Clinical Trials Browser

NCT07178912 2026-03-09

Phase II Study of the Combination of Subcutaneous Blinatumomab and Olverembatinib in Patients With Philadelphia Chromosome (ph)-Positive and/or BCR::ABL1 Positive Acute Lymphoblastic Leukemia (ALL)

Phase 2 Not yet recruiting

60 enrolled

LymphoidOther hematologic neoplasm

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07454226 2026-03-06

ABL/JAK Inhibitors With Chemotherapy and Venetoclax for Ph-like ALL

Phase NA Not yet recruiting

30 enrolled

LymphoidOther hematologic neoplasm

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06481228 2026-03-02

Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL

Phase NA Recruiting

82 enrolled

LymphoidOther hematologic neoplasm

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06817720 2026-01-14

Phase II Study Assessing the Efficacy and Toxicity of Olverembatinib Monotherapy in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase

Phase 2 Recruiting

50 enrolled

MyeloidOther hematologic neoplasm

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT04501120 2025-09-26

Study of Lisaftoclax (APG-2575) Single Agent and Combination With Therapy in Patients Relapsed/Refractory AML

Phase 1/2 Recruiting

458 enrolled

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT07152041 2025-09-03

CAMS-Ph+ B-ALL

Phase 3 Recruiting

150 enrolled

LymphoidOther hematologic neoplasm

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06423911 2025-06-03

POLARIS-2

Phase 3 Recruiting

285 enrolled

MyeloidOther hematologic neoplasm

Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase

NCT04126681 2025-03-03

A Pivotal Study of HQP1351 in Patients With Chronic Myeloid Leukemia in Chronic Phase

Phase 2 Completed

144 enrolled

MyeloidOther hematologic neoplasm

Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase

NCT03594422 2025-02-27

A Study of HQP1351 in Patients With GIST or Other Solid Tumors

Phase 1 Recruiting

100 enrolled

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT06754267 2024-12-31

Venetoclax Combined With Olverembatinib and Predinisone in Treating Ph+ B-ALL

Phase 2 Recruiting

36 enrolled

LymphoidOther hematologic neoplasm

Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06640361 2024-12-27

A Study of Olverembatinib in SDH-deficient GIST.

Phase 3 Recruiting

40 enrolled

Sarcoma

GIST

NCT03883087 2023-04-03

A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Chronic Phase With T315I Mutation

Phase 2 Unknown

41 enrolled

Other hematologic neoplasm

Leukemia, Myeloid, Chronic-Phase

NCT03883100 2023-04-03

A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Accelerated Phase With T315I Mutation

Phase 2 Unknown

23 enrolled

Other hematologic neoplasm

Leukemia, Myeloid, Accelerated Phase

NCT05495035 2023-03-02

Study for Safety and Efficacy of Olverembatinib Combined With APG-2575 in Children With Relapsed/Refractory Ph + ALL

Phase 1 Unknown

22 enrolled

LymphoidOther hematologic neoplasm

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05521204 2022-08-30

Olverembatinib for FGFR1-rearranged Neoplasms

Phase 2 Recruiting

20 enrolled

Myeloid

Myeloproliferative Disorders

NCT05311943 2022-07-29

Treatment With Olverembatinib in CML-CP Patients Who Failed to at Least Two Previously Administered Second-generation TKIs.

Phase 3 Unknown

40 enrolled

Other hematologic neoplasm

Leukemia, Myeloid, Chronic-Phase

NCT03882281 2020-01-22

CML

Phase 1 Completed

12 enrolled

Other hematologic neoplasm

Leukemia, Myeloid, Chronic-Phase