NCT04521361 2025-09-19A Study to Assess How Radium-223 Distributes in the Body of Patients With Prostate Cancer Which Spread to the BonesBayerPhase 1 Completed46 enrolled
NCT03996473 2024-10-10Study to Test the Safety and How Radium-223 Dichloride an Alpha Particle-emitting Radioactive Agent Works in Combination With Pembrolizumab an Immune Checkpoint Inhibitor in Patients With Stage IV Non-small Cell Lung Cancer With Bone MetastasesBayerPhase 1 Terminated8 enrolled 11 charts
NCT02258451 2023-11-24Study of Radium-223 Dichloride in Combination With Exemestane and Everolimus Versus Placebo in Combination With Exemestane and Everolimus in Subjects With Bone Predominant HER2 Negative Hormone Receptor Positive Metastatic Breast CancerBayerPhase 2 Completed283 enrolled 22 charts
NCT00337155 2023-11-02BAY88-8223, Dose Finding Study in Patients With HRPCBayerPhase 2 Completed122 enrolled
NCT00667199 2023-04-19BAY88-8223, Does Response Study in HRPC PatientsBayerPhase 2 Completed100 enrolled
NCT02258464 2020-08-10Study of Radium-223 Dichloride Versus Placebo and Hormonal Treatment as Background Therapy in Subjects With Bone Predominant HER2 (Human Epidermal Growth Factor Receptor 2) Negative Hormone Receptor Positive Metastatic Breast CancerBayerPhase 2 Terminated99 enrolled 18 charts
NCT02928029 2020-02-26Study Testing Radium-223 Dichloride in Relapsed Multiple MyelomaBayerPhase 1/2 Terminated7 enrolled 9 charts
NCT02814669 2019-09-24Safety and Tolerability of Atezolizumab (ATZ) in Combination With Radium-223 Dichloride (R-223-D) in Metastatic Castrate-Resistant Prostate Cancer (CRPC) Progressed Following Treatment With an Androgen Pathway InhibitorHoffmann-La RochePhase 1 Completed45 enrolled
NCT02034552 2019-07-23A Randomized Phase IIa Efficacy and Safety Study of Radium-223 Dichloride With Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (CRPC)BayerPhase 2 Completed68 enrolled 17 charts
NCT02023697 2019-07-12Standard Dose Versus High Dose and Versus Extended Standard Dose Radium-223 Dichloride in Castration-resistant Prostate Cancer Metastatic to the BoneBayerPhase 2 Completed391 enrolled 53 charts
NCT01810770 2018-09-19Radium-223 Dichloride Asian Population Study in the Treatment of CRPC Patients With Bone MetastasisBayerPhase 3 Completed243 enrolled
NCT01929655 2018-04-24Japanese BAY88-8223 Monotherapy Phase II StudyBayerPhase 2 Completed49 enrolled
NCT01934790 2018-03-26Re-treatment Safety of Radium-223 Dichloride in Castration-resistant Prostate Cancer With Bone MetastasesBayerPhase 1/2 Completed45 enrolled 23 charts
NCT01798108 2017-05-19Dose Escalation Study of Radium-223 Dichloride in Patients With Advanced Skeletal MetastasesBayerPhase 1 Completed31 enrolled
NCT02442063 2016-11-30Phase Ib Study of Radium Ra 223 Dichloride in Combination With Paclitaxel in Cancer Subjects With Bone LesionsBayerPhase 1 Completed15 enrolled
NCT01565746 2016-10-17Safety, Biodistribution, Radiation Dosimetry and Pharmacokinetics Study of BAY88-8223 in Japanese PatientsBayerPhase 1 Completed19 enrolled
NCT02605356 2016-10-07Phase 1b/2 Study Testing Radium-223 Dichloride/Bortezomib/Dexamethasone Combination in Relapsed Multiple MyelomaBayerPhase 1/2 Withdrawn
NCT00459654 2014-06-25A Placebo-controlled Phase II Study of Bone-targeted Radium-223 in Symptomatic Hormone-refractory Prostate CancerBayerPhase 2 Completed64 enrolled
NCT00748046 2014-06-25Alpharadinâ„¢ (Radium-223 Chloride) Safety and Dosimetry With HRPC That Has Metastasized to the SkeletonBayerPhase 1 Completed10 enrolled
NCT01070485 2014-06-25BAY88-8223, Alpharadin, Breast Cancer Patients With Bone Dominant DiseaseBayerPhase 2 Completed23 enrolled