Clinical Trials Browser

Colorectal Neoplasms

NCT01652196 2025-02-05

Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer

Phase 2 Completed

56 enrolled 14 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT02384759 2024-07-10

FOLFA

Phase 2 Completed

117 enrolled 12 charts

Gastrointestinal

Colorectal Neoplasms

NCT00407654 2024-03-04

VEGF Trap in Treating Patients With Previously Treated Metastatic Colorectal Cancer

Phase 2 Completed

75 enrolled 15 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT03530267 2024-02-23

ELDERLY

Phase 2 Completed

124 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT01782443 2023-08-14

Ziv-Aflibercept for Advanced Progressive Carcinoid Tumors

Phase 2 Completed

19 enrolled 11 charts

Endocrine

Carcinoid Tumor, Neoplasm Metastasis

NCT03279289 2023-04-13

AFEMA

Phase 2 Completed

170 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT03043729 2023-02-06

mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer

Phase 2 Completed

119 enrolled

Gastrointestinal

Rectal Neoplasms

NCT02181556 2021-06-07

Efficacy and Safety of Aflibercept in Combination With FOLFIRI Chemotherapy as 1st Line Treatment for Patients With Metastatic Colorectal Cancer

Phase 2 Completed

41 enrolled 8 charts

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT02340949 2021-05-03

RIA

Phase 2 Completed

180 enrolled 15 charts

Gastrointestinal

Rectal Neoplasms

NCT02101918 2020-03-23

Ziv-Aflibercept in Treating and Computed Tomography Perfusion Imaging in Predicting Response in Patients With Pancreatic Neuroendocrine Tumors That Are Metastatic or Cannot Be Removed by Surgery

Phase 2 Completed

22 enrolled 10 charts

Endocrine

Somatostatinoma, Multiple Endocrine Neoplasia Type 1

NCT01747551 2020-02-10

FOLFOX +/- Ziv-Aflibercept for Esophageal and Gastric Cancer

Phase 2 Completed

64 enrolled 11 charts

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT00462826 2019-07-23

VEGF Trap in Treating Patients With Recurrent or Persistent Endometrial Cancer

Phase 2 Completed

49 enrolled 13 charts

Gynecologic

Endometrial Neoplasms

NCT01258855 2019-05-10

Aldesleukin With or Without Ziv-Aflibercept in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

Phase 2 Completed

84 enrolled 13 charts

Dermatologic

Melanoma

NCT00450255 2018-05-24

VEGF Trap in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

Phase 2 Completed

41 enrolled 7 charts

Dermatologic

Uveal Melanoma, Melanoma

NCT02129257 2017-10-24

AMALTHEA

Phase 2 Completed

73 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT00828139 2017-08-21

S0802 - Topotecan With or Without Aflibercept in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Phase 2 Completed

189 enrolled 15 charts

Thoracic

Small Cell Lung Carcinoma

NCT00357760 2017-06-23

Ziv-Aflibercept in Treating Patients With Metastatic or Unresectable Kidney Cancer

Phase 2 Completed

94 enrolled 8 charts

Genitourinary

Carcinoma, Renal Cell

NCT01882868 2017-03-14

A Study of Aflibercept in Combination With FOLFIRI in Patients With Second-Line Metastatic Colorectal Cancer in Japan

Phase 2 Completed

62 enrolled 34 charts

Gastrointestinal

Colorectal Cancer Metastatic

NCT01749956 2017-02-07

5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer

Phase 2 Completed

39 enrolled 13 charts

Gastrointestinal

Rectal Neoplasms

NCT00851084 2016-06-07

AFFIRM

Phase 2 Completed

268 enrolled 16 charts

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00390234 2015-12-07

Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcoma

Phase 2 Completed

63 enrolled 10 charts

Gynecologic

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms

NCT00407485 2014-10-20

VEGF Trap in Treating Patients With Recurrent, Locally Advanced, or Metastatic Cancer of the Urothelium

Phase 2 Completed

22 enrolled 7 charts

Genitourinary

Urinary Bladder Neoplasms, Urethral Neoplasms

NCT00396591 2013-01-10

AVE0005 (VEGF Trap) in Patients With Recurrent Symptomatic Malignant Ascites

Phase 2 Completed

16 enrolled 18 charts

Gynecologic

Ovarian Neoplasms

NCT00284141 2012-12-10

Study of AVE0005 (VEGF Trap) in Locally Advanced or Metastatic Platinum- and Erlotinib- Resistant Non-small-cell-lung Adenocarcinoma

Phase 2 Completed

98 enrolled 14 charts

Thoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung, Disease, Lung Diseases, Lung Neoplasms, Neoplasm Metastasis, Neoplasms

Clinical Trials

SAMCO

Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer

FOLFA

VEGF Trap in Treating Patients With Previously Treated Metastatic Colorectal Cancer

ELDERLY

Ziv-Aflibercept for Advanced Progressive Carcinoid Tumors

AFEMA

mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer

Efficacy and Safety of Aflibercept in Combination With FOLFIRI Chemotherapy as 1st Line Treatment for Patients With Metastatic Colorectal Cancer

RIA

Ziv-Aflibercept in Treating and Computed Tomography Perfusion Imaging in Predicting Response in Patients With Pancreatic Neuroendocrine Tumors That Are Metastatic or Cannot Be Removed by Surgery

FOLFOX +/- Ziv-Aflibercept for Esophageal and Gastric Cancer

VEGF Trap in Treating Patients With Recurrent or Persistent Endometrial Cancer

Aldesleukin With or Without Ziv-Aflibercept in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

VEGF Trap in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

AMALTHEA

S0802 - Topotecan With or Without Aflibercept in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Ziv-Aflibercept in Treating Patients With Metastatic or Unresectable Kidney Cancer

A Study of Aflibercept in Combination With FOLFIRI in Patients With Second-Line Metastatic Colorectal Cancer in Japan

5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer

AFFIRM

Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcoma

VEGF Trap in Treating Patients With Recurrent, Locally Advanced, or Metastatic Cancer of the Urothelium

AVE0005 (VEGF Trap) in Patients With Recurrent Symptomatic Malignant Ascites

Study of AVE0005 (VEGF Trap) in Locally Advanced or Metastatic Platinum- and Erlotinib- Resistant Non-small-cell-lung Adenocarcinoma