NCT04821622 2026-03-11Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPCPfizerPhase 3 Active not recruiting599 enrolled
NCT04991480 2026-01-27A Study of ART4215 for the Treatment of Advanced or Metastatic Solid TumorsArtios Pharma LtdPhase 1 Completed93 enrolled
NCT05059522 2025-06-25Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are ClosingPfizerPhase 3 Active not recruiting68 enrolled
NCT04672460 2024-09-25A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid TumorsPfizerPhase 1 Completed73 enrolled 18 charts
NCT03343054 2024-08-22A Phase 1 Study Of Talazoparib, PARP Inhibitor, In Japanese Patients With Advanced Solid TumorsPfizerPhase 1 Completed28 enrolled 43 charts
NCT03148795 2024-04-05A Study of Talazoparib in Men With DNA Repair Defects and Metastatic Castration-Resistant Prostate CancerPfizerPhase 2 Completed128 enrolled 25 charts
NCT03330405 2023-10-13Javelin Parp Medley: Avelumab Plus Talazoparib In Locally Advanced Or Metastatic Solid TumorsPfizerPhase 1/2 Terminated223 enrolled 50 charts
NCT03565991 2023-09-25Javelin BRCA/ATM: Avelumab Plus Talazoparib in Patients With BRCA or ATM Mutant Solid TumorsPfizerPhase 2 Terminated202 enrolled 31 charts
NCT02921919 2022-08-24Open-Label Extension and Safety Study of TalazoparibPfizerPhase 2 Completed120 enrolled 16 charts
NCT03875313 2022-02-17Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid TumorsCalithera Biosciences, IncPhase 1/2 Terminated33 enrolled 14 charts
NCT03499353 2021-11-09Talazoparib For Neoadjuvant Treatment Of Germline BRCA1/2 Mutation Patients With Early Human Epidermal Growth Factor Receptor 2 Negative Breast CancerPfizerPhase 2 Terminated61 enrolled 63 charts
NCT04052204 2021-10-14Avelumab With Bempegaldesleukin With or Without Talazoparib or Enzalutamide in Advanced or Metastatic Solid TumorsPfizerPhase 1/2 Terminated3 enrolled 12 charts
NCT03077607 2021-06-30A Study to Evaluate the Effect of Itraconazole and Rifampin on the Pharmacokinetics of Talazoparib in Patients With Advanced Solid TumorsPfizerPhase 1 Completed36 enrolled 28 charts
NCT02997163 2021-01-05An Open-Label Pharmacokinetics and Safety Study of TalazoparibPfizerPhase 1 Completed34 enrolled 39 charts
NCT03042910 2019-12-17A Study to Assess the Effects of Talazoparib on Cardiac Repolarization in Patients With Advanced Solid TumorsPfizerPhase 1 Completed38 enrolled 24 charts
NCT01286987 2019-01-10Study of Talazoparib, a PARP Inhibitor, in Patients With Advanced or Recurrent Solid TumorsPfizerPhase 1 Completed113 enrolled 39 charts
NCT03070548 2018-12-17A Study of Talazoparib in Patients With Advanced Solid TumorsPfizerPhase 1 Completed6 enrolled 34 charts
NCT02836028 2018-09-18A Study Evaluating Talazoparib in Relapsed Ovarian, Fallopian Tube, and Peritoneal CancerPfizerPhase 2 Withdrawn
NCT01399840 2017-09-15Study of BMN 673, a PARP Inhibitor, in Patients With Advanced Hematological MalignanciesPfizerPhase 1 Completed33 enrolled