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Phase 2 1 Phase 1 1

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Interventional 1

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Conditions

Neoplasms 1 Hearing Loss 1

Interventions

pembrolizumab 261 Paclitaxel 185 Carboplatin 181 Gemcitabine 151 Cisplatin 129 Cyclophosphamide 127 Docetaxel 123 Nivolumab 117 Bevacizumab 108 Injections 95 fludarabine 87 atezolizumab 81 Pemetrexed 81 Dexamethasone 81 Cetuximab 81 Fluorouracil 73 Irinotecan 68 venetoclax 66 Capecitabine 65 Rituximab 64 Azacitidine 60 130-nm albumin-bound paclitaxel 58 Leucovorin 55 Trastuzumab 51 Lenalidomide 51 Oxaliplatin 50 Ipilimumab 50 Fulvestrant 50 Midazolam 49 durvalumab 48

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30 days 90 days 1 year All

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NCT01452607 2016-06-29

Study to Evaluate the Safety and Pharmacokinetics of SPI-1005

Sound Pharmaceuticals, Incorporated

Phase 1 Completed

Neoplasms, Hearing Loss

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