Clinical Trials Browser

NCT01445288 2026-02-20

Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Medulloblastoma, Central Nervous System Neoplasms, Germinoma, Neuroectodermal Tumors, Primitive, Neurotoxicity Syndromes

NCT00978458 2025-09-08

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Phase 3 Active not recruiting

540 enrolled

CNS

Astrocytoma, Brain Neoplasms, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT01372774 2022-09-16

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

Phase 3 Completed

194 enrolled 11 charts

CNS

Brain Neoplasms, Neoplasm Metastasis, Radiation Injuries, Neurotoxicity Syndromes

NCT01381718 2021-08-13

Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor

Phase 2 Completed

112 enrolled 16 charts

CNS

Fatigue, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT00001807 2019-04-24

(1)H-Nuclear Magnetic Resonance Spectroscopic Imaging of the Brain in Patients Who Receive Neurotoxic Therapy

Completed

50 enrolled

CNS

Brain Neoplasms, Neurotoxicity Syndromes

NCT00452868 2018-09-07

Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

Phase EARLY_PHASE1 Completed

14 enrolled 7 charts

CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Radiation Injuries, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neurotoxicity Syndromes, Optic Nerve Glioma

NCT00566852 2017-08-21

Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors

Phase 3 Completed

554 enrolled 12 charts

CNS

Brain Neoplasms, Neoplasm Metastasis, Neurotoxicity Syndromes

NCT00734773 2012-05-18

Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL

Phase EARLY_PHASE1 Withdrawn

CNSLymphoid

Lymphoma, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT00469937 2012-02-28

Ph I Study of Lithium During Whole Brain Radiotherapy For Patients With Brain Metastases

Phase 1 Terminated

9 enrolled

CNS

Brain Neoplasms, Radiation Injuries, Central Nervous System Neoplasms, Neurotoxicity Syndromes