Clinical Trials Browser

Interventional × necitumumab × Clear all

NCT02496663 2026-03-18

Osimertinib and Necitumumab in Treating Patients With EGFR-Mutant Stage IV or Recurrent Non-small Cell Lung Cancer Who Have Progressed on a Previous EGFR Tyrosine Kinase Inhibitor

Phase 1 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04285671 2026-03-10

Necitumumab and Trastuzumab in Combination With Osimertinib for the Treatment of Refractory Epidermal Growth Factor Receptor (EGFR)-Mutated Stage IV Non-small Cell Lung Cancer

Phase 1/2 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00981058 2025-06-18

SQUIRE

Phase 3 Completed

1,093 enrolled 24 charts

Carcinoma, Non-Small-Cell Lung

NCT03944772 2025-01-30

ORCHARD

Phase 2 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT02789345 2024-02-05

A Study of Ramucirumab (LY3009806) or Necitumumab (LY3012211) Plus Osimertinib in Participants With Lung Cancer

Phase 1 Completed

29 enrolled 16 charts

Carcinoma, Non-Small-Cell Lung

NCT03054038 2022-04-14

Afatinib and Necitumumab in Patients With EGFR Mutation Positive Advanced or Metastatic Non-small Cell Lung Cancer

Phase 1 Terminated

Carcinoma, Non-Small-Cell Lung

NCT00982111 2022-01-11

INSPIRE

Phase 3 Completed

633 enrolled 25 charts

Carcinoma, Non-Small-Cell Lung

NCT03360734 2021-07-12

GATTO

Phase 1 Completed

Other solid neoplasm

Solid Tumor, Adult

NCT02443337 2020-12-09

A Study of LY3023414 and Necitumumab in Squamous Lung Cancer

Phase 2 Terminated

31 enrolled 14 charts

Non-small Cell Lung Cancer Metastatic

NCT02392507 2020-11-19

A Study of Nab-Paclitaxel and Carboplatin Plus Necitumumab (LY3012211) in Participants With Stage IV Squamous NSCLC

Phase 2 Completed

54 enrolled 16 charts

Carcinoma, Carcinoma, Non-Small-Cell Lung

NCT01763788 2019-10-25

A Study of Necitumumab in the First-Line Treatment of Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC)

Phase 1/2 Completed

192 enrolled 24 charts

Squamous Non-small Cell Lung Cancer

NCT01606748 2019-09-30

A Drug-Interaction Study of Necitumumab (IMC-11F8) in Combination With Gemcitabine-Cisplatin

Phase 2 Completed

35 enrolled 23 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT01769391 2019-09-20

A Study of Necitumumab and Chemotherapy in Participants With Stage IV Squamous Non-Small Cell Lung Cancer

Phase 2 Completed

167 enrolled 17 charts

Squamous Non Small Cell Lung Cancer

NCT01088464 2017-02-03

Study of IMC-11F8 in Participants With Advanced Solid Tumors

Phase 1 Completed

15 enrolled 22 charts

Neoplasms

NCT01624467 2016-07-25

A Study of Necitumumab Monotherapy and the QT/QTc Interval in Patient With Advanced Solid Tumors

Phase 2 Completed

75 enrolled 12 charts

Other solid neoplasm

Solid Tumors

NCT01788566 2016-06-27

A Study of Gemcitabine-Cisplatin Chemotherapy Plus Necitumumab in the First-Line Treatment of Participants With Squamous Lung Cancer

Phase 2 Completed

61 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung

NCT00835185 2016-01-29

Study of IMC-11F8 in Participants With Colorectal Cancer

Phase 2 Completed

44 enrolled 20 charts

Gastrointestinal

Colorectal Neoplasms