Clinical Trials

1 enrolled 5 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT02649673 2023-12-05

LCL161 Plus Topotecan for Patients With Relapsed/Refractory Small Cell Lung Cancer and Select Gynecologic Malignancies

Phase EARLY_PHASE1 Terminated

34 enrolled

GynecologicThoracic

Lung Neoplasms, Ovarian Neoplasms, Small Cell Lung Carcinoma

NCT03927274 2023-05-25

Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma

Brain Neoplasms, Glioma

NCT02963090 2023-02-15

Pembrolizumab vs Topotecan in Patients With Small Cell Lung Cancer

9 enrolled 11 charts

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00014443 2023-01-09

Topotecan and Thalidomide in Treating Patients With Recurrent or Refractory Malignant Glioma

5 enrolled

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01803269 2020-06-26

Topotecan Hydrochloride or Cyclodextrin-Based Polymer-Camptothecin CRLX101 in Treating Patients With Recurrent Small Cell Lung Cancer

29 enrolled 14 charts

Small Cell Lung Carcinoma

NCT02684071 2020-01-10

Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors

Familial ependymoma, Ependymoma, Medulloblastoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor, Meningeal Carcinomatosis

NCT00003194 2019-04-05

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Solid Tumors

Phase EARLY_PHASE1 Terminated

24 enrolled

Other solid neoplasm

Unspecified Childhood Solid Tumor, Protocol Specific

NCT02500459 2019-03-01

Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection

9 enrolled

Brain Neoplasms, Glioma, Neoplasms

NCT00315211 2018-08-20

Weekly Topotecan With Docetaxel in Recurrent Small Cell Lung Cancer

7 enrolled

Mediastinal Neoplasms

NCT00720096 2018-01-02

Genomic Directed Salvage Chemotherapy With Either Liposomal Doxorubicin Or Topotecan

Phase NA Terminated

4 enrolled 8 charts

Ovarian Neoplasms

NCT00287859 2017-11-29

Topotecan in Treating Patients With Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer

5 enrolled

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00808899 2017-05-30

Neuroblastoma Protocol 2008: Therapy for Children With Advanced Stage High Risk Neuroblastoma

4 enrolled 5 charts

Neuroblastoma

NCT01003938 2016-06-30

Topotecan With Erlotinib for Topotecan Pretreated Ovarian Cancer

6 enrolled 7 charts

Ovarian Neoplasms

NCT00087048 2016-03-22

Topotecan in Treating Patients With Recurrent Extensive-Stage Small Cell Lung Cancer

1 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00526799 2016-03-03

Sorafenib + Topotecan for Platinum-Resistant Recurrent Ovarian Cancer

Phase 1/2 Terminated

30 enrolled 16 charts

Ovarian Neoplasms

NCT00812266 2016-01-26

Topotecan and Cisplatin Versus Etoposide and Carboplatin in 1st Line Treatment of Patients With Small Cell Lung Cancer and Extensive Disease (SCLC-ED)

Phase 3 Terminated

281 enrolled

Small Cell Lung Carcinoma

NCT00002948 2014-07-02

High-Dose Topotecan and Peripheral Stem Cell Transplantation in Treating Patients With Refractory Cancer

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00697476 2013-05-29

Study of Oral Vorinostat in Combination With Topotecan in Patients With Chemosensitive Recurrent SCLC

Phase 1/2 Terminated

2 enrolled

Small Cell Lung Carcinoma

NCT00006032 2012-12-11

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast Cancer

Breast

Breast Neoplasms

NCT01177501 2012-11-19

ITOV04

Ovarian Neoplasms, Recurrence

NCT00005612 2012-09-26

ETC

Phase 1/2 Terminated

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00888810 2009-04-28

TOPO-LAPA

39 enrolled

Neoplasms, Recurrence

NCT00322920 2008-02-15

Efficacy Study of Weekly Topotecan With Cisplatin in Advanced Stage or Recurrent Cervical Cancer

30 enrolled

Uterine Cervical Neoplasms

NCT00194935 2006-09-13

Weekly Topotecan Therapy in Patients With Ovarian Cancer

32 enrolled