Durvalumab and Vicineum in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Guerin (BCG)
Phase 1 Completed
15 enrolled 21 charts
Administration of Anti-CD19-chimeric-antigen-receptor-transduced T Cells From the Original Transplant Donor to Patients With Recurrent or Persistent B-cell Malignancies After Allogeneic Stem Cell Transplantation
Phase 1 Completed
85 enrolled
Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors
Phase 1 Completed
27 enrolled
Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy
Phase 1 Completed
30 enrolled 16 charts
FdCyd and THU for Advanced Solid Tumors
Phase 1 Completed
59 enrolled
Romidepsin, CC-486 (5-azacitidine), Dexamethasone, and Lenalidomide (RAdR) for Relapsed/Refractory T-cell Malignancies
Phase 1 Completed
26 enrolled 24 charts
Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma
Phase 1 Completed
12 enrolled 12 charts
Dasatinib in Combination With Bevacizumab to Treat Advanced Solid Tumors
Phase 1 Completed
50 enrolled
Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors
Phase 1 Completed
18 enrolled
Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma
Phase 1 Completed
17 enrolled
Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1
Phase 1 Completed
10 enrolled
Endoxifen in Adults With Hormone Receptor Positive Solid Tumors
Phase 1 Completed
40 enrolled
Lenalidomide and Blinatumomab for the Treatment of Relapsed Non-Hodgkin Lymphoma
Phase 1 Completed
35 enrolled
Veliparib and Temozolomide in Treating Patients With Acute Leukemia
Phase 1 Completed
66 enrolled
Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer
Phase 1 Completed
40 enrolled 17 charts
Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
Phase 1 Completed
83 enrolled 21 charts
Prostate SBRT for Locally Recurrent Prostate Cancer After Prior Radiotherapy
Phase 1 Completed
17 enrolled 20 charts
Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread
Phase 1 Completed
3 enrolled 12 charts
Testing the Safety of Adding Either Monalizumab (IPH2201) or Oleclumab (MEDI9447) to Durvalumab (MEDI4736) Plus Standard Radiation Therapy for Locally Advanced Non-small Cell Lung Cancer (NSCLC), ARCHON-1 Trial
Phase 1 Completed
26 enrolled 17 charts
A Comparison of Methods for Assisting Needle Angle Selection During Image-guided Tissue Biopsy
Phase 1 Completed
17 enrolled
A Phase I Study of Indenoisoquinolines LMP400 and LMP776 in Adults With Relapsed Solid Tumors and Lymphomas
Phase 1 Completed
55 enrolled
Ixazomib and Pevonedistat in Treating Patients With Multiple Myeloma That Has Come Back or Does Not Respond to Treatment
Phase 1 Completed
8 enrolled 11 charts
CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies
Phase 1 Completed
54 enrolled 24 charts
Veliparib and Irinotecan Hydrochloride in Treating Patients With Cancer That Is Metastatic or Cannot Be Removed by Surgery
Phase 1 Completed
73 enrolled
Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome
Phase 1 Completed
12 enrolled 16 charts
Testing Nivolumab in Combination With Decitabine and Venetoclax in Patients With Newly Diagnosed TP53 Gene Mutated Acute Myeloid Leukemia
Phase 1 Completed
1 enrolled 8 charts
Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction
Phase 1 Completed
46 enrolled
Onalespib in Treating Patients With Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck Receiving Radiation Therapy and Cisplatin
Phase 1 Completed
2 enrolled
The Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration In Men With Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females
Phase 1 Completed
12 enrolled 11 charts
Onalespib and CDKI AT7519 in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
Phase 1 Completed
29 enrolled
Liposomal Irinotecan and Veliparib in Treating Patients With Solid Tumors
Phase 1 Completed
18 enrolled
Venetoclax With Obinutuzumab and Magrolimab (VENOM) in Relapsed and Refractory Indolent B-cell Malignancies
Phase 1 Completed
11 enrolled 16 charts
Adavosertib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma
Phase 1 Completed
74 enrolled
Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors
Phase 1 Completed
29 enrolled
Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma
Phase 1 Completed
29 enrolled
Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer
Phase 1 Completed
58 enrolled 17 charts
Wild-Type Reovirus in Combination With Carfilzomib and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
Phase 1 Completed
12 enrolled
A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors
Phase 1 Completed
15 enrolled
Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer
Phase 1 Completed
Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors
Phase 1 Completed
Vaccine Therapy in Treating Patients With Metastatic Cancer
Phase 1 Completed
BMS-247550 in Treating Patients With Cancers That Have Not Responded to Previous Therapy
Phase 1 Completed
Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas
Phase 1 Completed
46 enrolled 20 charts
Cabozantinib S-Malate in Treating Younger Patients With Recurrent or Refractory Solid Tumors
Phase 1 Completed
41 enrolled 20 charts
Stereotactic Radiosurgery in Treating Patients With Brain Tumors
Phase 1 Completed
Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
Phase 1 Completed
21 enrolled 15 charts
Testing the Addition of the Anti-Cancer Drug Talazoparib to the Combination of Carboplatin and Paclitaxel for the Treatment of Advanced Cancer
Phase 1 Completed
43 enrolled
Sunitinib Malate and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Chemotherapy
Phase 1 Completed
40 enrolled
Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors
Phase 1 Completed
19 enrolled 22 charts
Ipilimumab, Cetuximab, and Intensity-Modulated Radiation Therapy in Treating Patients With Previously Untreated Stage III-IVB Head and Neck Cancer
Phase 1 Completed
19 enrolled