Clinical Trials

189 enrolled 24 charts

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT03946800 2024-10-02

A Study of MEDI1191 in Sequential and Concurrent Combination With Durvalumab in Subjects With Advanced Solid Tumors

61 enrolled

Tumor-Agnostic

Neoplasms

NCT02454933 2024-09-19

CAURAL

29 enrolled 10 charts

Locally Advanced or Metastatic EGFR T790M+ NSCLC

NCT02616640 2024-09-19

A Study to Determine Dose and Regimen of Durvalumab as Monotherapy or in Combination With Pomalidomide With or Without Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma

114 enrolled

Plasma cell

Multiple Myeloma, Recurrence

NCT04385368 2024-08-30

MERMAID-1

89 enrolled 10 charts

Carcinoma, Non-Small-Cell Lung

NCT03421353 2024-08-21

AZD9150 Plus Durvalumab Alone or in Combination With Chemotherapy in Patients With Advanced, Solid Tumours and in Patients With Non-Small-Cell Lung Cancer

76 enrolled

Advanced Solid Tumours

NCT02352948 2024-07-26

ARCTIC

597 enrolled 23 charts

Non - Small Cell Lung Cancer NSCLC

NCT03830866 2024-07-26

CALLA

770 enrolled 12 charts

Gynecologic

Locally Advanced Cervical Cancer

NCT04642469 2024-06-25

MERMAID-2

30 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03693300 2024-06-18

A Study to Determine Safety of Durvalumab After Sequential Chemo Radiation in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

117 enrolled 16 charts

Carcinoma, Non-Small-Cell Lung

NCT02937818 2024-06-07

A Phase II, Study to Determine the Preliminary Efficacy of Novel Combinations of Treatment in Patients With Platinum Refractory Extensive-Stage Small-Cell Lung Cancer

72 enrolled 29 charts

Platinum Refractory Extensive-Stage Small Cell Lung Carcinoma

NCT03238027 2024-05-17

A Phase 1 Study to Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors

45 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT04089553 2024-04-16

An Open-label, Phase II Study of AZD4635 in Patients With Prostate Cancer

59 enrolled 19 charts

Genitourinary

Prostatic Neoplasms

NCT03310619 2024-04-04

PLATFORM

62 enrolled 41 charts

Lymphoid

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoma, Large B-Cell, Diffuse

NCT02879617 2024-01-05

A Clinical Trial of Durvalumab (MEDI4736) as 1st Line Therapy in Advanced Non-small Cell Lung Cancer Patients

47 enrolled 34 charts

Non-Small Cell Lung Cancer NSCLC

NCT02527434 2023-11-15

Study of Tremelimumab in Patients With Advanced Solid Tumors

64 enrolled 22 charts

Breast

Triple Negative Breast Neoplasms

NCT02718911 2023-10-16

A Study of LY3022855 in Combination With Durvalumab or Tremelimumab in Participants With Advanced Solid Tumors

72 enrolled 23 charts

Solid Tumor

NCT02125461 2023-10-10

PACIFIC

713 enrolled 23 charts 1 FDA

Carcinoma, Non-Small-Cell Lung

NCT02685826 2023-10-06

A Study of Durvalumab in Combination With Lenalidomide With and Without Dexamethasone in Adults With Newly Diagnosed Multiple Myeloma

56 enrolled 38 charts

Plasma cell

Multiple Myeloma

NCT03611556 2023-10-03

MEDI9447(Oleclumab) Pancreatic Chemotherapy Combination Study.

213 enrolled 42 charts

Gastrointestinal

Carcinoma, Pancreatic Neoplasms

NCT04667312 2023-10-02

CODAK

Completed

115 enrolled

Non-Small Cell Lung Cancer NSCLC

NCT05933044 2023-09-05

RELEVANCE

Completed

662 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04495179 2023-08-09

AARDVARC

30 enrolled 22 charts

Genitourinary

Prostatic Neoplasms

NCT02503774 2023-07-11

MEDI9447 Alone and in Combination With MEDI4736 in Adult Participants With Select Advanced Solid Tumors.

192 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02775903 2023-02-28

An Efficacy and Safety Study of Azacitidine Subcutaneous in Combination With Durvalumab (MEDI4736) in Previously Untreated Adults With Higher-Risk Myelodysplastic Syndromes (MDS) or in Elderly Patients With Acute Myeloid Leukemia (AML)

MyeloidOther hematologic neoplasm

213 enrolled 35 charts

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT03889275 2023-02-21

A Study of MEDI5395 in Combination With Durvalumab in Participants With Select Advanced Solid Tumors

39 enrolled

Advanced Solid Tumors

NCT03084471 2022-12-22

STRONG

867 enrolled 10 charts

Diabetes Mellitus, Insulin-Dependent, 12

NCT04261075 2022-08-15

IPH5201 as Monotherapy or in Combination With Durvalumab +/- Oleclumab in Subjects With Advanced Solid Tumors.

57 enrolled

Advanced Solid Tumors

NCT02088112 2022-04-04

MEDI4736 (Anti PD-L1) Combined With Gefitinib in Subjects With Non-Small Cell Lung Cancer(NSCLC).

56 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02318277 2022-01-13

A Study of Epacadostat (INCB024360) in Combination With Durvalumab (MEDI4736) in Subjects With Selected Advanced Solid Tumors (ECHO-203)

176 enrolled 25 charts

Head & NeckThoracic

Head and Neck Neoplasms, Lung Neoplasms

NCT02978482 2021-08-18

A Phase 1/2 Study of Durvalumab(MEDI4736) and Tremelimumab in Chinese Patients With Advanced Malignancies

26 enrolled

Advanced Malignancy

NCT02118337 2021-06-01

A Phase 1/2, Open-label Study to Evaluate the Safety and Antitumor Activity of MEDI0680 (AMP-514) in Combination With Durvalumab Versus Nivolumab Monotherapy in Participants With Select Advanced Malignancies

97 enrolled 40 charts

Genitourinary

Carcinoma, Renal Cell, Kidney Neoplasms

NCT01938612 2021-03-12

A Phase I, Open-Label, Multicentre Study to Evaluate the Safety, Tolerability and Pharmacokinetics of MEDI4736 in Patients With Advanced Solid Tumours

GastrointestinalHead & Neck

269 enrolled

Squamous Cell Carcinoma of Head and Neck, Biliary Tract Neoplasms

NCT02369874 2021-02-10

EAGLE

736 enrolled 26 charts

Head & Neck

Head and Neck Neoplasms, Recurrence

NCT02572687 2021-01-20

A Study of Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies

85 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Neoplasm Metastasis, Stomach Neoplasms

NCT02900157 2021-01-14

Study to Evaluate the Safety and Pharmacokinetics of MEDI9090 in Subjects With Advanced Solid Tumors

42 enrolled

Advanced Solid Tumors

NCT02423863 2020-12-17

Poly-ICLC

DermatologicHead & NeckSarcoma

26 enrolled

Head and Neck Neoplasms, Melanoma, Neoplasms, Sarcoma

NCT02207530 2020-09-29

Phase II Study of MEDI4736 Monotherapy in Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck