Clinical Trials

400 enrolled

Phase 3 Not yet recruiting

Carcinoma, Non-Small-Cell Lung

NCT07472517 2026-03-16

DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy

670 enrolled

Small Cell Lung Carcinoma

NCT05862285 2026-03-13

UmbrellaMAX

100 enrolled

Neoplasms

NCT05047250 2026-03-11

A Study of Atezolizumab in High PD-L1 Expression, Chemotherapy-Naïve Patients With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer

60 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05091567 2026-03-10

IMforte

660 enrolled 23 charts 1 FDA

Small Cell Lung Carcinoma

NCT06646276 2026-03-04

A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

530 enrolled

Small Cell Lung Carcinoma

NCT04660344 2026-02-13

IMvigor011

761 enrolled

Muscle-invasive Bladder Cancer

NCT04665856 2026-02-13

SKYSCRAPER-02C

123 enrolled 26 charts

Small Cell Lung Carcinoma

NCT06712355 2026-02-13

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

621 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT04294810 2026-01-30

SKYSCRAPER-01

620 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04712643 2026-01-30

A Study of TACE Combined With Atezolizumab Plus Bevacizumab or TACE Alone in Patients With Untreated Heaptocellular Carcionma

342 enrolled

Carcinoma, Hepatocellular

NCT03768063 2026-01-29

IMbrella B

1,000 enrolled

Neoplasms

NCT04256421 2026-01-28

SKYSCRAPER-02

490 enrolled 31 charts

Small Cell Lung Carcinoma

NCT03456063 2026-01-22

A Study of Neoadjuvant Atezolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in Patients With Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer (IMpower030)

453 enrolled

Non-Small-Cell Lung

NCT04543617 2026-01-20

SKYSCRAPER-07

760 enrolled

Esophageal Squamous Cell Carcinoma

NCT03148418 2026-01-13

A Study in Participants Previously Enrolled in a Genentech- and/or F. Hoffmann-La Roche Ltd-Sponsored Atezolizumab Study (IMbrella A)

382 enrolled

Neoplasms

NCT06921785 2026-01-09

ARTEMIDE-HCC01

1,220 enrolled

Carcinoma, Hepatocellular

NCT05112965 2026-01-07

An Extension Study in Participants Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study (IMbrella C)

49 enrolled

Neoplasms

NCT05904886 2025-12-31

SKYSCRAPER-14

687 enrolled

Carcinoma, Hepatocellular

NCT04148911 2025-12-26

EL1SSAR

184 enrolled 15 charts

Triple Negative Breast Neoplasms

NCT04446117 2025-12-18

CONTACT-02

575 enrolled 13 charts

Prostatic Neoplasms

NCT03755791 2025-12-11

COSMIC-312

837 enrolled 14 charts

Carcinoma, Carcinoma, Hepatocellular, Neoplasms

NCT05317858 2025-12-10

LIMITLESS

30 enrolled

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT03735121 2025-12-05

A Study to Investigate Atezolizumab Subcutaneous in Patients With Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

438 enrolled 40 charts 1 FDA

Carcinoma, Non-Small-Cell Lung

NCT03371017 2025-11-12

IMpassion132

595 enrolled 37 charts

Triple Negative Breast Neoplasms

NCT04540211 2025-10-28

SKYSCRAPER-08

461 enrolled

Esophageal Neoplasms

NCT05468489 2025-10-21

To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in US Patients With ES-SCLC

200 enrolled

Extensive Stage Small Cell Lung Cancer

NCT03520686 2025-10-16

Nogapendekin Alfa Inbakicept for Advanced Non-Small Cell Lung Cancer

1,538 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04487067 2025-09-22

AMETHISTA

152 enrolled 16 charts

Carcinoma, Hepatocellular

NCT04513925 2025-09-08

SKYSCRAPER-03

829 enrolled

Phase 3 Not yet recruiting

Carcinoma, Non-Small-Cell Lung

NCT06680258 2025-09-03

A Study of TPST-1120 With Atezolizumab Plus Bevacizumab in Patients With Unresectable or Metastatic HCC Not Previously Treated With Systemic Therapy

740 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasm Metastasis

NCT04740918 2025-08-08

KATE3

96 enrolled 16 charts

Breast Neoplasms

NCT02908672 2025-07-20

A Study of Atezolizumab Plus Cobimetinib and Vemurafenib Versus Placebo Plus Cobimetinib and Vemurafenib in Previously Untreated BRAFv600 Mutation-Positive Patients With Metastatic or Unresectable Locally Advanced Melanoma

514 enrolled 25 charts 2 FDA

Dermatologic

Melanoma

NCT04732286 2025-05-08

A Study of Atezolizumab in Combination With Bevacizumab in Spanish Patients With Unresectable or Unsuitable for Locoregional Treatments Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy

100 enrolled 18 charts

Carcinoma, Hepatocellular

NCT03353831 2025-04-06

Atezolizumab With Bevacizumab and Chemotherapy vs Bevacizumab and Chemotherapy in Early Relapse Ovarian Cancer

574 enrolled

Gynecologic

Ovarian Neoplasms

NCT04338269 2025-04-04

CONTACT-03

522 enrolled 18 charts

Carcinoma, Renal Cell

NCT02807636 2025-02-24

IMvigor130

1,213 enrolled 35 charts

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT03726879 2024-11-05

IMpassion050

454 enrolled 28 charts

Breast Neoplasms

NCT03191786 2024-10-23

IPSOS

453 enrolled 20 charts

Carcinoma, Non-Small-Cell Lung

NCT03016312 2024-08-09

IMbassador250

759 enrolled 22 charts

Prostatic Neoplasms, Castration-Resistant

NCT04194203 2024-07-19

A Study of Bevacizumab, Carboplatin, and Paclitaxel or Pemetrexed With or Without Atezolizumab in Chemotherapy-Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer (IMpower151)

305 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04028050 2024-07-16

MAURIS

155 enrolled

Small Cell Lung Carcinoma

NCT04177108 2024-03-27

A Study of Ipatasertib in Combination With Atezolizumab and Paclitaxel as a Treatment for Participants With Locally Advanced or Metastatic Triple-Negative Breast Cancer

242 enrolled 12 charts

Breast Diseases, Breast Neoplasms, Neoplasms, Neoplasms by Site, Skin Diseases, Triple Negative Breast Neoplasms

NCT02657434 2023-11-21

A Study of Atezolizumab in Combination With Carboplatin or Cisplatin + Pemetrexed Compared With Carboplatin or Cisplatin + Pemetrexed in Participants Who Are Chemotherapy-Naive and Have Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (IMpower 132)

578 enrolled 22 charts

Carcinoma, Non-Small-Cell Lung

NCT03197935 2023-10-26

IMpassion031

333 enrolled 18 charts

Triple Negative Breast Neoplasms

NCT03434379 2023-10-23

IMbrave150

558 enrolled 48 charts 2 FDA

Carcinoma, Hepatocellular

NCT03024996 2023-08-03

IMmotion010

778 enrolled 19 charts

Carcinoma, Renal Cell

NCT02763579 2023-07-28

IMpower133

503 enrolled 23 charts 1 FDA

Small Cell Lung Carcinoma

NCT02450331 2023-06-18

IMvigor010

809 enrolled 19 charts

Carcinoma, Transitional Cell

NCT02409342 2023-03-15

A Study of Atezolizumab (MPDL3280A) Compared With a Platinum Agent (Cisplatin or Carboplatin) + (Pemetrexed or Gemcitabine) in Participants With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower110]

572 enrolled 32 charts 2 FDA