NCT03280030 2025-03-20A Study of Midostaurin Efficacy and Safety in Newly Diagnosed Patients With FLT3-mutated AMLNovartisPhase 2 Completed67 enrolled 21 charts
NCT03379727 2024-02-29Study to Assess the Safety and Efficacy of Midostaurin (PKC412) in Combination With Standard Chemotherapy During Induction and Consolidation Followed by 12 Months of Maintenance Monotherapy in Patients With Newly-diagnosed FMS-like Tyrosine 3 (FLT3) Kinase Receptor-mutated Acute Myeloid Leukemia.NovartisPhase 3 Completed301 enrolled 9 charts
NCT03512197 2023-08-21A Global Study of the Efficacy and Safety of Midostaurin + Chemotherapy in Newly Diagnosed Patients With FLT3 Mutation Negative (FLT3-MN) Acute Myeloid Leukemia (AML)NovartisPhase 3 Completed511 enrolled 26 charts
NCT00093600 2020-12-19PKC412, Daunorubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid LeukemiaNovartisPhase 1 Completed69 enrolled
NCT02078609 2020-12-17A Safety and Efficacy Study of LGH447 in Patients With Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)NovartisPhase 1 Completed70 enrolled
NCT00782067 2018-11-15Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell LeukemiaNovartisPhase 2 Completed116 enrolled 16 charts