NCT00807859 2022-11-08Safety Study of AMG 386 to Treat HER2-positive Locally Recurrent or Metastatic Breast CancerAmgenPhase 1 Completed65 enrolled
NCT01331941 2017-11-06A Pharmacokinetic Study of AMG 386 in Cancer Subjects With Normal and Impaired Renal FunctionAmgenPhase 1 Completed35 enrolled
NCT00861419 2017-02-08To Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 386 When Used in Combination With AMG 706, Bevacizumab, Sorafenib, or Sunitinib.AmgenPhase 1 Completed88 enrolled
NCT01253681 2015-10-14Study of AMG 386 in Combination With Paclitaxel and Carboplatin in Subjects With Ovarian CancerAmgenPhase 1 Completed27 enrolled
NCT00770536 2015-09-29AMG386 Comb w. Either Pegylated Liposomal Doxorubicin or Topotecan Subjects w. Advanced Recurrent Epithelial Ovarian CRAmgenPhase 1 Completed103 enrolled
NCT02525536 2015-09-22A Phase 1 Study Evaluating the Safety, Tolerability and Pharmacokinetics of Trebananib (AMG 386 ) in Adult Japanese Participants With Advanced Solid TumorsTakedaPhase 1 Completed18 enrolled 38 charts
NCT01992341 2014-09-23AMG 386 Drug-Drug Interaction Study With PaclitaxelAmgenPhase 1 Completed35 enrolled
NCT00102830 2010-08-20Study Evaluating AMG 386 in Adult Patients With Advanced Solid TumorsAmgenPhase 1 Completed