Clinical Trials

283 enrolled 31 charts

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Leukemia, Myeloid, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase

NCT05254743 2026-03-12

BRUIN-CLL-314

Phase 3 Recruiting

662 enrolled

Phase 1 Active not recruiting

Hematologic Diseases, Leukemia, Lymphoid, Lymphoma, Non-Hodgkin, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell

NCT05024045 2026-03-03

Study of Oral LOXO-338 in Patients With Advanced Blood Cancers

316 enrolled

LymphoidOther hematologic neoplasmPlasma cell

Hematologic Diseases, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

NCT06910969 2026-03-03

HORIZONS

350 enrolled

Graft vs Host Disease, Hematologic Diseases, Neoplasms, Neoplasms by Site, Hematologic Neoplasms

NCT03514017 2026-03-02

Ibrutinib and PD-1 Blockade in High Risk Lymphocytic Leukemia

Phase 2 Terminated

5 enrolled 11 charts

Classical hematologyDermatologicLymphoidMyeloidOther hematologic neoplasm

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT05589896 2026-02-24

A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

Phase 1/2 Recruiting

12 enrolled

Anemia, Refractory, with Excess of Blasts, Hematologic Diseases, Hodgkin Disease, Leukemia, Lymphoma, Leukemia, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Lymphoma, T-Cell, Cutaneous, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07216443 2026-02-23

Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

Phase 2 Recruiting

80 enrolled

MyeloidOther hematologic neoplasmOther neoplasm

Acute Disease, Bone Marrow Diseases, Disease, Graft vs Host Disease, Hematologic Diseases, Immune System Diseases, Immunoproliferative Disorders, Leukemia, Myelodysplastic Syndromes, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Pathologic Processes, Precancerous Conditions, Preleukemia, Syndrome, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Disease Attributes

NCT00001620 2026-02-17

Screening for Hematology Branch Protocols

Enrolling by invitation

10,000 enrolled

Classical hematologyOther hematologic neoplasm

Cytopenia, Anemia, Disease, Hematologic Diseases, Neutropenia, Thrombocytopenia, Hematologic Neoplasms

NCT04761770 2026-02-17

Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders

Phase 2 Active not recruiting

33 enrolled

Phase 2 Active not recruiting

Hematologic Diseases, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Chronic, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

NCT06001385 2026-02-05

OPTIMIZE

313 enrolled

LymphoidMyeloidOther hematologic neoplasmOther neoplasm

Bone Marrow Diseases, Hematologic Diseases, Immune System Diseases, Immunoproliferative Disorders, Leukemia, Leukemia, Lymphoid, Leukemia, Myeloid, Lymphatic Diseases, Lymphoma, Lymphoproliferative Disorders, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Precancerous Conditions, Preleukemia, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis

NCT04965493 2026-01-29

BRUIN CLL-322

Phase 3 Active not recruiting

600 enrolled

Hematologic Diseases, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell

NCT03159702 2026-01-27

Propylene Glycol-Free Melphalan HCl (EVOMELA®) in Combination With Fludarabine and Total Body Irradiation Based Reduced Intensity Conditioning for Haploidentical Transplantation

Other hematologic neoplasmPlasma cell

43 enrolled 9 charts

Hematologic Diseases, Multiple Myeloma, Hematologic Neoplasms

NCT03842696 2026-01-27

Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation

Phase 1/2 Active not recruiting

43 enrolled

Phase 3 Active not recruiting

Blast Crisis, Graft vs Host Disease, Hematologic Diseases, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Mantle-Cell

NCT05023980 2026-01-22

BRUIN CLL-313

309 enrolled

Hematologic Diseases, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell

NCT00186147 2025-12-18

Bone Marrow Grafting for Leukemia and Lymphoma

Enrolling by invitation

9,999 enrolled

Hematologic Diseases, Leukemia, Lymphoma

NCT04167683 2025-12-08

Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant

Active not recruiting

144 enrolled

Hematologic Diseases, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07200583 2025-11-18

PAIA-Haplo

Completed

50 enrolled

Hematologic Diseases, Hematologic Neoplasms

NCT03578367 2025-11-10

Study of Efficacy and Safety of Asciminib in Combination With Imatinib in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP)

104 enrolled 11 charts

Hematologic Diseases, Leukemia, Leukemia, Myeloid, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT06472089 2025-10-15

BMT-CARE

800 enrolled

MyeloidOther hematologic neoplasmOther neoplasm

Hematologic Diseases, Neoplasms, Neoplasms by Site, Hematologic Neoplasms

NCT02158858 2025-10-08

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

Phase 1/2 Completed

336 enrolled

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Precancerous Conditions, Preleukemia, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Myelodysplastic-Myeloproliferative Diseases, Primary Myelofibrosis

NCT06487247 2025-09-17

HEME Home Transfusion Program

LymphoidMyeloidOther hematologic neoplasmPlasma cell

700 enrolled

Hematologic Diseases, Leukemia, Lymphoma, Myelodysplastic Syndromes, Hematologic Neoplasms, Neoplasms, Plasma Cell

NCT05150561 2025-08-11

Muscle Dysfunction in Patients With Haematological Diseases

Active not recruiting

216 enrolled

Hematologic Diseases, Lymphoma, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03207854 2025-07-11

Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers

Recruiting

500 enrolled

Hematologic Diseases, Immune System Diseases, Neoplasms, Hematologic Neoplasms

NCT05969821 2025-06-12

CHIS

Not yet recruiting

1,000 enrolled

VEXAS syndrome, Autoimmune Diseases, Hematologic Diseases, Immune System Diseases, Inflammation, Leukemia, Lymphoma, Lymphoproliferative Disorders, Monoclonal Gammopathy of Undetermined Significance, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Juvenile, Myelodysplastic-Myeloproliferative Diseases

NCT06795815 2025-06-12

OHGW-ACP

75 enrolled

LymphoidMyeloidOther hematologic neoplasmPlasma cell

Hematologic Diseases, Leukemia, Lymphoma, Neoplasms

NCT03246906 2025-06-04

Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation

Phase 2 Terminated

150 enrolled

Blastic Plasmacytoid Dendritic Cell Neoplasm, Hematologic Diseases, Hodgkin Disease, Waldenstrom Macroglobulinemia, Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Prolymphocytic, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases

NCT04996875 2025-05-30

APEX

Phase 2 Recruiting

140 enrolled

Hematologic Diseases, Hypersensitivity, Immune Complex Diseases, Immune System Diseases, Leukemia, Leukemia, Mast-Cell, Leukemia, Myeloid, Mastocytosis, Myeloproliferative Disorders, Neoplasms, Neoplasms by Site, Neoplasms, Connective Tissue, Skin Diseases, Soft Tissue Neoplasms, Urticaria Pigmentosa, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Mastocytosis, Systemic

NCT02494258 2025-05-22

A Study to Evaluate Long-term Safety of CC-486 (Oral Azacitidine) in Subjects With Hematological Disorders

5 enrolled

Hematologic Diseases, Neoplasms, Hematologic Neoplasms

NCT03066648 2025-05-18

Study of PDR001 and/or MBG453 in Combination With Decitabine in Patients With AML or High Risk MDS

Phase 1 Completed

241 enrolled

Phase 3 Active not recruiting

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Leukemia, Myeloid, Myelodysplastic Syndromes, Preleukemia, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT04666038 2025-04-20

BRUIN CLL-321

238 enrolled 17 charts 1 FDA

Hematologic Diseases, Lymphoma, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell

NCT06904859 2025-04-01

The Role and Mechanism of TCR-T Cells in Immunotherapy for Acute Myeloid Leukemia

50 enrolled

Phase NA Active not recruiting

Hematologic Diseases, Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute

NCT06849921 2025-02-27

Precise Design of Cell Therapy for Relapsed and Refractory Hematological Tumors

200 enrolled

Phase NA Not yet recruiting

Hematologic Diseases, Hematologic Neoplasms

NCT06843291 2025-02-24

UNIVERSAL GENETIC TESTING OF PATIENTS WITH HEMATOLOGICAL MALIGNANCIES (UGT)

100 enrolled

Hematologic Diseases, Hematologic Neoplasms

NCT05172700 2024-12-18

Expanded Access Program for Pirtobrutinib for Participants With B-Cell Cancer

Approved for marketing

Hematologic Diseases, Waldenstrom Macroglobulinemia, Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Mantle-Cell

NCT04310592 2024-12-12

CYNK001AML01

Phase 1 Terminated

27 enrolled

Hematologic Diseases, Leukemia, Leukemia, Myeloid, Neoplasms, Neoplasms by Histologic Type, Leukemia, Myeloid, Acute, Neoplasm, Residual, Hematologic Neoplasms

NCT05833438 2024-12-09

VENAZA-5S

Phase 2 Recruiting

45 enrolled

Hematologic Diseases, Leukemia, Myeloid, Acute

NCT05819762 2024-12-04

Evaluation of ClearLLab LS Screening Panel

Completed

831 enrolled

Hematologic Diseases, Hematologic Neoplasms

NCT05716113 2024-11-21

CD7 CAR-T for Patients With r/r CD7+ T-ALL/T-LBL

20 enrolled

Hematologic Diseases, Neoplasms, Neoplasms by Site, Hematologic Neoplasms

NCT05902845 2024-11-21

RD13-02 CAR-T Cell Injection for Patients With r/r CD7+ T-ALL/T-LBL

4 enrolled

Hematologic Diseases, Neoplasms, Hematologic Neoplasms

NCT05907603 2024-11-21

Research Development（RD）13-02 Chimeric Antigen Receptor(CAR) -T Cell Injection for Patients With r/r Cluster Of Differentiation 7（CD7）+ T-Acute Lymphoblastic Leukemia(ALL)/T-Lymphoblastic Lymphoma(LBL) /Acute Myelogenous Leukemia(AML)

8 enrolled

Hematologic Diseases, Neoplasms, Hematologic Neoplasms

NCT06034275 2024-11-15

Study of VIP943 in Subjects With Advanced CD123+ Hematologic Malignancies

Phase 1 Recruiting

36 enrolled

Bone Marrow Diseases, Burkitt Lymphoma, Hematologic Diseases, Leukemia, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT01174615 2024-09-19

Collection of Blood and/or Bone Marrow for Investigation and Characterization of Normal and Abnormal Cell Growth

Withdrawn

Hematologic Diseases, Leukemia

NCT02760238 2024-08-27

Myeloproliferative Neoplasms (MPNs) Patient Registry

Recruiting

5,000 enrolled

CNSOther hematologic neoplasm

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Mastocytosis, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Myelomonocytic, Chronic, Hypereosinophilic Syndrome, Leukemia, Myelomonocytic, Juvenile, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT04737785 2024-08-27

Central Nervous System Disorders Following Hematopoietic Stem Cell Transplantation

Completed

252 enrolled

Central Nervous System Infections, Hematologic Diseases, Infections, Hematologic Neoplasms

NCT04298892 2024-07-01

INTHEMA

Unknown

2,000 enrolled

LymphoidOther hematologic neoplasmPlasma cell

Hematologic Diseases, Hematologic Neoplasms

NCT00457782 2024-04-25

A Phase I Safety, PK and PD Study of KW-2478 in Patients With Multiple Myeloma, Chronic Lymphocytic Leukaemia or B-cell Non-Hodgkin's Lymphoma

Phase 1 Completed

27 enrolled

Bronchiolitis Obliterans Syndrome, Hematologic Diseases, Leukemia, Lymphoma, Multiple Myeloma, Neoplasms, Leukemia, B-Cell, Lymphoma, B-Cell

NCT01063907 2024-04-25

A Study of KW-2478 in Combination With Bortezomib in Subjects With Relapsed and/or Refractory Multiple Myeloma

Phase 1/2 Completed

95 enrolled 13 charts

LymphoidOther hematologic neoplasmPlasma cell

Bronchiolitis Obliterans Syndrome, Blood Protein Disorders, Hematologic Diseases, Immune System Diseases, Immunoproliferative Disorders, Leukemia, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, Paraproteinemias, Leukemia, B-Cell, Neoplasms, Plasma Cell

NCT04601584 2024-03-06

GNR-084 Safety and Pharmacological Characteristics in Refractory or Relapse B-cell Precursor ALL

Phase 1/2 Recruiting

36 enrolled