NCT06008119 2025-09-18Efficacy and Safety of Tunlametinib Plus Vemurafenib in Patients With BRAF V600E-mutant Metastatic Colorectal CancerShanghai Kechow Pharma, Inc.Phase 3 Recruiting165 enrolled
NCT02908672 2025-07-20A Study of Atezolizumab Plus Cobimetinib and Vemurafenib Versus Placebo Plus Cobimetinib and Vemurafenib in Previously Untreated BRAFv600 Mutation-Positive Patients With Metastatic or Unresectable Locally Advanced MelanomaHoffmann-La RochePhase 3 Completed514 enrolled 25 charts 2 FDA
NCT02427893 2016-11-15Trial of Vemurafenib and Cobimetinib in Patients With Advanced BRAFV600 Mutant MelanomaSidney Kimmel Comprehensive Cancer Center at Johns HopkinsPhase 3 Withdrawn
NCT01006980 2016-09-28A Study of Vemurafenib (RO5185426) in Comparison With Dacarbazine in Previously Untreated Patients With Metastatic Melanoma (BRIM 3)Hoffmann-La RochePhase 3 Completed675 enrolled 14 charts