Clinical Trials

31 enrolled

Esophageal Neoplasms, Ornithine Carbamoyltransferase Deficiency Disease

NCT07478848 2026-03-18

Radiation, Oral Vancomycin, and CAR-T for B-Cell Lymphomas

14 enrolled

Lymphoma, Non-Hodgkin, Lymphoma, Large B-Cell, Diffuse

NCT07478679 2026-03-17

Radiation to Treat Joint Damage Caused by Cancer Immunotherapy

Arthritis, Joint Diseases

NCT04579523 2026-03-13

²¹¹At-OKT10-B10 and Fludarabine Alone or in Combination With Cyclophosphamide and Low-Dose TBI Before Donor Stem Cell Transplant for the Treatment of Newly Diagnosed, Recurrent, or Refractory High-Risk Multiple Myeloma

Plasma cell

Multiple Myeloma

NCT07133997 2026-03-13

Recombinant Erwinia Asparaginase and Venetoclax in Combination With Blinatumomab for the Treatment of Relapsed or Refractory CD19 Positive B-cell Acute Lymphoblastic Leukemia

26 enrolled

Burkitt Lymphoma

NCT07454031 2026-03-13

Intraperitoneal PX in Combination With Nab-Paclitaxel in Patients With Peritoneal Metastatic Mucinous Adenocarcinoma

22 enrolled

Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

NCT07469982 2026-03-13

A Phase I Study of SY-9453 in Patients With Advanced Solid Tumors

122 enrolled

Other solid neoplasm

Advanced or Metastatic Solid Tumors With Homozygous MTAP Deletion

NCT06502171 2026-03-12

NF113

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT07140315 2026-03-12

DK222 Study at Hopkins

6 enrolled

GenitourinaryThoracic

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT07436988 2026-03-12

ReLIVE

Carcinoma, Hepatocellular, Liver Neoplasms

NCT07237594 2026-03-11

REPLAY

4 enrolled

Dermatologic

Melanoma

NCT07444632 2026-03-11

Phase1 Basket Trial Of CAR.70-Engineered IL15-Transduced With TGFBR2 Knock Out Cord Blood-Derived NK Cells For Relapsed/Refractory Lymphoid Malignancies

60 enrolled

Hodgkin Disease

NCT07464951 2026-03-11

CART123

Leukemia, Leukemia, Myeloid, Acute

NCT07459595 2026-03-10

Metformin Versus Myo-inositol in the Management of Polycystic Ovarian Disease: A Comparative Study

60 enrolled

Polycystic Ovary Syndrome

NCT07460765 2026-03-10

Safety and Feasibility of Nivolumab-IRDye800CW in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC)

40 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Mouth Neoplasms, Neoplasms, Squamous Cell

NCT07461727 2026-03-10

An Open-Label, Single-Arm, Dose-Escalation Phase I Study Evaluating the Safety, Tolerability, and Preliminary Efficacy of EDB-102 in Patients With EGFR L858R-Mutant, Third-Generation TKI-Resistant Advanced Non-Small Cell Lung Cancer With Liver Metastases

15 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT07457307 2026-03-09

INSIGHT MRL

Glioma

NCT07453875 2026-03-06

TRIUNITE06

9 enrolled

Colorectal Neoplasms

NCT07454668 2026-03-06

Trastuzumab Deruxtecan + Stereotactic Radiosurgery (SRS) in HER2+ Breast Cancer Brain Metastases

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT07455032 2026-03-06

Neoadjuvant CADI-05 in Combination With Pembrolizumab for Surgically Resectable Locally Advanced Head and Neck Squamous Cell Carcinomas

22 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT05038098 2026-03-05

Magnetic Sentinel Lymph Node Mapping in Gastric Cancer

Gastric Adenocarcinoma

NCT07451054 2026-03-05

CD45BE-HSPC + CART-45 Cells

42 enrolled

Hodgkin Disease, Lymphoma, B-Cell, Lymphoma, T-Cell

NCT06251544 2026-03-04

TRAIL-R2 and HER2 Bi-Specific Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Metastatic Breast Cancer

27 enrolled

Breast

Breast Neoplasms, Mammary Neoplasms, Animal

NCT07220993 2026-03-04

Novel Unedited Allo Cell Therapy For High Risk T-Cell Malignancies Using CD7-Specific Car T Cells

LymphoidOther hematologic neoplasm

27 enrolled

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT07297160 2026-03-04

CALySSEY

GenitourinaryLymphoidOther hematologic neoplasmPlasma cellSarcoma

88 enrolled

Kidney Neoplasms, Lymphoma, Sarcoma, Hematologic Neoplasms, Neoplasms, Plasma Cell

NCT07439211 2026-03-03

GAVEL

48 enrolled

Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute

NCT07444606 2026-03-03

Dose Ranging, Toxicity Seeking, Phase 1 Trial of Oncolytic Adenoviral Therapy for Melanoma Intracranial and Extracranial Metastases

50 enrolled

Dermatologic

Melanoma

NCT07444619 2026-03-03

A Phase I Study of Pazopanib in Combination With Trabectedin, Ipilimumab and Nivolumab (TraPIN) in Pediatric and Young Adult Patients With Recurrent Soft Tissue Sarcomas

Sarcoma

NCT07441980 2026-03-02

A Clinical Study to Explore the Safety and Efficacy of CT1390B in Relapsed/ Refractory Acute Myeloid Leukemia

Leukemia, Myeloid, Acute

NCT07443020 2026-03-02

RIOT 4B

Other solid neoplasmThoracic

10 enrolled

Mesothelioma, Malignant, Pleural Effusion, Malignant

NCT07443137 2026-03-02

CAR-T ceLL for Eradication of Active Residual Disease in LBCL (CLEAR-1 Study)

Sarcoma

Dendritic Cell Sarcoma, Interdigitating

NCT07224776 2026-02-27

Sparsentan for the Treatment of VEGF Signaling Pathway Inhibitor-Associated Proteinuria

Neoplasms, Proteinuria

NCT07401875 2026-02-27

A Phase 1b Study of HC-7366, an Agonist of ISR With Immunotherapy in Kidney Cancer (SHARK)

35 enrolled

Genitourinary

Kidney Neoplasms

NCT07417488 2026-02-27

GUCY2C Prime-Boost Vaccination for Advanced Colorectal and Small Bowel Adenocarcinomas

Colorectal Neoplasms

NCT07438860 2026-02-27

Fluorescence-Guided Imaging of Brain Tumors: A Safety Study Using SBK2-ICG

12 enrolled

Glioma

NCT07076498 2026-02-25

Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation

Diffuse Intrinsic Pontine Glioma, Glioma

NCT07432100 2026-02-25

Clinical Study on the Safety, Efficacy and Pharmacokinetics of Universal CLL1 Chimeric Antigen Receptor T-Cell in Relapsed/Refractory Acute Myeloid Leukemia

Leukemia, Myeloid, Acute

NCT07430202 2026-02-24

A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipilimumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

27 enrolled

Fibrolamellar hepatocellular carcinoma, Carcinoma, Liver Neoplasms

NCT07177079 2026-02-23

High-dose Ascorbate (HDA) in Combination With Standard of Care Azacitidine and Venetoclax in Acute Myeloid Leukemia (AML)

Leukemia, Myeloid, Acute

NCT07428486 2026-02-23

A Phase 1 Study Of FLAG Chemotherapy In Combination With Lisaftoclax And Pelcitoclax In Patients With Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia

LymphoidOther hematologic neoplasm

24 enrolled

Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07382726 2026-02-20

Phase 1 Study Of Izalontamab Brengitecan + Adagrasib In NSCLC - The IZA-A Trial

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT07422896 2026-02-20

Bvax

25 enrolled

Glioblastoma

NCT06941480 2026-02-19

A Study of 177Lu-DTPA-SC16.56 in People With Neuroendocrine Carcinomas of the Lung and Prostate

12 enrolled

Endocrine

Carcinoma, Neuroendocrine

NCT07082270 2026-02-19

Selvigaltin With Standard of Care Treatment for the Treatment of Relapsed/Refractory Multiple Myeloma

21 enrolled

Plasma cell

Multiple Myeloma

NCT07117032 2026-02-19

Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy (SBRT) in Participants With Cancer-Related Celiac Pain

5 enrolled

Pancreatic Neoplasms, Abdominal Pain

NCT05521698 2026-02-17

Study to Determine Possible Effects of Apalutamide, Compared to Placebo, on EGFR Expression in Patients With Non-muscle Invasive Bladder Cancer

80 enrolled

Genitourinary

Non-Muscle Invasive Bladder Urothelial Carcinoma

NCT07411586 2026-02-17

Phase 1/1b Trial Of Olutasidenib And Ziftomenib For NPM1 And IDH1 Co-Mutated Acute Myeloid Leukemia

Leukemia, Myeloid, Acute

NCT07411781 2026-02-17

PIN in Combination With Sintilimab in Previously Treated pMMR/MSS CRC With Hepatic Metastases

25 enrolled

Colorectal Neoplasms

NCT07300475 2026-02-13

Cancer Immunotherapeutic (PCI) Strategy in Triple Negative Breast Cancer Patients