Clinical Trials Browser

Biliary Tract Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Head and Neck Neoplasms, Neoplasm Metastasis, Stomach Neoplasms, Colorectal Neoplasms, Sarcoma, Alveolar Soft Part

NCT01867866 2024-09-05

Study Comparing the Pharmacokinetics of FTD as a Component of TAS-102 With FTD Alone

Phase 1 Completed

44 enrolled

Other solid neoplasm

Advanced Solid Tumors

NCT01867879 2024-09-05

Study to Evaluate the Cardiac Safety of TAS-102 in Patients With Advanced Solid Tumors

Phase 1 Completed

44 enrolled

BreastOther solid neoplasm

Advanced Solid Tumors (Excluding Breast Cancer)

NCT01874522 2024-09-05

Study Comparing the Bioavailability of TAS-102 Tablets to an Oral Solution Containing Equivalent Amounts of FTD and TPI

Phase 1 Completed

46 enrolled

BreastOther solid neoplasm

Advanced Solid Tumors (Excluding Breast Cancer)

NCT01916447 2024-09-05

A Phase I Study of TAS-102 in Patients With Advanced Gastrointestinal Tumors.

Phase 1 Completed

65 enrolled

Gastrointestinal

Advanced Gastrointestinal Tumors

NCT02031055 2024-09-05

Study of the Mass Balance of Oral FTD and TPI as Components of TAS-102 in Patients With Advanced Solid Tumors

Phase 1 Completed

8 enrolled

Other solid neoplasm

Advanced Solid Tumors

NCT02301104 2024-09-05

A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Hepatic Impairment

Phase 1 Completed

24 enrolled

Gastrointestinal

Liver Diseases, Liver Neoplasms

NCT02301117 2024-09-05

A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment

Phase 1 Completed

43 enrolled

Genitourinary

Carcinoma, Renal Cell, Kidney Diseases, Kidney Neoplasms, Urologic Diseases, Renal Insufficiency

NCT04073615 2024-05-02

A Study of Rivoceranib and Trifluridine/Tipiracil for Metastatic Colorectal Cancer (mCRC)

Phase 1 Terminated

29 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT03810742 2023-11-18

Nanoliposomal Irinotecan (Nal-IRI, ONIVYDE®) in Combination With TAS-102 (LONSURF®) in Refractory Solid Tumors

Phase 1 Completed

44 enrolled

Other solid neoplasm

Refractory Solid Tumors

NCT03616574 2022-09-21

First-in-human Study of CA102N Monotherapy and CA102N Combined With Trifluridine/Tipiracil (LONSURF) in Subjects With Advanced Solid Tumors

Phase 1 Completed

37 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT03974594 2022-04-19

Bioequivalence Study of Trifluridine and Tipiracil Tablets in Colorectal Cancer Patients

Phase 1 Completed

64 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT03031691 2020-08-11

A Study of Brontictuzumab With Chemotherapy for Subjects With Previously Treated Metastatic Colorectal Cancer

Phase 1 Completed

7 enrolled

Gastrointestinal

Colorectal Neoplasms