Clinical Trials Browser

Phase 3 × Interventional × Zoledronic Acid × Clear all

NCT03295981 2025-10-15

Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

Phase 3 Recruiting

Giant Cell Tumor of Bone

NCT00470223 2025-06-08

OS2006

Phase 3 Active not recruiting

Sarcoma, Osteosarcoma

NCT00295646 2024-03-15

Tamoxifen Versus Anastrozole, Alone or in Combination With Zoledronic Acid

Phase 3 Completed

1,803 enrolled 20 charts

Breast Neoplasms

NCT06221072 2024-01-24

A Study to Assess the Prevention of Bone-related Events in Patients With Bone Metastases From Malignant Solid Tumors Treated With JMT103 Compared to Zoledronic Acid

Phase 3 Not yet recruiting

Imaging Examination Shows at Least One Site With Bone Metastases From Soild Tumors

NCT00556374 2023-07-27

Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy

Phase 3 Completed

3,420 enrolled 19 charts

Breast Neoplasms

NCT05866172 2023-05-19

HAIC Combined Withzoledronic Acid for the Prevention of Bone Metastases in Advanced HCC

Phase 3 Unknown

Gastrointestinal

Carcinoma, Hepatocellular

NCT00412022 2023-03-24

HOBOE

Phase 3 Unknown

Breast Neoplasms

NCT00321464 2022-11-08

A Study Comparing Denosumab vs. Zoledronic Acid for the Treatment of Bone Metastases in Breast Cancer Subjects.

Phase 3 Completed

2,049 enrolled 16 charts

Breast Neoplasms, Fractures, Bone

NCT01345019 2022-11-08

Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma

Phase 3 Completed

1,718 enrolled 22 charts

Other hematologic neoplasmPlasma cellSarcoma

Blood Protein Disorders, Bone Diseases, Bone Marrow Diseases, Bone Neoplasms, Hematologic Diseases, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Neoplastic Processes, Paraproteinemias, Spinal Cord Compression, Hematologic Neoplasms, Fractures, Bone, Neoplasms, Plasma Cell

NCT00330759 2022-11-07

Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma.

Phase 3 Completed

1,779 enrolled 14 charts

LymphoidPlasma cell

Lymphoma, Multiple Myeloma, Spinal Cord Compression

NCT05164952 2021-12-21

Delayed Versus Immediate Use Of Zoledronic Acid For Postmenopausal Patients With Early Breast Cancer Who Are Using Adjuvant Letrozole

Phase 3 Unknown

Breast Neoplasms

NCT03408652 2021-10-22

MOSCAR

Phase 3 Terminated

Carcinoma, Renal Cell

NCT00127205 2021-07-02

S0307 Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer.

Phase 3 Completed

6,097 enrolled 20 charts

Breast Neoplasms

NCT00058188 2020-12-08

Zolendronate for the Prevention of Bone Loss in Men w/ Prostate CA on Long-Term Androgen Deprivation

Phase 3 Terminated

Osteoporosis, Prostatic Neoplasms

NCT00079001 2020-05-12

Zoledronate in Preventing Skeletal (Bone)-Related Events in Men Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone Metastases

Phase 3 Completed

645 enrolled 13 charts

Neoplasm Metastasis, Prostatic Neoplasms

NCT01099436 2020-01-21

NEO-ZOTAC

Phase 3 Completed

Breast Neoplasms

NCT00987636 2019-10-22

EWING2008

Phase 3 Completed

Neoplasm Metastasis, Sarcoma, Ewing

NCT00130494 2019-04-16

Zoledronic Acid Administration to Metastatic Breast Cancer Patients With Non-symptomatic Bone Lesions

Phase 3 Terminated

Breast Neoplasms, Neoplasm Metastasis

NCT00869206 2018-11-07

Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement

Phase 3 Completed

1,822 enrolled 19 charts

BreastGenitourinaryPlasma cell

Breast Neoplasms, Multiple Myeloma, Pain, Prostatic Neoplasms

NCT00321620 2018-08-29

Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Men With Hormone-refractory Prostate Cancer

Phase 3 Completed

1,904 enrolled 15 charts

Fractures, Bone

NCT00329797 2017-11-29

Zoledronate in Preventing Osteoporosis and Bone Fractures in Patients With Locally Advanced Nonmetastatic Prostate Cancer Undergoing Radiation Therapy and Hormone Therapy

Phase 3 Completed

109 enrolled 8 charts

Osteoporosis, Prostatic Neoplasms

NCT00193856 2017-10-12

RADAR Trial - Randomised Androgen Deprivation and Radiotherapy

Phase 3 Completed

Prostatic Neoplasms

NCT00086268 2017-09-13

ZPACT

Phase 3 Completed

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00099177 2017-08-16

A Study to Assess the Efficacy of Intravenous/Oral Bondronat (Ibandronate) in Patients With Metastatic Bone Disease Experiencing Moderate to Severe Pain

Phase 3 Terminated

Bone Neoplasms, Neoplasm Metastasis, Pain

NCT00099203 2017-08-16

A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone Disease

Phase 3 Terminated

Bone Neoplasms, Neoplasm Metastasis, Pain

NCT02622607 2017-07-21

Preventive Effects of Zoledronic Acid on Bone Metastasis in Patients With Stage IIIB and IV Lung Cancer

Phase 3 Unknown

Lung Neoplasms

NCT00375648 2017-06-02

TRAPEZE

Phase 3 Completed

Neoplasms, Pain, Prostatic Neoplasms

NCT00172055 2017-03-06

Study to Assess Efficacy and Safety of Zoledronic Acid and the Value of Markers of Bone Resorption in the Prediction of Bone Metastases and Cancer Treatment-induced Bone Loss (CTIBL) in Patients With Prostate Cancer on Hormone Therapy

Phase 3 Completed

Osteoporosis, Prostatic Neoplasms

NCT00171639 2017-02-23

The Use of Zoledronic Acid in Men on Androgen Deprivation Therapy for Prostate Cancer With Preexisting Osteoporosis

Phase 3 Completed

Prostatic Neoplasms

NCT01920568 2017-01-16

A Study to Compare Denosumab With Zoledronic Acid in Subjects With Bone Metastases From Solid Tumors

Phase 3 Completed

487 enrolled 13 charts

Fractures, Bone

NCT00107263 2016-12-06

Zoledronate in Preventing Bone Loss in Postmenopausal Women Who Are Receiving Letrozole for Stage I, Stage II, or Stage IIIA Breast Cancer

Phase 3 Completed

Breast Neoplasms, Osteoporosis

NCT02739594 2016-07-22

COMPARE

Phase 3 Terminated

89 enrolled 17 charts

Multiple Myeloma

NCT00022087 2016-07-19

Zoledronate, Calcium, and Vitamin D in Preventing Bone Loss in Women Receiving Adjuvant Chemotherapy for Breast Cancer

Phase 3 Completed

Breast Neoplasms, Osteoporosis

NCT02595138 2015-11-03

Zoledronic Acid as Adjuvant Treatment of Triple-negative Breast Cancer

Phase 3 Unknown

Triple Negative Breast Neoplasms

NCT00685646 2015-10-16

ZAPCA

Phase 3 Completed

Neoplasm Metastasis, Prostatic Neoplasms

NCT00172042 2015-05-04

A Study to Evaluate the Safety and Efficacy of Zoledronic Acid in the Prevention or Delaying of Bone Metastasis in Patients With Stage IIIA and IIIB Non-small Cell Lung Cancer (NSCLC)

Phase 3 Completed

437 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung

NCT00512993 2015-03-05

NATAN

Phase 3 Completed

Breast Neoplasms

NCT00320710 2014-08-22

Continued Efficacy and Safety of Zoledronic Acid (q 4 Wks vs. q 12 Wks) in the 2nd Year of Treatment in Patients With Bone Metastases From Breast Cancer

Phase 3 Completed

416 enrolled 10 charts

Breast Neoplasms

NCT00242567 2014-05-07

Study of Zoledronic Acid for Patients With Hormone-sensitive Bone Metastases From Prostate Cancer

Phase 3 Completed

522 enrolled 8 charts

Prostatic Neoplasms

NCT00712985 2014-04-24

CTIBL

Phase 3 Completed

18 enrolled 5 charts

Breast Neoplasms

NCT00215943 2014-04-17

Phase III Randomized Trial of Thalidomide/Dexamethasone Versus Vincristine+Adriamycin+Dexamethasone (VAD)

Phase 3 Terminated

90 enrolled 10 charts

Other hematologic neoplasmPlasma cell

Multiple Myeloma, Hematologic Neoplasms

NCT00033332 2014-04-04

Dexamethasone With or Without Thalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma

Phase 3 Completed

Multiple Myeloma, Neoplasms, Plasma Cell

NCT00049452 2014-01-06

Zoledronate in Preventing Bone Loss in Premenopausal Women Receiving Chemotherapy After Surgery For Early Stage Breast Cancer

Phase 3 Completed

Breast Neoplasms, Osteoporosis

NCT00301886 2013-11-13

S0308 Zoledronate or Ibandronate in Preventing Bone Problems in Women With Stage IV Breast Cancer That Has Spread to the Bone

Phase 3 Withdrawn

Humoral Hypercalcemia Of Malignancy, Breast Neoplasms, Neoplasm Metastasis, Pain

NCT00072020 2013-08-02

Chemotherapy and/or Hormone Therapy With or Without Zoledronate in Treating Women With Stage II or Stage III Breast Cancer

Phase 3 Unknown

Breast Neoplasms, Neoplasm Metastasis

NCT00352846 2013-07-02

Effect of Zoledronic Acid on Chemotherapy Induced Bone Loss

Phase 3 Completed

135 enrolled 4 charts

Bone Diseases, Metabolic, Lymphoma, Lymphoma, Non-Hodgkin

NCT00005073 2013-05-01

Zoledronate Plus Standard Therapy Compared With Placebo Plus Standard Therapy to Prevent Bone Metastases in Patients With Recurrent Prostate Cancer That Has No Symptoms

Phase 3 Terminated

Prostatic Neoplasms

NCT00326820 2013-03-13

Ibandronate or Zoledronate in Treating Patients With Newly Diagnosed Bone Metastases From Breast Cancer

Phase 3 Unknown

Humoral Hypercalcemia Of Malignancy, Breast Neoplasms, Neoplasm Metastasis, Breast Neoplasms, Male

NCT00003884 2013-02-21

Zoledronate in Treating Patients With Solid Tumors That Have Spread to the Bone

Phase 3 Completed

Humoral Hypercalcemia Of Malignancy, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Pain, Small Cell Lung Carcinoma

NCT00432458 2012-07-04

Zoledronate With or Without Thalidomide in Treating Patients With Early Stage Multiple Myeloma

Phase 3 Completed

68 enrolled 16 charts

Multiple Myeloma, Neoplasms, Plasma Cell