Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell Transplant
Phase 1 Completed
50 enrolled
Epigenetic Reprogramming in Relapse/Refractory AML
Phase 1 Completed
37 enrolled 11 charts
Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed Glioblastoma
Phase 1 Completed
21 enrolled 12 charts
HDAC Inhibitor Vorinostat in Resistant BRAF V600 Mutated Advanced Melanoma
Phase 1/2 Completed
33 enrolled
Study of the Combination of Vorinostat and Radiation Therapy for the Treatment of Patients With Brain Metastases
Phase 1 Completed
17 enrolled 8 charts
MIBG With Dinutuximab +/- Vorinostat
Phase 1 Completed
45 enrolled 16 charts
Vorinostat and Temsirolimus With or Without Radiation Therapy in Treating Younger Patients With Newly Diagnosed or Progressive Diffuse Intrinsic Pontine Glioma
Phase 1 Completed
18 enrolled
PEVOsq
Phase 2 Completed
112 enrolled
Pembrolizumab and Vorinostat in Treating Patients With Recurrent Squamous Cell Head and Neck Cancer or Salivary Gland Cancer That Is Metastatic and/or Cannot Be Removed by Surgery
Phase 1/2 Completed
50 enrolled 13 charts
Vorinostat Plus Hydroxychloroquine Versus Regorafenib in Colorectal Cancer
Phase 2 Completed
42 enrolled 8 charts
PRAVO
Phase 1 Completed
15 enrolled
N2007-03: Vorinostat and 131-I MIBG in Treating Patients With Resistant or Relapsed Neuroblastoma
Phase 1 Completed
27 enrolled
Hydroxychloroquine + Vorinostat in Advanced Solid Tumors
Phase 1 Completed
72 enrolled
GemTax
Phase 1/2 Completed
37 enrolled 17 charts
Neoadjuvant Chemotherapy Followed by Radiation Therapy and Gemcitabine/Sorafenib/Vorinostat in Pancreatic Cancer
Phase 1 Completed
23 enrolled
MLN9708 and Vorinostat in Patients With Advanced p53 Mutant Malignancies
Phase 1 Completed
68 enrolled
N2011-01
Phase 2 Completed
114 enrolled 13 charts
RZD
Phase 1/2 Completed
25 enrolled 5 charts
Fludarabine Phosphate, Clofarabine, and Busulfan With Vorinostat in Treating Patients With Acute Leukemia in Remission or Relapse Undergoing Donor Stem Cell Transplant
Phase 1 Completed
70 enrolled
Clinical Study of Vorinostat in Combination With Etoposide in Pediatric Patients < 21 Years at Diagnosis With Refractory Solid Tumors
Phase 1/2 Completed
27 enrolled 11 charts
A Study of the Combination Vorinostat With Lenalidomide, Bortezomib and Dexamethasone for Patients With Newly Diagnosed Multiple Myeloma
Phase 1 Completed
30 enrolled
Sirolimus or Vorinostat and Hydroxychloroquine in Advanced Cancer
Phase 1 Completed
143 enrolled
Ridaforolimus and Vorinostat in Treating Patients With Advanced Solid Tumors or Lymphoma
Phase 1 Completed
16 enrolled 7 charts
SAHA
Phase 1 Completed
40 enrolled 13 charts
Vorinostat in Combination With Palliative Radiotherapy for Patients With Non-Small Cell Lung Cancer
Phase 1 Completed
17 enrolled 5 charts
Trial for Locally Advanced Breast Cancer Using Vorinostat Plus Chemotherapy
Phase 1/2 Completed
55 enrolled 10 charts
Vorinostat and Lenalidomide After Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma
Phase 1 Completed
19 enrolled
Vorinostat, Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Phase 1/2 Completed
40 enrolled 14 charts
Vorinostat in Combination With Azacitidine in Patients With Newly-Diagnosed Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Phase 2 Completed
110 enrolled 9 charts
Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma
Phase 1/2 Completed
61 enrolled 10 charts
Vorinostat in Treating Patients With Stage IV Breast Cancer Receiving Hormone Therapy
Phase NA Completed
15 enrolled 10 charts
Vorinostat and Bortezomib as Third-line Treatment in Advanced Non-small Cell Lung Cancer
Phase 2 Completed
18 enrolled 16 charts
NSCLC
Phase 1 Completed
18 enrolled
Ixabepilone and Vorinostat in Treating Patients With Metastatic Breast Cancer
Phase 1 Completed
56 enrolled
Vorinostat in Treating Patients With Stage IV Breast Cancer Receiving Aromatase Inhibitor Therapy
Phase NA Completed
8 enrolled 10 charts
Ph I Vorinostat in the Treatment of Advanced Staged Oropharyngeal Squamous Cell Carcinoma
Phase 1 Completed
27 enrolled
SAHA-I
Phase 2 Completed
40 enrolled
A Clinical Trial to Validate Molecular Targets of Vorinostat in Patients With Aerodigestive Tract Cancer
Phase NA Completed
10 enrolled 7 charts
Phase I/II Study of Combination of Sorafenib, Vorinostat, and Bortezomib for the Treatment of Acute Myeloid Leukemia With Complex- or Poor-risk (Monosomy 5/7) Cytogenetics or FLT3-ITD Positive Genotype
Phase 1/2 Completed
37 enrolled 12 charts
Vorinostat Plus Tacrolimus & Methotrexate to Prevent Graft vs Host Disease Following Unrelated Stem Cell Transplant
Phase 2 Completed
26 enrolled 9 charts
Vorinostat and Rituximab in Treating Patients With Indolent Non-Hodgkin Lymphoma
Phase 2 Completed
30 enrolled 8 charts
Trial of Vorinostat in Combination With Cyclophosphamide, Etoposide, Prednisone and Rituximab for Elderly Patients With Relapsed Diffuse Large B-Cell Lymphoma (DLBCL)
Phase 1/2 Completed
30 enrolled 9 charts
Vorinostat, Cladribine, and Rituximab in Treating Patients With Mantle Cell Lymphoma, Relapsed Chronic Lymphocytic Leukemia, or Relapsed B Cell Non-Hodgkin's Lymphoma
Phase 2 Completed
57 enrolled 14 charts
Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer
Phase 1 Completed
17 enrolled
Vorinostat in Treating Women With Ductal Carcinoma in Situ of the Breast
Phase 1 Completed
17 enrolled
Study of Pazopanib and Vorinostat in Patients With Advanced Malignancies
Phase 1 Completed
152 enrolled
Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantle Cell Lymphoma
Phase 1/2 Completed
29 enrolled 10 charts
Phase I Study of Induction Therapy With VELCADE and Vorinostat in Patients With Surgically Resectable Non-Small Cell Lung Cancer
Phase 1 Completed
21 enrolled
Study of 5-azacitidine in Combination With Vorinostat in Patients With Relapsed or Refractory Diffuse Large b Cell Lymphoma (DLBCL)
Phase 1/2 Completed
17 enrolled 3 charts
Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients
Phase 2 Completed
48 enrolled 10 charts