NCT01769768 2020-12-19Phase I Study to Evaluate the Effect of LDE225 on the Pharmacokinetics of Bupropion and Warfarin in PatientsNovartisPhase 1 Completed114 enrolled
NCT01456676 2020-12-09Nilotinib and LDE225 in the Treatment of Chronic or Accelerated Phase Myeloid Leukemia in Patients Who Developed Resistance to Prior TherapyNovartisPhase 1 Completed11 enrolled
NCT01787552 2020-04-15A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MFNovartisPhase 1/2 Completed50 enrolled 23 charts
NCT01708174 2017-08-11A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB)NovartisPhase 2 Completed22 enrolled 12 charts
NCT01826214 2016-08-30Study of Efficacy and Safety of LDE225 in Adult Patients With Relapsed/Refractory Acute LeukemiaNovartisPhase 2 Completed70 enrolled 12 charts
NCT01350115 2015-10-19Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)NovartisPhase 2 Completed10 enrolled 9 charts