Clinical Trials Browser

Terminated × Interventional × bintrafusp alfa protein, human × Clear all

NCT04789668 2026-03-18

Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

Phase 1/2 Terminated

8 enrolled 13 charts

BreastCNSDermatologicOther hematologic neoplasmThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Hematologic Neoplasms, Triple Negative Breast Neoplasms

NCT04396535 2025-11-17

Docetaxel With or Without Bintrafusp Alfa for the Treatment of Advanced Non-small Cell Lung Cancer

Phase 2 Terminated

10 enrolled 17 charts

Lung Neoplasms

NCT04220775 2024-11-07

Bintrafusp Alfa and Stereotactic Body Radiation Therapy for the Treatment of Recurrent or Second Primary Head and Neck Squamous Cell Cancer

Phase 1/2 Terminated

3 enrolled 8 charts

Squamous Cell Carcinoma of Head and Neck

NCT04349280 2024-04-18

A Study to Evaluate the Efficacy and Safety of Bintrafusp Alfa (M7824) Monotherapy in Metastatic or Locally Advanced Urothelial Cancer

Phase 1 Terminated

25 enrolled 10 charts

Neoplasms

NCT04971187 2023-08-01

Bintrafusp Alfa With Chemotherapy for Tyrosine Kinase Inhibitor-Resistant EGFR-Mutant Non-small Cell Lung Cancer

Phase 2 Terminated

3 enrolled 8 charts

Lung Neoplasms

NCT04489940 2023-04-10

Bintrafusp Alfa in High Mobility Group AT-Hook 2 (HMGA2) Expressing Triple Negative Breast Cancer

Phase 2 Terminated

11 enrolled 9 charts

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT04297748 2023-01-17

Bioimaging Study of 89Zr-M7824 in NSCLC

Phase 1/2 Terminated

Carcinoma, Non-Small-Cell Lung, Camurati-Engelmann Syndrome

NCT04560686 2022-07-28

Bintrafusp Alfa Before Surgery for the Treatment of Untreated Resectable Non-small Cell Lung Cancer

Phase 2 Terminated

2 enrolled 7 charts

Lung Neoplasms

NCT04327986 2022-05-18

Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Advanced Pancreas Cancer

Phase 1/2 Terminated

3 enrolled 13 charts

Gastrointestinal

Pancreatic Neoplasms

NCT04428047 2022-04-06

ICING

Phase 2 Terminated

Squamous Cell Carcinoma of Head and Neck

NCT04296942 2022-01-11

BN-Brachyury, Entinostat, Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT)

Phase 1 Terminated

1 enrolled 10 charts

Breast Neoplasms, Triple Negative Breast Neoplasms