NCT03333343 2026-01-16Study of EGF816 in Combination With Selected Targeted Agents in EGFR-mutant NSCLCNovartisPhase 1 Active not recruiting105 enrolled
NCT01324479 2020-12-19Study of INC280 in Patients With c-MET Dependent Advanced Solid TumorsNovartisPhase 1 Completed131 enrolled
NCT01546428 2020-12-19A Phase I Study of INC280 in Japanese Patients With Advanced Solid TumorsNovartisPhase 1 Completed44 enrolled
NCT02474537 2020-12-10INC280 in Healthy Subjects With Impaired Hepatic Function and Subjects With Normal Hepatic FunctionNovartisPhase 1 Completed31 enrolled
NCT02520752 2020-12-10A DDI Study to Assess the Effect of INC280 on the PK of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid TumorsNovartisPhase 1 Completed37 enrolled
NCT02626234 2020-12-10A Drug-drug Interaction (DDI) Study to Assess the Effect of INC280 on the Pharmacokinetics of Digoxin and Rosuvastatin in Patients With cMET-dysregulated Advanced Solid TumorsNovartisPhase 1 Completed32 enrolled
NCT02205398 2019-01-22Study of Safety and Efficacy of INC280 and Cetuximab, in Adult c-MET Positive mCRC and HNSCC Patients After Progression on Cetuximab or Panitumumab TherapyNovartisPhase 1 Terminated13 enrolled
NCT01072266 2017-11-22A Dose-escalation Study in Subjects With Advanced MalignanciesIncyte CorporationPhase 1 Completed45 enrolled