Clinical Trials Browser

Phase 1 × Interventional × midostaurin × Clear all

NCT03900949 2025-10-28

Gentuzumab Ozogamicin and Midostaurin Combination With Standard Cytarabine and Danunorubi Midostaurin as a Novel Approach to Treating Patients With Newly Diagnosed FLT-3 Mutated Acute Myeloid Leukemia

Phase 1 Completed

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT06313437 2025-03-27

Revumenib in Combination With 7+3 + Midostaurin in AML

Phase 1 Recruiting

Other hematologic neoplasm

Leukemia, Leukemia, Myeloid, Acute

NCT00819546 2025-02-27

RAD001 in Combination With PKC412 in Patients With Relapsed, Refractory or Poor Prognosis AML or MDS

Phase 1 Active not recruiting

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT04075747 2023-10-16

V-FAST

Phase 1 Completed

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT04496999 2022-10-06

HDMM

Phase 1 Terminated

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT00093600 2020-12-19

PKC412, Daunorubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Phase 1 Completed

Other hematologic neoplasm

Congenital Abnormalities, Leukemia, Myeloid, Acute

NCT02078609 2020-12-17

A Safety and Efficacy Study of LGH447 in Patients With Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)

Phase 1 Completed

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT01282502 2018-12-12

Midostaurin (PKC412) for Locally Advanced Rectal Cancer

Phase 1 Completed

Gastrointestinal

Rectal Neoplasms

NCT01161550 2013-07-23

CLAG ATRA AML

Phase 1 Completed

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT01130662 2013-03-26

Combination of Decitabine and Midostaurin in Patients Older Than 60 With Newly Diagnosed or Relapsed Refractory Acute Myeloid Leukemia

Phase 1 Completed

Other hematologic neoplasm

Leukemia, Myeloid, Acute