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NCT03878199 2025-09-15

Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms

Phase 1/2 Completed

Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Primary Myelofibrosis

NCT04669210 2025-07-04

PTCyRuxo

Phase 2 Completed

LymphoidOther hematologic neoplasm

Graft vs Host Disease, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01375140 2025-06-08

Ruxolitinib and Lenalidomide for Patients With Myelofibrosis

Phase 2 Completed

31 enrolled 8 charts

Polycythemia Vera, Primary Myelofibrosis

NCT02257138 2025-06-08

Ruxolitinib Phosphate and Decitabine in Treating Patients With Relapsed or Refractory or Post Myeloproliferative Acute Myeloid Leukemia

Phase 1/2 Completed

30 enrolled 14 charts

MyeloidOther hematologic neoplasm

Leukemia, Myeloid, Acute, Myelodysplastic-Myeloproliferative Diseases

NCT05440942 2025-06-05

Combined MEK, STAT3 and PD-1 Inhibition in Metastatic Pancreatic Ductal Adenocarcinoma

Phase 1 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT02713386 2025-05-25

Ruxolitinib Phosphate, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Phase 1/2 Completed

147 enrolled 18 charts

Fallopian Tube Neoplasms

NCT01895842 2025-02-28

Ruxolitinib for Patients With Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)

Phase 1 Completed

MyeloidOther hematologic neoplasm

Leukemia, Myelodysplastic Syndromes

NCT04281498 2025-02-04

Combined Ruxolitinib and Enasidenib in Patients With Accelerated/Blast-phase Myeloproliferative Neoplasm or Chronic-phase Myelofibrosis With an IDH2 Mutation

Phase 2 Completed

6 enrolled 11 charts

Primary Myelofibrosis

NCT03773107 2025-01-13

LCI-HEM-MYE-CRD-004 (MMRC-073 CARJAK): Study of CRD for Carfilzomib-Refractory Multiple Myeloma

Phase 1/2 Completed

12 enrolled 19 charts

Multiple Myeloma, Neoplasms, Plasma Cell

NCT02493530 2024-06-27

TGR-1202 + Ruxolitinib PMF PPV-MF PET-MF MDS/MPN Polycythemia Vera Resistant to Hydroxyurea

Phase 1 Completed

Polycythemia Vera, Primary Myelofibrosis

NCT01594216 2024-06-12

Ruxolitinib in Estrogen Receptor Positive Breast Cancer

Phase 2 Completed

25 enrolled 8 charts

Estrogen-receptor Positive Invasive Metastatic Breast Cancer

NCT05663827 2024-03-05

Ruxolitinib as add-on Therapy in Steroid-refractory Graft-vs-host Disease

Phase 3 Completed

LymphoidOther hematologic neoplasm

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03012230 2024-01-31

Pembrolizumab and Ruxolitinib Phosphate in Treating Patients With Metastatic Stage IV Triple Negative Breast Cancer

Phase 1 Completed

Triple Negative Breast Neoplasms

NCT04055844 2023-11-07

Multi-Ctr PII Cmb.Modality Tx Ruxolitinib, Decitabine, and DLI for Post HSCT in AML/MDS

Phase 2 Completed

14 enrolled 20 charts

MyeloidOther hematologic neoplasm

Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT01712308 2023-10-10

Sotatercept in Treating Patients With Myeloproliferative Neoplasm-Associated Myelofibrosis or Anemia

Phase 2 Completed

56 enrolled 9 charts

Classical hematologyMyeloid

Anemia, Myelodysplastic-Myeloproliferative Diseases, Primary Myelofibrosis

NCT02066532 2023-08-24

Ruxolitinib in Combination With Trastuzumab in Metastatic HER2 Positive Breast Cancer

Phase 1/2 Completed

32 enrolled 13 charts

Breast Neoplasms

NCT01776723 2022-09-22

A Sequential Two-Stage Dose Escalation Study to Evaluate the Safety and Efficacy of Ruxolitinib

Phase 1/2 Completed

50 enrolled 17 charts

Other hematologic neoplasm

Leukemia, Leukemia, Myelomonocytic, Chronic

NCT02613598 2021-12-20

Dose Escalation Study to Determine the Maximum Tolerated Dose of the Combination of Ruxolitinib and Bortezomib in Patients With Relapsed or Refractory Lymphoma

Phase 1 Completed

Hodgkin Disease, Lymphoma, Non-Hodgkin

NCT02041429 2021-04-21

Ruxolitinib W/ Preop Chemo For Triple Negative Inflammatory Brca

Phase 1/2 Completed

20 enrolled 23 charts

Breast Neoplasms

NCT01702064 2021-01-05

Ruxolitinib in Combination With Nilotinib in Chronic Myeloid Leukemia (CML) Patients

Phase 1 Completed

MyeloidOther hematologic neoplasm

Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase

NCT02092324 2020-11-16

Ruxolitinib Phosphate in Treating Patients With Chronic Neutrophilic Leukemia or Atypical Chronic Myeloid Leukemia

Phase 2 Completed

51 enrolled 25 charts

Other hematologic neoplasm

Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

NCT01914484 2020-11-02

Phase I/II Study of Nilotinib/Ruxolitinb Therapy for TKI Resistant Ph-Leukemia

Phase 1/2 Completed

LymphoidMyeloidOther hematologic neoplasm

Blast Crisis, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02779283 2020-05-26

Personalized Kinase Inhibitor Therapy Combined With Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia

Phase 1 Completed

LymphoidOther hematologic neoplasm

Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02267278 2019-06-12

Ruxolitinib and Pracinostat Combination Therapy for Patients With Myelofibrosis (MF)

Phase 2 Completed

25 enrolled 8 charts

Polycythemia Vera, Primary Myelofibrosis

NCT02142036 2019-03-13

MetAction

Phase 2 Completed

Neoplasm Metastasis

NCT02076191 2019-02-28

Study of Combination Ruxolitinib and Decitabine Treatment for Accelerated Phase MPN or Post-MPN AML

Phase 1/2 Completed

Myeloproliferative Disorders

NCT01965119 2018-11-01

JAK2

Phase 2 Completed

Hodgkin Disease, Recurrence

NCT01877005 2018-08-22

HIJAK

Phase 2 Completed

Hodgkin Disease

NCT02015208 2016-09-26

Ruxolitinib in the Treatment of Chronic Lymphocytic Leukemia

Phase 1/2 Completed

LymphoidOther hematologic neoplasm

Leukemia, Lymphocytic, Chronic, B-Cell