767 2019-08-20

Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors

Phase 3 Terminated

27 enrolled 1 chart

Brain Neoplasms, Choroid Plexus Neoplasms

NCT03633552 2018-08-16

Efficacy of Two Temozolomide Regimens in Adjuvant Treatment of Patients With Brain High Grade Glioma

62 enrolled

Astrocytoma, Glioblastoma

NCT01765088 2018-02-23

A Phase III Trial on Adjuvant Temozolomide With or Without Interferon-alpha in Newly Diagnosed High-grade Gliomas

300 enrolled

Astrocytoma, Glioblastoma, Glioma

NCT03435302 2018-02-19

HDI Versus Chemotherapy as Systemic Adjuvant Therapy for Resected Mucosal Melanoma

204 enrolled

Dermatologic

Melanoma

NCT01260103 2017-07-26

Phase 3 Study of ANP Therapy vs. TMZ for Optic Pathway Glioma

Phase 3 Withdrawn

Recurrence, Optic Nerve Glioma

NCT01149109 2017-06-14

CeTeG

Phase 3 Completed

141 enrolled

Glioblastoma

NCT01830101 2016-03-16

A Phase III Study of Re-Irradiation in Recurrent Glioblastoma

Phase 3 Withdrawn

Glioblastoma

NCT00897377 2014-08-05

Treatment Strategy for Low-grade Gliomas

Phase 3 Terminated

500 enrolled

Astrocytoma, Oligodendroglioma

NCT01502241 2011-12-30

Methusalem

Phase 3 Completed

412 enrolled