Clinical Trials Browser

Completed × Interventional × abemaciclib × Clear all

NCT03643510 2026-03-16

Evaluating Cancer Response to Treatment With Abemaciclib and Fulvestrant in Women With Recurrent Endometrial Cancer

Phase 2 Completed

Adenocarcinoma of Endometrium

NCT04391595 2026-03-06

LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients

Phase EARLY_PHASE1 Completed

Glioblastoma, Glioma

NCT05999968 2026-03-05

Abemaciclib Plus Darolutamide in Prostate Cancer That Has Spread After Initial Treatment

Phase 1 Completed

Prostatic Neoplasms

NCT04238819 2026-03-02

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Phase 1/2 Completed

47 enrolled 36 charts

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT04481113 2026-01-29

Abemaciclib and Niraparib Before Surgery for the Treatment of Hormone Receptor Positive HER2 Negative Breast Cancer

Phase 1 Completed

Unilateral Breast Neoplasms

NCT04603183 2025-12-12

ABIGAIL

Phase 2 Completed

Breast Cancer Metastatic

NCT03280563 2025-11-10

MORPHEUS HR+BC

Phase 1/2 Completed

144 enrolled 25 charts

Breast Neoplasms

NCT04627064 2025-07-25

ABEMA Alone or in COMBO With MK-6482

Phase 1 Completed

11 enrolled 9 charts

Carcinoma, Renal Cell

NCT04352777 2025-07-20

Impact of Endocrine Therapy and Abemaciclib on Host and Tumor Immune Cell Repertoire/Function in Advanced ER+/HER2- Breast Cancer

Phase 2 Completed

Breast Neoplasms

NCT03099174 2025-06-24

This Study in Patients With Different Types of Cancer (Solid Tumours) Aims to Find a Safe Dose of Xentuzumab in Combination With Abemaciclib With or Without Hormonal Therapies. The Study Also Tests How Effective These Medicines Are in Patients With Lung and Breast Cancer

Phase 1 Completed

133 enrolled 26 charts

Breast Neoplasms, Neoplasms

NCT04552769 2025-06-05

Abemaciclib in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer

Phase 2 Completed

9 enrolled 10 charts

EndocrineHead & Neck

Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT03732703 2025-02-14

MyDRUG

Phase 1/2 Completed

Multiple Myeloma

NCT04432454 2025-02-13

ELAINEII

Phase 2 Completed

Breast Neoplasms

NCT02675231 2024-11-26

monarcHER

Phase 2 Completed

237 enrolled 25 charts

Hormone Receptor Positive Breast Cancer

NCT02791334 2024-09-27

PACT

Phase 1 Completed

BreastDermatologicGastrointestinal

Breast Neoplasms, Melanoma, Pancreatic Neoplasms

NCT01394016 2024-09-19

A Phase 1 Study of LY2835219 In Participants With Advanced Cancer

Phase 1 Completed

225 enrolled 31 charts

Advanced Cancer

NCT04408924 2024-06-25

CYCLONE 1

Phase 2 Completed

44 enrolled 21 charts

Metastatic Castration-Resistant Prostate Cancer

NCT03703466 2024-04-02

A Study of Abemaciclib (LY2835219) With and Without Food in Participants With Metastatic Breast Cancer

Phase 2 Completed

72 enrolled 19 charts

Breast Neoplasms

NCT03339843 2024-03-15

MiMe-A

Phase 2 Completed

GastrointestinalGenitourinaryGynecologic

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Neoplasms, Urologic Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT02644460 2023-10-26

AflacST1501

Phase 1 Completed

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Neuroblastoma, Recurrence, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT01739309 2023-09-21

Study of LY2835219 for Mantle Cell Lymphoma

Phase 2 Completed

28 enrolled 20 charts

Lymphoma, Non-Hodgkin, Lymphoma, Mantle-Cell

NCT03356223 2023-02-23

ABORL

Phase 2 Completed

Head and Neck Neoplasms, Neoplasm Metastasis

NCT04514159 2023-02-01

A Study of ZN-c5 and Abemaciclib in Participants With Breast Cancer

Phase 1 Completed

Breast Neoplasms

NCT02857270 2022-11-22

A Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic Cancer

Phase 1 Completed

DermatologicGastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma, Colorectal Neoplasms

NCT02688088 2022-10-18

A Study of Abemaciclib in Participants With Cancer That is Advanced or Has Spread to Another Part(s) of the Body

Phase 1 Completed

48 enrolled 30 charts

Neoplasm Metastasis

NCT01655225 2022-04-08

A Study of LY3023414 in Participants With Advanced Cancer

Phase 1 Completed

BreastLymphoidOther solid neoplasmThoracic

Mesothelioma, Malignant, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lymphoma, Lymphoma, Non-Hodgkin, Mesothelioma, Neoplasm Metastasis

NCT03292250 2022-03-29

Korean Cancer Study Group: Translational bIomarker Driven UMbrella Project for Head and Neck (TRIUMPH), Esophageal Squamous Cell Carcinoma- Part 1 (HNSCC)]

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04071262 2021-09-21

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Therapies in Japanese Participants With Advanced Cancer

Phase 1 Completed

Advanced Cancer

NCT02450539 2021-08-13

A Study of Abemaciclib (LY2835219) in Participants With Stage IV Squamous Non-small Cell Lung Cancer

Phase 2 Completed

159 enrolled 22 charts

Carcinoma, Non-Small-Cell Lung

NCT02919696 2020-09-25

A Study of Abemaciclib (LY2835219) in Native Chinese Participants With Advanced and/or Metastatic Cancers

Phase 1 Completed

26 enrolled 16 charts

Neoplasm Metastasis

NCT02079636 2020-09-11

A Study of Abemaciclib (LY2835219) in Combination With Another Anti-cancer Drug in Participants With Lung Cancer (NSCLC)

Phase 1 Completed

142 enrolled 36 charts

Carcinoma, Non-Small-Cell Lung

NCT02014129 2020-08-24

A Study of LY2835219 in Japanese Participants With Advanced Cancer

Phase 1 Completed

12 enrolled 11 charts

Lymphoma, Neoplasm Metastasis

NCT02441946 2020-06-17

neoMONARCH

Phase 2 Completed

224 enrolled 20 charts

Breast Neoplasms

NCT02102490 2020-01-21

MONARCH 1

Phase 2 Completed

132 enrolled 17 charts 1 FDA

Breast Neoplasms

NCT02981342 2019-11-20

A Study of Abemaciclib (LY2835219) Alone or in Combination With Other Agents in Participants With Previously Treated Pancreatic Ductal Adenocarcinoma

Phase 2 Completed

106 enrolled 24 charts

Gastrointestinal

Pancreatic Neoplasms

NCT02117648 2019-01-07

A Study of LY2835219 in Participants With Cancer

Phase 1 Completed

26 enrolled 11 charts

Neoplasm Metastasis, Neoplasms