Clinical Trials Browser

Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, T-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Intraocular Lymphoma

NCT00667082 2017-11-22

NPI-0052 and Vorinostat in Patients With Non-small Cell Lung Cancer, Pancreatic Cancer, Melanoma or Lymphoma

Phase 1 Completed

22 enrolled

DermatologicGastrointestinalLymphoidPlasma cellThoracic

Carcinoma, Non-Small-Cell Lung, Lymphoma, Melanoma, Multiple Myeloma, Pancreatic Neoplasms

NCT00946673 2017-10-06

Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer

Phase 1 Completed

17 enrolled

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00788112 2017-08-07

Vorinostat in Treating Women With Ductal Carcinoma in Situ of the Breast

Phase 1 Completed

17 enrolled

Breast

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT01130506 2017-08-02

Decitabine, Vorinostat, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Phase 1 Completed

17 enrolled

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT01339871 2017-06-16

Study of Pazopanib and Vorinostat in Patients With Advanced Malignancies

Phase 1 Completed

152 enrolled

Advanced Cancer

NCT00731952 2017-05-04

Phase I Study of Induction Therapy With VELCADE and Vorinostat in Patients With Surgically Resectable Non-Small Cell Lung Cancer

Phase 1 Completed

21 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00750178 2017-04-07

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK0683 in Patients With Advanced Cancer (0683-008)

Phase 1 Completed

30 enrolled

Tumor-Agnostic

Neoplasms

NCT00719875 2017-03-03

HDAC Inhibitor Vorinostat (SAHA) With Capecitabine (Xeloda) Using a New Weekly Dose Regimen for Advanced Breast Cancer

Phase 1 Completed

24 enrolled

Breast

Advanced Breast Cancer

NCT00423449 2016-02-04

Clinical Trial of MK0683 in Combination With FDA Approved Cancer Drugs in Patients With Advanced NSCLC (MK0683-058)

Phase 1 Completed

61 enrolled 9 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01276717 2015-12-03

Study of Carfilzomib and Vorinostat for Relapsed or Refractory Lymphoma

Phase 1 Completed

20 enrolled

Lymphoid

Lymphoma

NCT01208454 2015-11-24

Vorinostat and Isotretinoin in Treating Patients With High-Risk Refractory or Recurrent Neuroblastoma

Phase 1 Completed

29 enrolled

CNS

Neuroblastoma

NCT01421173 2015-11-18

Vorinostat With Gemcitabine, Busulfan, and Melphalan With Stem Cell Transplant (SCT) in Relapsed or Refractory Lymphoid Malignancies

Phase 1 Completed

78 enrolled

Lymphoid

Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Recurrence

NCT00127140 2015-09-28

A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Malignant Lymphoma (0683-030)

Phase 1 Completed

10 enrolled

Lymphoid

Lymphoma

NCT00479232 2015-09-21

Phase I Trial of Vorinostat (MK-0683, SAHA) in Combination With Decitabine in Patients With AML or MDS (MK-0683-055 EXT1)

Phase 1 Completed

71 enrolled 9 charts

MyeloidOther hematologic neoplasm

Leukemia, Myelodysplastic Syndromes

NCT00632931 2015-07-30

A Crossover Study to Assess the Effects of Vorinostat (MK0683, SAHA) in Patients With Advanced Cancer (0683-070)(COMPLETED)

Phase 1 Completed

25 enrolled 21 charts

Advanced Cancer Relapsed

NCT00121277 2015-07-23

Vorinostat and Capecitabine in Treating Patients With Metastatic or Unresectable Solid Tumors

Phase 1 Completed

28 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00561418 2015-07-16

Vorinostat After Stem Cell Transplant in Treating Patients With High-Risk Lymphoma

Phase 1 Completed

23 enrolled 7 charts

LymphoidOther hematologic neoplasm

Hodgkin Disease, Immunoblastic Lymphadenopathy, Lymphoma, Lymphoma, Follicular, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Large-Cell, Anaplastic, Lymphoma, Mantle-Cell, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell

NCT00983268 2015-06-15

Capecitabine, Vorinostat, and Radiation Therapy in Treating Patients With Nonmetastatic Pancreatic Cancer

Phase 1 Completed

21 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT00111813 2015-05-21

Phase 1 Study of Vorinostat and Bortezomib in Multiple Myeloma (MK-0683-015 EXT 1 (AM1))

Phase 1 Completed

34 enrolled 10 charts

Plasma cell

Multiple Myeloma

NCT00771472 2015-04-21

Vorinostat (MK-0683) Phase I Study in Cutaneous T-Cell Lymphoma (CTCL) Patients (MK-0683-089 EXT1)

Phase 1 Completed

10 enrolled 11 charts

Lymphoid

Lymphoma

NCT00875745 2014-09-18

Combination of Sorafenib and Vorinostat in Poor-risk Acute Myelogenous Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)

Phase 1 Completed

15 enrolled

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Promyelocytic, Acute

NCT00275080 2014-08-27

Vorinostat and Decitabine in Treating Patients With Advanced Solid Tumors or Relapsed or Refractory Non-Hodgkin's Lymphoma, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Chronic Myelogenous Leukemia

Phase 1 Completed

80 enrolled

LymphoidOther hematologic neoplasm

Congenital Abnormalities, Blast Crisis, Burkitt Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00217412 2014-06-17

Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia

Phase 1 Completed

60 enrolled

CNSLymphoidOther hematologic neoplasmSarcoma

Burkitt Lymphoma, Medulloblastoma, Neuroblastoma, Recurrence, Lymphoma, Large B-Cell, Diffuse, Rhabdoid Tumor, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating