Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab
Phase 2 Completed
35 enrolled 13 charts
Avatar-Directed Chemotherapy in Treating Patients With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Phase 2 Completed
13 enrolled 14 charts
Berzosertib + Topotecan in Relapsed Platinum-Resistant Small-Cell Lung Cancer (DDRiver SCLC 250)
Phase 2 Completed
76 enrolled 42 charts
SGI-110
Phase 2 Completed
120 enrolled 22 charts
Efficacy and Safety of Aldoxorubicin Compared to Topotecan in Subjects With Metastatic Small Cell Lung Cancer
Phase 2 Completed
135 enrolled 11 charts
Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Phase 2 Completed
140 enrolled 8 charts
Comparison of Three Treatment Regimens in Treating Patients With Relapsed or Refractory Acute Myelogenous Leukemia
Phase 2 Completed
Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas
Phase 2 Completed
178 enrolled 16 charts
Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma
Phase 2 Completed
80 enrolled 11 charts
Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Phase 2 Completed
14 enrolled
Immunotherapy as Second-line in Patient With Small Cell Lung Cancer
Phase 2 Completed
73 enrolled
Topotecan in Treating Patients With Recurrent Brain Tumors
Phase 2 Completed
17 enrolled
Cyclophosphamide, Topotecan, and Bevacizumab (CTB) in Patients With Relapsed/Refractory Ewing's Sarcoma and Neuroblastoma
Phase 2 Completed
9 enrolled 9 charts
Veliparib, Topotecan Hydrochloride, and Filgrastim or Pegfilgrastim in Treating Patients With Persistent or Recurrent Cervical Cancer
Phase 2 Completed
27 enrolled 11 charts
Comparison of IV Topotecan/Docetaxel to Docetaxel Alone in Second-Line Stage IIIB/IV Non-Small Cell Lung Cancer
Phase 2 Completed
399 enrolled 12 charts
A Randomized Study to Compare the Efficacy and Safety of Belotecan and Topotecan as Monotherapy for Sensitive-Relapsed Small Cell Lung Cancer
Phase 2 Completed
164 enrolled
TMC (Topotecan, Cyclophosphamide and Melphalan) for Multiple Myeloma
Phase 2 Completed
60 enrolled
A Phase II Study of Paclitaxel and Topotecan With Filgrastim-SD/01 Support For Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma
Phase 2 Completed
25 enrolled
Topotecan in Treating Patients With Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
Phase 2 Completed
81 enrolled 10 charts
7-hydroxystaurosporine and Topotecan Hydrochloride in Treating Patients With Relapsed or Progressed Small Cell Lung Cancer
Phase 2 Completed
19 enrolled 9 charts
Weekly IV Topotecan and Cisplatin With Radiation in Cervical Carcinoma
Phase 2 Completed
12 enrolled
Topotecan and Bevacizumab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer That Did Not Respond to Previous Systemic Chemotherapy
Phase 2 Completed
46 enrolled 11 charts
S0802 - Topotecan With or Without Aflibercept in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Phase 2 Completed
189 enrolled 15 charts
Second-line Intravenous Treatment For Recurrent Platinum-Sensitive Ovarian, Fallopian, Or Peritoneal Cancer
Phase 2 Completed
75 enrolled
(SCLC)
Phase 2 Completed
60 enrolled
Cisplatin Induction With Paclitaxel Consolidation for Stage III-IV Epithelial Ovarian and Primary Peritoneal Cancer
Phase 2 Completed
40 enrolled
Combination Chemotherapy With or Without Filgrastim in Treating Patients With Previously Untreated Extensive-Stage Small Cell Lung Cancer
Phase 2 Completed
27 enrolled
Belotecan Versus Topotecan for Recurrent Ovarian Cancer: A Randomized, Open-label, Parallel-group Phase IIb Trial
Phase 2 Completed
141 enrolled
MIITOP
Phase 2 Completed
30 enrolled
Topotecan in Treating Patients With Myelodysplastic Syndrome
Phase 2 Completed
100 enrolled
Chemotherapy Plus Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer
Phase 2 Completed
75 enrolled
Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer
Phase 2 Completed
65 enrolled
Combination Chemotherapy in Treating Patients With Relapsed or Refractory Intermediate-Grade or High-Grade Non-Hodgkin's Lymphoma
Phase 2 Completed
Topotecan and Paclitaxel in Treating Patients With Recurrent or Refractory Small Cell Lung Cancer
Phase 2 Completed
84 enrolled
Topotecan, Paclitaxel, and Filgrastim in Treating Patients With Previously Untreated Extensive-Stage Small Cell Lung Cancer
Phase 2 Completed
38 enrolled
Carboplatin Plus Topotecan in Treating Patients With Relapsed Acute Myelogenous Leukemia
Phase 2 Completed
38 enrolled
Linsitinib or Topotecan Hydrochloride in Treating Patients With Relapsed Small Cell Lung Cancer
Phase 2 Completed
44 enrolled 10 charts
UCN-01 and Topotecan in Treating Patients With Recurrent, Persistent, or Progressive Advanced Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer
Phase 2 Completed
Comparing Three Different Combination Chemotherapy Regimens in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Phase 2 Completed
92 enrolled 10 charts
Ph II Study of Wkly Topotecan + Bevacizumab in Plat. Resistant/Recurrent Gyn Cancers
Phase 2 Completed
40 enrolled 10 charts
First-line Treatment Of Subjects With Extensive Disease Small Cell Lung Cancer With Weekly Hycamtin And Paraplatin
Phase 2 Completed
33 enrolled 10 charts
Vincristine Sulfate, Topotecan Hydrochloride, and Cyclophosphamide With or Without Bevacizumab in Treating Young Patients With Refractory or First Recurrent Extracranial Ewing Sarcoma
Phase 2 Completed
7 enrolled 6 charts
Topotecan, Cisplatin and Bevacizumab for Recurrent/Persistent Cervical Cancer
Phase 2 Completed
27 enrolled 14 charts
Topotecan Weekly Versus Topotecan Day 1-5 in Patient With Platin-resistant Ovarian Cancer
Phase 2 Completed
194 enrolled
Cyclophosphamide Plus Topotecan in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia
Phase 2 Completed
Lapatinib and Topotecan in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer That Did Not Respond to Cisplatin or Carboplatin
Phase 2 Completed
18 enrolled 10 charts
Topotecan and Paclitaxel in Treating Patients With Recurrent or Metastatic Cancer of the Cervix
Phase 2 Completed
25 enrolled
Use of Topotecan in Patients With Refractory Acute Leukemia
Phase 2 Completed
10 enrolled
Combination Chemotherapy in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Cancer
Phase 2 Completed
80 enrolled
ZD9331 With or Without Topotecan in Treating Patients With Refractory or Recurrent Epithelial Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Phase 2 Completed