VB-111 in Combination With Nivolumab in People With Metastatic Colorectal Cancer (mCRC)
Phase 2 Terminated
14 enrolled 13 charts
Testing the Use of Fulvestrant and Binimetinib Targeted Treatment for NF1 Mutation in Hormone Receptor-Positive Metastatic Breast Cancer (A ComboMATCH Treatment Trial)
Phase 2 Terminated
1 enrolled
Nivolumab (Anti-PD1), Tadalafil and Oral Vancomycin in People With Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer From Colorectal or Pancreatic Cancers
Phase 2 Terminated
22 enrolled 13 charts
A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer
Phase 2 Terminated
9 enrolled 11 charts
Sacituzumab Govitecan for Relapsed Ovarian, Endometrial, and Cervical Carcinomas
Phase 2 Terminated
2 enrolled 7 charts
Treatment of Cancer-Related Bone Pain by Using Bone-Targeted Radiation-Based Therapy (Sn-117m-DTPA) in Patients With Prostate Cancer That Has Spread to Bones
Phase 2 Terminated
1 enrolled 8 charts
18F-DCFPyL PET/CT in Hepatocellular Carcinoma
Phase 2 Terminated
8 enrolled 14 charts
Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)
Phase 2 Terminated
90 enrolled 24 charts
Tocilizumab for Patients With Cancer and COVID-19 Disease
Phase 2 Terminated
1 enrolled 10 charts
Olaparib (LYNPARZA) Plus Durvalumab (IMFINZI) in EGFR-Mutated Adenocarcinomas That Transform to Small Cell Lung Cancer (SCLC) and Other Neuroendocrine Tumors
Phase 2 Terminated
4 enrolled 11 charts
Carboplatin and Paclitaxel With or Without Vorinostat in Treating Patients With Advanced Non-Small Cell Lung Cancer
Phase 2 Terminated
23 enrolled 10 charts
LMB-100 Followed by Pembrolizumab in the Treatment of Adults With Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Phase 2 Terminated
6 enrolled 14 charts
Ketoconazole With or Without Alendronate Sodium in Treating Patients With Metastatic Prostate Cancer
Phase 2 Terminated
Olaparib, Cediranib Maleate, and Standard Chemotherapy in Treating Patients With Small Cell Lung Cancer
Phase 2 Terminated
9 enrolled 4 charts
Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC).
Phase 2 Terminated
2 enrolled 9 charts
Dasatinib in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, Endometrial or Peritoneal Cancer
Phase 2 Terminated
35 enrolled 13 charts
ACTOplus Met XR in Treating Patients With Stage I-IV Oral Cavity or Oropharynx Cancer Undergoing Definitive Treatment
Phase 2 Terminated
6 enrolled 22 charts
Phase 2 Study of AT13387 (Onalespib) in ALK+ ALCL, MCL, and BCL-6+ DLBCL
Phase 2 Terminated
25 enrolled 15 charts
A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer
Phase 2 Terminated
111 enrolled 15 charts
Combining CRLX101, a Nanoparticle Camptothecin, With Enzalutamide in People With Progressive Metastatic Castration Resistant Prostate Cancer Following Prior Enzalutamide Treatment
Phase 2 Terminated
4 enrolled 12 charts
Avelumab (Bavencio) With IL-15 in Subjects With Clear-Cell Renal Carcinoma
Phase 2 Terminated
2 enrolled 13 charts
Sunitinib in Sarcomas of the Central Nervous System
Phase 2 Terminated
5 enrolled 14 charts
A Phase II Study of Bintrafusp Alfa (M7824) in Checkpoint Inhibitor Naive and Refractory Subjects With Urothelial Carcinoma
Phase 2 Terminated
2 enrolled 13 charts
Duvelisib for Ibrutinib-Resistant Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Phase 2 Terminated
3 enrolled 12 charts
Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004
Phase 2 Terminated
30 enrolled 15 charts
Anti-Mesothelin Immunotoxin LMB-100 Followed by Pembrolizumab in Malignant Mesothelioma
Phase 2 Terminated
18 enrolled 15 charts
Stem Cell Transplantation for Metastatic Solid Tumors
Phase 2 Terminated
42 enrolled 11 charts
Avelumab in Combination With Hypofractionated Radiotherapy in Patients With Relapsed Refractory Multiple Myeloma
Phase 2 Terminated
4 enrolled 12 charts
Immunotherapy With E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions
Phase 2 Terminated
1 enrolled 8 charts
Study of Mutation-Targeted Therapy With Sunitinib or Everolimus in People With Advanced Low- or Intermediate-Grade Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas With or Without Cytoreductive Surgery
Phase 2 Terminated
16 enrolled 15 charts
Erlotinib Hydrochloride in Treating Patients With Bladder Cancer Undergoing Surgery
Phase 2 Terminated
50 enrolled 27 charts
Mithramycin for Lung, Esophagus, and Other Chest Cancers
Phase 2 Terminated
16 enrolled 13 charts
Ability of a Dendritic Cell Vaccine to Immunize Melanoma or Epithelial Cancer Patients Against Defined Mutated Neoantigens Expressed by the Autologous Cancer
Phase 2 Terminated
1 enrolled 7 charts
Modified Tumor Infiltrating Lymphocytes for Metastatic Melanoma
Phase 2 Terminated
2 enrolled 8 charts
Ixabepilone to Treat Cervical Cancer
Phase 2 Terminated
41 enrolled 11 charts
Phase II Study of the Efficacy and Toxicity of Ontak(Registered Trademark) (Denileukin Diftitox) in the Therapy of Adult T-Cell Leukemia
Phase 2 Terminated
17 enrolled 9 charts
Chemotherapy Followed by ESO-1 Lymphocytes and Aldesleukin to Treat Metastatic Cancer
Phase 2 Terminated
45 enrolled 15 charts
Lapatinib in Stage IV Melanoma With ERBB4 Mutations
Phase 2 Terminated
34 enrolled 11 charts
Bortezomib and Carboplatin in Treating Patients With Metastatic Pancreatic Cancer
Phase 2 Terminated
9 enrolled 2 charts
Akt Inhibitor MK2206 or Everolimus in Treating Patients With Refractory Kidney Cancer
Phase 2 Terminated
43 enrolled 12 charts
Trastuzumab in Treating Patients With Locally Advanced or Metastatic Gallbladder Cancer or Bile Duct Cancer That Cannot Be Removed by Surgery
Phase 2 Terminated
4 enrolled 6 charts
Erlotinib Hydrochloride or Crizotinib and Chemoradiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer
Phase 2 Terminated
59 enrolled 16 charts
Anti-Mesothelin Antibody Drug Conjugate Anetumab Ravtansine for Mesothelin Expressing Lung Adenocarcinoma
Phase 2 Terminated
2 enrolled 12 charts
Everolimus Therapy in People With Birt-Hogg-Dube Syndrome (BHD)-Associated Kidney Cancer or Sporadic Chromophobe Renal Cancer
Phase 2 Terminated
3 enrolled 7 charts
Azacitidine and Entinostat in Treating Patients With Stage I Non-Small Cell Lung Cancer That Has Been Removed By Surgery
Phase 2 Terminated
13 enrolled 5 charts
Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers
Phase 2 Terminated
442 enrolled 17 charts
CUDC-907 Treatment in People With Metastatic and Locally Advanced Thyroid Cancer
Phase 2 Terminated
7 enrolled 13 charts
A Phase II Study of Neo-Adjuvant Gemcitabine, Cisplatin and Bevacizumab in Stage IIIA (N2) Non-Squamous Cell Non-Small Cell Lung Cancer
Phase 2 Terminated
7 enrolled 9 charts
Sorafenib in Treating Patients Who Are Undergoing Surgery for Metastatic Kidney Cancer
Phase 2 Terminated
10 enrolled 7 charts
Metabolomic and BH3 Profiling of Esophageal Cancers: Identification of Novel Assessment Methods of Treatment Response for Precision Therapy
Phase 2 Terminated
2 enrolled 6 charts