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Phase 2 1 Phase 1 1

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Interventional 1

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Conditions

Neoplasms 1 Hearing Loss 1

Interventions

Cyclophosphamide 571 pembrolizumab 442 Paclitaxel 410 Gemcitabine 394 Cisplatin 389 Carboplatin 388 Radiotherapy 347 fludarabine 324 Nivolumab 305 Bevacizumab 252 Docetaxel 247 Irinotecan 232 Magnetic Resonance Spectroscopy 217 Fluorouracil 203 Dexamethasone 201 Capecitabine 197 Specimen Handling 196 Rituximab 188 Cytarabine 183 Oxaliplatin 182 Temozolomide 179 fludarabine phosphate 176 Biopsy 175 Ipilimumab 172 Etoposide 166 Lenalidomide 162 Leucovorin 155 Doxorubicin 155 Cetuximab 154 Bortezomib 152

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30 days 90 days 1 year All

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NCT01452607 2016-06-29

Study to Evaluate the Safety and Pharmacokinetics of SPI-1005

Sound Pharmaceuticals, Incorporated

Phase 1 Completed

Neoplasms, Hearing Loss

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