Clinical Trials Browser

Interventional × Tretinoin × Clear all

NCT05345002 2026-02-20

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

Phase 2 Recruiting

Astrocytoma, Glioma, Oligodendroglioma

NCT04919369 2026-02-13

All-Trans Retinoic Acid (ATRA) and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer

Phase 1 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06358677 2026-02-13

FACE

Phase 2 Recruiting

Neoplasm Metastasis

NCT07348107 2026-01-16

ATARI-PDAC

Phase 1 Not yet recruiting

Neoplasm Metastasis

NCT04241276 2026-01-07

STARPAC2

Phase 2 Active not recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT07296445 2025-12-29

LATITUDE

Phase 3 Not yet recruiting

Other hematologic neoplasm

Leukemia, Leukemia, Promyelocytic, Acute

NCT04113863 2025-12-18

ATRA

Phase 2 Terminated

Breast Neoplasm Female

NCT01409161 2025-12-17

Tretinoin and Arsenic Trioxide With or Without Gemtuzumab Ozogamicin in Treating Patients With Previously Untreated Acute Promyelocytic Leukemia

Phase 2 Recruiting

Other hematologic neoplasm

Leukemia, Promyelocytic, Acute

NCT06439888 2025-12-01

LySATRA

Phase 1/2 Recruiting

Other solid neoplasm

Oligometastatic Disease

NCT06731140 2025-11-17

Resilire

Phase 2 Recruiting

HER2 Negative Breast Cancer

NCT06528769 2025-09-30

Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma

Phase 2 Recruiting

Leiomyosarcoma, Sarcoma

NCT07187505 2025-09-23

Venetoclax Combined With ATRA and ATO in Hyperleukocytic Acute Promyelocytic Leukemia

Phase NA Active not recruiting

Other hematologic neoplasm

Leukemia, Promyelocytic, Acute

NCT04305041 2025-08-29

KEYMAKER-U02

Phase 1/2 Completed

Parkinson Disease 4, Autosomal Dominant Lewy Body, Melanoma

NCT05999812 2025-05-25

Clinical Trial of All-trans-retinoic Acid, Bevacizumab and Atezolizumab in Colorectal Cancer

Phase 2 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06536413 2025-04-08

ATRA

Phase 1/2 Recruiting

Multiple Myeloma

NCT02688140 2025-02-26

TUD-APOLLO-064

Phase 3 Completed

Other hematologic neoplasm

Leukemia, Promyelocytic, Acute

NCT04700176 2025-02-25

A Study of Daratumumab With Pomalidomide, Dexamethasone, and All-Transretinoic Acid in Patients With Multiple Myeloma

Phase 2 Terminated

1 enrolled 14 charts

Multiple Myeloma

NCT06728631 2025-02-24

Candonilimab and ATRA Acid for Prevention of Oral Cancer Recurrence in Patients With OPL

Phase 2 Active not recruiting

Mouth Neoplasms

NCT06158412 2025-02-19

All-trans Retinoic Acid in Combination With a KPD Regimen for the Treatment of Refractory/Relapsed Multiple Myeloma

Phase 2 Recruiting

Multiple Myeloma

NCT04282668 2024-12-09

A Study of TAS1440 With ATRA in Subjects With r/r AML

Phase 1 Terminated

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT06646666 2024-11-01

ARTA-based Chemo-free Bridging/Maintenance Therapy in CAR-T Treatment for High-Risk R/R B-NHL Ineligible for HDCT and ASCT

Phase 2 Not yet recruiting

Lymphoma, B-Cell

NCT03200847 2024-10-01

Pembrolizumab and All-Trans Retinoic Acid Combination Treatment of Advanced Melanoma

Phase 1/2 Completed

26 enrolled 13 charts

Melanoma

NCT05482451 2024-08-21

Nivolumab and All-trans Retinoic Acid for Pancreatic Cancer

Phase EARLY_PHASE1 Active not recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT05832320 2024-05-10

Optimum Induction Therapy of Low-risk APL

Phase NA Recruiting

Other hematologic neoplasm

Leukemia, Promyelocytic, Acute

NCT02942758 2024-05-08

AML-ViVA

Phase 2 Terminated

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT03572387 2024-04-30

A Pilot Study of 5-AZA and ATRA for Prostate Cancer With PSA-only Recurrence After Local Treatment

Phase 2 Completed

14 enrolled 9 charts

Prostatic Neoplasms

NCT04793919 2024-04-15

Treatment Study for Children and Adolescents With Acute Promyelocytic Leukemia

Phase 2 Recruiting

Other hematologic neoplasm

Leukemia, Promyelocytic, Acute

NCT03878524 2024-03-04

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Phase 1 Terminated

BreastClassical hematologyGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmPlasma cell

Anemia, Blast Crisis, Breast Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Thrombocytosis, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT02403778 2023-09-21

Ipilimumab and All-Trans Retinoic Acid Combination Treatment of Advanced Melanoma

Phase 2 Completed

10 enrolled 12 charts

Melanoma

NCT02842827 2023-07-11

IMG-7289-CTP-101

Phase 1/2 Completed

45 enrolled 41 charts

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT00003601 2023-06-18

Tretinoin With or Without Fenretinide in Treating Patients With Dysplastic Nevus Syndrome

Phase 2 Completed

Melanoma

NCT02751255 2023-04-28

DARA/ATRA

Phase 1/2 Completed

Multiple Myeloma

NCT03999684 2023-01-23

A Trial of All-trans Retinoic Acid (ATRA) in Advanced Adenoid Cystic Carcinoma

Phase 2 Completed

18 enrolled 8 charts

Carcinoma, Adenoid Cystic

NCT00551460 2023-01-10

S0535, Gemtuzumab and Combination Chemotherapy in Treating Patients With Previously Untreated Acute Promyelocytic Leukemia

Phase 2 Completed

78 enrolled 8 charts

Other hematologic neoplasm

Leukemia, Leukemia, Promyelocytic, Acute

NCT02641782 2022-11-04

NB2013-HR

Phase 2 Terminated

Neuroblastoma

NCT05497310 2022-10-26

Effectiveness and Safety of Therapy Based on Attenuated ATO Plus Low-Dose ATRA in Patients With APL

Phase 1/2 Unknown

Other hematologic neoplasm

Leukemia, Promyelocytic, Acute

NCT00866918 2022-10-25

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Promyelocytic Leukemia

Phase 3 Completed

106 enrolled 14 charts

MyeloidOther hematologic neoplasm

Childhood Acute Promyelocytic Leukemia With PML-RARA

NCT00482833 2022-10-12

APL0406

Phase 3 Completed

Other hematologic neoplasm

Leukemia, Leukemia, Promyelocytic, Acute

NCT05297123 2022-03-28

Treatment of Acute Myeloid Leukemia With Arsenic and All-trans Retinoid Acid

Phase 1 Unknown

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT05175508 2022-01-03

Aza With or Without ATRA in Newly Diagnosed Unfit AML or Intermediate,High or Very High Risk MDS

Phase 2/3 Unknown

MyeloidOther hematologic neoplasm

Frailty, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT01404949 2021-11-30

Combined Tretinoin and Arsenic Trioxide for Patients With Newly Diagnosed Acute Promyelocytic Leukemia Followed by Risk-Adapted Postremission Therapy

Phase 2 Completed

17 enrolled 8 charts

Other hematologic neoplasm

Leukemia, Promyelocytic, Acute

NCT02899169 2021-09-08

APL16

Phase 3 Unknown

Other hematologic neoplasm

Leukemia, Promyelocytic, Acute

NCT05016349 2021-08-23

Investigating the Potential Role of a Novel Quadrate Combination Therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic Acid and Cannabidiol ( Selective Cyp 26 Inhibitor) for Treating Early Breast Cancer.

Phase 3 Unknown

Breast Cancer Female

NCT01064557 2020-10-14

"AIDA" Protocol (LAP 0493)

Phase NA Unknown

Other hematologic neoplasm

Leukemia, Leukemia, Promyelocytic, Acute

NCT01064570 2020-10-14

AIDA 2000 Guidelines

Phase 2 Unknown

Other hematologic neoplasm

Leukemia, Promyelocytic, Acute

NCT02273102 2020-07-21

TCP-ATRA

Phase 1 Completed

MyeloidOther hematologic neoplasm

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT03307148 2020-01-22

STAR_PAC

Phase 1 Completed

Neoplasm Metastasis

NCT00617409 2019-11-08

To Immunize Patients With Extensive Stage SCLC Combined With Chemo With or Without All Trans Retinoic Acid

Phase 2 Completed

69 enrolled 10 charts

Small Cell Lung Carcinoma

NCT01987297 2019-08-19

Combined Retinoic Acid,Arsenic Trioxide and Chemo for Newly-diagnosed APL

Phase 4 Unknown

Other hematologic neoplasm

Leukemia, Promyelocytic, Acute

NCT02717884 2018-10-18

TRANSATRA

Phase 1/2 Unknown

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Recurrence, Leukemia, Myeloid, Acute