Clinical Trials Browser

Phase 1 × OTHER × irinotecan sucrosofate × Clear all

NCT07104604 2025-08-08

Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Toripalimab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal Involvement

Phase 1 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT07060014 2025-07-11

NALIRIFOX (Nal-IRI Plus 5-FU/LV Plus Oxaliplatin) as First-Line Treatment for Patients With Advanced Small Intestine and Appendiceal Cancers

Phase 1 Not yet recruiting

Gastrointestinal

Advanced Small Intestine Cancer

NCT05277766 2025-07-01

PIPAC-NAL-IRI

Phase 1 Recruiting

GastrointestinalGynecologic

Appendiceal Neoplasms, Bile Duct Neoplasms, Pancreatic Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT05049863 2024-12-05

Chemotherapy in Patients With Relapsed Small Cell Lung Cancer in Combination With Allopurinol and MycoPhenolate (CLAMP Trial)

Phase 1 Terminated

Small Cell Lung Carcinoma

NCT06710821 2024-11-29

Irinotecan Liposomes Combined with Temozolomide and Vincristine in the Treatment of Pediatric Patients with Solid Tumors

Phase 1 Not yet recruiting

Other solid neoplasm

Solid Tumor Cancer

NCT06225622 2024-03-19

Dose Escalation and Expansion Clinical Trial of Irinotecan Liposome Combined With Oxaliplatin and 5-FU/LV Plus Bevacizumab as First-line Treatment of Metastatic Colorectal Cancer

Phase 1 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT02022644 2023-06-29

Study of Convection-Enhanced, Image-Assisted Delivery of Liposomal-Irinotecan In Recurrent High Grade Glioma

Phase 1 Completed

Glioma

NCT03086616 2023-04-06

CED With Irinotecan Liposome Injection Using Real Time Imaging in Children With Diffuse Intrinsic Pontine Glioma (DIPG) (PNOC 009)

Phase 1 Completed

Diffuse Intrinsic Pontine Glioma, Glioma

NCT04088786 2022-05-06

Phase I Trial HIPEC With Nal-irinotecan

Phase 1 Completed

GastrointestinalOther solid neoplasmThoracic

Adenocarcinoma, Mucinous, Mesothelioma, Pseudomyxoma Peritonei, Stomach Neoplasms, Colorectal Neoplasms, Neoplasms, Cystic, Mucinous, and Serous

NCT03703063 2021-01-27

Alternative Neoadjuvant Chemotherapy in Resectable and Borderline Resectable Pancreatic Cancer

Phase 1 Unknown

Gastrointestinal

Pancreatic Neoplasms

NCT03207724 2020-12-30

OnFX

Phase 1 Completed

Gastrointestinal

Adenocarcinoma, Cachexia, Disease, Pancreatic Neoplasms, Weight Loss

NCT00062842 2020-03-04

Study of Irinotecan on a Weekly Schedule in Children

Phase 1 Completed

Neoplasms

NCT02640365 2017-01-31

DOUBLIRI

Phase 1 Completed

Neoplasms

NCT00734682 2015-01-07

A Phase I Trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients With Recurrent High-Grade Gliomas

Phase 1 Completed

Astrocytoma, Glioblastoma, Oligodendroglioma, Gliosarcoma