Clinical Trials Browser

Phase 2 × NIH × cixutumumab × Clear all

NCT01142388 2025-11-25

Paclitaxel With or Without Cixutumumab as Second-Line Therapy in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer

Phase 2 Active not recruiting

94 enrolled 8 charts

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT00887159 2021-01-05

A Randomized Phase II Study of Cisplatin and Etoposide in Combination With Either Hedgehog Inhibitor GDC-0449 or IGF-1R MOAB IMC-A12 for Patients With Extensive Stage

Phase 2 Completed

168 enrolled 11 charts

Small Cell Lung Carcinoma

NCT00684983 2020-03-24

Capecitabine and Lapatinib Ditosylate With or Without Cixutumumab in Treating Patients With Previously Treated HER2-Positive Stage IIIB-IV Breast Cancer

Phase 2 Completed

64 enrolled 13 charts

Insulin-Like Growth Factor I, Resistance To, Breast Neoplasms

NCT01413191 2020-02-19

Cixutumumab in Treating Patients With Metastatic Melanoma of the Eye

Phase 2 Completed

18 enrolled 9 charts

Uveal Melanoma

NCT01614795 2018-12-11

Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma

Phase 2 Completed

46 enrolled 13 charts

Fibrosarcoma, Hemangiosarcoma, Liposarcoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00955305 2018-06-06

Paclitaxel, Carboplatin, and Bevacizumab With or Without Cixutumumab in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer

Phase 2 Terminated

175 enrolled 8 charts

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung

NCT01160458 2018-04-10

Phase II Study of IMC-A12 in Patients With Mesothelioma Who Have Been Previously Treated With Chemotherapy

Phase 2 Completed

20 enrolled 12 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT01120236 2018-02-26

Bicalutamide and Goserelin or Leuprolide Acetate With or Without Cixutumumab in Treating Patients With Newly Diagnosed Metastatic Prostate Cancer

Phase 2 Completed

211 enrolled 17 charts

Prostatic Neoplasms

NCT01055314 2017-08-29

Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma

Phase 2 Completed

175 enrolled 13 charts

Rhabdomyosarcoma, Sarcoma

NCT01016015 2015-07-30

Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone Sarcoma

Phase 2 Completed

178 enrolled 6 charts

Sarcoma, Osteosarcoma

NCT00831844 2015-03-30

Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors

Phase 2 Completed

116 enrolled 8 charts

CNSEndocrineGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Neuroectodermal Tumors, Hepatoblastoma, Adrenocortical Carcinoma

NCT00986674 2014-09-26

Carboplatin and Paclitaxel Combined With Cetuximab and/or IMC-A12 in Patients With Advanced Non-Small Cell Lung Cancer

Phase 2 Completed

140 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung

NCT00639509 2014-05-23

IMC-A12 in Treating Patients With Advanced Liver Cancer

Phase 2 Completed

24 enrolled 8 charts

Gastrointestinal

Carcinoma, Hepatocellular

NCT00778817 2014-04-29

IMC-A12 With Mitotane vs Mitotane Alone in Recurrent, Metastatic, or Primary ACC That Cannot Be Removed by Surgery

Phase 2 Terminated

20 enrolled 17 charts

Adrenocortical Carcinoma