Clinical Trials

33 enrolled 22 charts

Carcinoma, Non-Small-Cell Lung

NCT01413750 2024-11-12

Carboplatin and Paclitaxel With or Without Vorinostat in Treating Patients With Advanced Non-Small Cell Lung Cancer

23 enrolled 10 charts

Stage IIIA Lung Non-Small Cell Cancer AJCC v7

NCT03878524 2024-03-04

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

BreastClassical hematologyGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmPlasma cell

2 enrolled

Anemia, Blast Crisis, Breast Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Thrombocytosis, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT04190056 2023-08-31

Pembrolizumab and Tamoxifen With or Without Vorinostat for the Treatment of Estrogen Receptor Positive Breast Cancer

1 enrolled 4 charts

Anatomic Stage IV Breast Cancer AJCC v8

NCT03713320 2022-04-08

SOLAR

37 enrolled 23 charts

Immune System Diseases, Immunoproliferative Disorders, Lymphatic Diseases, Lymphoma, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Mycosis Fungoides, Neoplasms, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous

NCT00785798 2022-04-04

Vorinostat and Pegylated Liposomal Doxorubicin in Relapsed or Refractory Lymphomas

17 enrolled 4 charts

Lymphoid

Lymphoma

NCT01110876 2021-08-25

Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)

21 enrolled 8 charts

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT03050450 2021-04-05

Study of Lenalidomide With Vorinostat in Pediatric Patients With High Grade or Progressive CNS Tumors

8 enrolled 10 charts

CNS

Central Nervous System Neoplasms

NCT00324740 2021-02-23

Vorinostat and Isotretinoin in Treating Patients With Advanced Kidney Cancer

14 enrolled 8 charts

Genitourinary

Carcinoma, Renal Cell

NCT01483690 2020-10-27

A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALL

23 enrolled 13 charts

Leukemia, Recurrence, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT01249443 2020-07-29

Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection

BreastGastrointestinalGynecologicHead & NeckThoracic

17 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Anus Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, HIV Infections

NCT02395627 2020-07-07

Reversing Therapy Resistance With Epigenetic-Immune Modification

38 enrolled 18 charts

Breast Neoplasms

NCT02589145 2019-12-13

Lenalidomide Combined With Vorinostat/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Diffuse Large B-Cell Lymphoma of the ABC Subtype

8 enrolled 11 charts

Lymphoid

Lymphoma, Lymphoma, Large B-Cell, Diffuse

NCT00109109 2019-11-14

A Clinical Trial of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Advanced Multiple Myeloma (0683-004)

60 enrolled

Plasma cell

Multiple Myeloma

NCT01118975 2019-11-13

GCC 0845:Vorinostat and Lapatinib in Advanced Solid Tumors and Advanced Breast Cancer to Evaluate Response and Biomarkers

12 enrolled 6 charts

Breast Neoplasms, Neoplasm Metastasis

NCT02412475 2019-01-24

Epigenetic Reprogramming in Relapse AML

Other hematologic neoplasm

3 enrolled

Leukemia, Myeloid, Acute

NCT00702962 2018-10-22

Carboplatin and Etoposide in Combination With Vorinostat for Patients With Extensive Stage Small Cell Lung Cancer

8 enrolled 8 charts

Lung Neoplasms, Small Cell Lung Carcinoma

NCT00958074 2018-10-18

Vorinostat in Patients With Primary Cutaneous T-Cell Lymphoma

11 enrolled 11 charts

Lymphoma, T-Cell, Cutaneous

NCT00910000 2018-09-10

Vorinostat, Carboplatin and Gemcitabine in Women With Recurrent, Platinum-Sensitive Ovarian Cancer

15 enrolled 12 charts

Gynecologic

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT02419755 2018-03-07

Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic Malignancies

12 enrolled 10 charts

Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00744354 2018-01-18

Vorinostat, Bortezomib, and Doxorubicin Hydrochloride Liposome in Treating Patients With Relapsed or Refractory Multiple Myeloma

32 enrolled

Plasma cell

Multiple Myeloma, Neoplasms, Plasma Cell

NCT00818649 2017-12-28

Bortezomib and Vorinostat in Treating Patients With High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia

Classical hematologyMyeloidOther hematologic neoplasm

16 enrolled 7 charts

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT00882206 2017-12-28

Pre-reinductive Decitabine and Vorinostat in Relapsed Lymphoblastic Lymphoma or Acute Lymphoblastic Leukemia

15 enrolled 8 charts

Leukemia, Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01312818 2017-12-28

Bortezomib, Vorinostat and Dexamethasone for Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL)

2 enrolled 6 charts

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01187446 2017-11-20

Low-dose (12 Gy) TSEBT+Vorinostat Versus Low-dose TSEBT Monotherapy in Mycosis Fungoides

28 enrolled 13 charts

Lymphoma, T-Cell, Cutaneous

NCT00857324 2017-09-06

Study of Vorinostat Plus Melphalan and Prednisone (Zmp) in Advanced, Refractory Multiple Myeloma Patients

18 enrolled

Plasma cell

Multiple Myeloma

NCT00662311 2017-06-14

Vorinostat, Paclitaxel, and Radiation Therapy in Treating Patients Unable to Tolerate Cisplatin With Stage III Non-Small Lung Cancer That Cannot Be Removed By Surgery

5 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung

NCT00673153 2017-06-01

Vorinostat and Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia

Other hematologic neoplasm

31 enrolled 11 charts

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT00948688 2017-05-10

Vorinostat With XRT and 5-FU for Locally Advanced Adenocarcinoma of the Pancreas

10 enrolled 12 charts

Gastrointestinal

Pancreatic Neoplasms

NCT01267240 2017-04-14

Capecitabine and Vorinostat in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer

25 enrolled 9 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT00126451 2017-04-10

A Clinical Trial of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Relapsed or Refractory Breast, Colorectal and Non-Small Cell Lung Cancer (0683-011)(TERMINATED)

BreastGastrointestinalThoracic

16 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT00976183 2017-04-10

Paclitaxel, Carboplatin and Vorinostat for the Treatment of Advanced Stage Ovarian Carcinoma

18 enrolled 7 charts

Gynecologic

Ovarian Neoplasms

NCT00565227 2016-12-02

Phase I Study of Vorinostat in Combination With Docetaxel in Patients With Advanced and Relapsed Solid Malignancies.

12 enrolled

GenitourinaryThoracic

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Prostatic Neoplasms

NCT00702572 2016-09-22

Carboplatin, Paclitaxel, Bevacizumab and Vorinostat for Patients With Advanced Non-Small Cell Lung Cancer

25 enrolled

Carcinoma, Non-Small-Cell Lung

NCT01500538 2016-02-15

VEIL

Classical hematologyLymphoid

1 enrolled

Lymphoma, Lymphoma, Follicular, Thrombocytopenia, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

NCT00127101 2015-04-21

An Investigational Study of a Histone Deacetylase (HDAC) Inhibitor Plus Targretin in Cutaneous T-Cell Lymphoma Patients (0683-016)(TERMINATED)

23 enrolled 13 charts

Lymphoid

Lymphoma

NCT00424775 2015-04-20

A Study of Carboplatin + Paclitaxel and MK0683 in Patients With Chemotherapy-naive Non-Small Cell Lung Cancer (NSCLC)(0683-066)

3 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT00132002 2015-03-19

Suberoylanilide Hydroxamic Acid in Treating Patients With Progressive Stage IV Breast Cancer

14 enrolled 6 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT00251589 2015-03-06

A Phase I/II Clinical Trial of Vorinostat in Combination With Erlotinib for Patients With Relapsed/Refractory Non-Small-Cell Lung Cancer (0683-025)

23 enrolled 15 charts

Carcinoma, Non-Small-Cell Lung

NCT00363883 2015-02-13

Vorinostat in Treating Patients With Locally Recurrent or Metastatic Cancer of the Urothelium

14 enrolled 6 charts

Genitourinary

Localized Transitional Cell Cancer of the Renal Pelvis and Ureter

NCT01600742 2014-01-09

Vorinostat and Concurrent Whole Brain Radiotherapy for Brain Metastasis

4 enrolled

CNS

Brain Neoplasms

NCT00697476 2013-05-29

Study of Oral Vorinostat in Combination With Topotecan in Patients With Chemosensitive Recurrent SCLC

2 enrolled

Small Cell Lung Carcinoma

NCT01194427 2013-05-17

A Study of Vorinostat and Tamoxifen in Newly Diagnosed Breast Cancer

2 enrolled 3 charts

Breast Neoplasms

NCT00810576 2012-08-07

Combination of Vorinostat and Bortezomib in Relapsed or Refractory T-Cell Non-Hodgkin's Lymphoma

1 enrolled 3 charts

Subcutaneous panniculitis-like T-cell lymphoma, Immunoblastic Lymphadenopathy, Lymphoma, Lymphoma, T-Cell, Lymphoma, T-Cell, Peripheral, Lymphoma, Large-Cell, Anaplastic, Enteropathy-Associated T-Cell Lymphoma

NCT00831493 2012-02-28

Vorinostat Plus Radiation Therapy in Pancreatic Cancer

3 enrolled 3 charts

Gastrointestinal

Pancreatic Neoplasms

NCT01116154 2010-12-09

Vorinostat and Lenalidomide in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma

DermatologicLymphoidOther hematologic neoplasm

30 enrolled

Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, T-Cell, Peripheral, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Intraocular Lymphoma

NCT00801151 2010-05-20

Vorinostat in Combination With Vinorelbine in Patients With Advanced Cancer