NCT01240642 2020-12-09An Open-label, Dose Escalation Multi-center Study in Patients With Advanced Cancer to Determine the Infusion Rate Effect of ASA 404 With Paclitaxel Plus Carboplatin Regimen or Docetaxel on the Pharmacokietics of Free and Total ASA404NovartisPhase 1 Terminated27 enrolled
NCT01278758 2020-12-09A Dose-escalation Pharmacokinetic Study of Intravenous ASA404 in Adult Advanced Cancer Patients With Impaired Renal Function and Patients With Normal Renal FunctionNovartisPhase 1 Terminated7 enrolled
NCT01278849 2020-12-09An Open-label, Dose Escalation Study to Assess the Pharmacokinetics of of ASA404 in Adult Cancer Patients With Impaired Hepatic FunctionNovartisPhase 1 Terminated5 enrolled
NCT01299701 2017-02-14A Single Center Study to Characterize the Absorption, Distribution, Metabolism and Excretion (ADME) of ASA404 After a Single Infusion in Patients With Solid TumorsNovartisPhase 1 Terminated7 enrolled
NCT01290380 2011-09-02A Study to Evaluate the Effects of ASA404 Alone or in Combination With Taxane-based Chemotherapies on the Pharmacokinetics of Drugs in Patients With Advanced Solid Tumor MalignanciesNovartisPhase 1 Terminated54 enrolled
NCT01299415 2011-09-02Safety and Pharmacokinetics of ASA404 When Given Together With Fluvoxamine, a Selective Serotonin Receptor Reuptake Inhibitor and CYP1A2 InhibitorNovartisPhase 1 Terminated17 enrolled