Clinical Trials Browser

Phase 3 × Interventional × vandetanib × Clear all

NCT00410761 2025-09-24

An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer

Phase 3 Completed

331 enrolled 15 charts

EndocrineHead & Neck

Familial medullary thyroid carcinoma, Thyroid Neoplasms, Carcinoma, Medullary

NCT01298323 2025-04-24

Study to Determine if Contacting Patients With MTC More Frequently Results in Earlier Detection and Treatment of Signs and Symptoms of AEs and Thus a Decrease in the Percentage of Time Patients Experience AEs During First 12 Months on Vandetanib Treatment

Phase 3 Completed

205 enrolled 9 charts

Neoplasm Metastasis, Carcinoma, Medullary

NCT04211337 2025-04-20

LIBRETTO-531

Phase 3 Active not recruiting

291 enrolled 16 charts 1 FDA

Carcinoma, Medullary

NCT04760288 2024-01-05

AcceleRET-MTC

Phase 3 Withdrawn

Carcinoma, Medullary

NCT00364351 2018-01-25

Efficacy Trial Comparing ZD6474 With Erlotinib in NSCLC After Failure of at Least One Prior Chemotherapy

Phase 3 Completed

1,574 enrolled 13 charts

Carcinoma, Non-Small-Cell Lung

NCT00312377 2016-09-30

ZODIAC

Phase 3 Completed

1,690 enrolled 15 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00404924 2016-09-30

ZD6474 (ZACTIMA™) Phase III Study in EGFR Failures

Phase 3 Completed

1,140 enrolled 12 charts

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Carcinoma, Large Cell