Clinical Trials

LymphoidMyeloidOther hematologic neoplasmOther neoplasm

300 enrolled

Bone Marrow Diseases, Hematologic Diseases, Immune System Diseases, Immunoproliferative Disorders, Leukemia, Leukemia, Lymphoid, Leukemia, Myeloid, Lymphatic Diseases, Lymphoma, Lymphoproliferative Disorders, Myelodysplastic Syndromes, Neoplasms, Neoplasms by Histologic Type, Precancerous Conditions, Preleukemia, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02467270 2026-03-17

OPTIC

MyeloidOther hematologic neoplasm

283 enrolled 31 charts

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Leukemia, Myeloid, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase

NCT07387354 2026-03-16

MDS

Phase 1/2 Not yet recruiting

25 enrolled

Myeloid

Bone Marrow Diseases, Hematologic Diseases, Myelodysplastic Syndromes, Myeloproliferative Disorders

NCT05254743 2026-03-12

BRUIN-CLL-314

Phase 3 Recruiting

662 enrolled

Hematologic Diseases, Leukemia, Lymphoid, Lymphoma, Non-Hodgkin, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell

NCT04450927 2026-03-06

Data Collection of Standard Care and Evaluation of NHLBI Patients and Donors

Enrolling by invitation

10,000 enrolled

Hematologic Diseases, Neoplasms

NCT05186753 2026-03-04

(Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis

Phase 1 Active not recruiting

237 enrolled

Myeloid

Hematologic Diseases, Hypersensitivity, Immune Complex Diseases, Immune System Diseases, Mastocytosis, Mastocytosis, Systemic

NCT05024045 2026-03-03

Study of Oral LOXO-338 in Patients With Advanced Blood Cancers

316 enrolled

LymphoidOther hematologic neoplasmPlasma cell

Hematologic Diseases, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

NCT06910969 2026-03-03

HORIZONS

350 enrolled

Graft vs Host Disease, Hematologic Diseases, Neoplasms, Neoplasms by Site, Hematologic Neoplasms

NCT03514017 2026-03-02

Ibrutinib and PD-1 Blockade in High Risk Lymphocytic Leukemia

Phase 2 Terminated

5 enrolled 11 charts

Classical hematologyDermatologicLymphoidMyeloidOther hematologic neoplasm

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT06963216 2026-02-27

A Study Investigating Coagadex in the Treatment AFXD Associated With AL Amyloidosis

Phase 3 Recruiting

15 enrolled

Plasma cell

Immunoglobulin Light-chain Amyloidosis, Blood Coagulation Disorders, Factor X Deficiency, Hematologic Diseases, Hemorrhagic Disorders

NCT05589896 2026-02-24

A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

Phase 1/2 Recruiting

12 enrolled

Anemia, Refractory, with Excess of Blasts, Hematologic Diseases, Hodgkin Disease, Leukemia, Lymphoma, Leukemia, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Lymphoma, T-Cell, Cutaneous, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00001620 2026-02-17

Screening for Hematology Branch Protocols

Enrolling by invitation

10,000 enrolled

Classical hematologyOther hematologic neoplasm

Cytopenia, Anemia, Disease, Hematologic Diseases, Neutropenia, Thrombocytopenia, Hematologic Neoplasms

NCT04761770 2026-02-17

Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders

MyeloidOther hematologic neoplasm

33 enrolled

Hematologic Diseases, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Chronic, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

NCT06001385 2026-02-05

OPTIMIZE

LymphoidMyeloidOther hematologic neoplasmOther neoplasm

313 enrolled

Bone Marrow Diseases, Hematologic Diseases, Immune System Diseases, Immunoproliferative Disorders, Leukemia, Leukemia, Lymphoid, Leukemia, Myeloid, Lymphatic Diseases, Lymphoma, Lymphoproliferative Disorders, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Precancerous Conditions, Preleukemia, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis

NCT07379125 2026-01-30

Therapeutic RSK1 Targeting in Myelofibrosis

Phase 1 Not yet recruiting

18 enrolled

Classical hematologyMyeloid

Anemia, Bone Marrow Diseases, Hematologic Diseases, Myeloproliferative Disorders, Splenomegaly, Bone Marrow Neoplasms, Primary Myelofibrosis

NCT04965493 2026-01-29

BRUIN CLL-322

Phase 3 Active not recruiting

600 enrolled

Hematologic Diseases, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell

NCT01287000 2026-01-28

Gulf Long-Term Follow-Up Study

Active not recruiting

32,658 enrolled

Psychological Well-Being, Cardiovascular Diseases, Hematologic Diseases, Immune System Diseases, Neoplasms, Respiratory Aspiration

NCT03159702 2026-01-27

Propylene Glycol-Free Melphalan HCl (EVOMELA®) in Combination With Fludarabine and Total Body Irradiation Based Reduced Intensity Conditioning for Haploidentical Transplantation

Other hematologic neoplasmPlasma cell

43 enrolled 9 charts

Hematologic Diseases, Multiple Myeloma, Hematologic Neoplasms

NCT03842696 2026-01-27

Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation

Phase 1/2 Active not recruiting

43 enrolled

Blast Crisis, Graft vs Host Disease, Hematologic Diseases, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Mantle-Cell

NCT04180059 2026-01-26

CTL-DP 01

Phase NA Enrolling by invitation

6 enrolled

Hematologic Diseases

NCT05443321 2026-01-23

Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes

1,006 enrolled

GastrointestinalGenitourinary

Arrhythmias, Cardiac, Asthma, Cardiovascular Diseases, Gastrointestinal Diseases, Heart Failure, Hematologic Diseases, Infections, Kidney Diseases, Nervous System Diseases, Rheumatic Diseases, Shock, Urologic Diseases, Critical Illness, Renal Insufficiency

NCT07364409 2026-01-23

ReSTORE

Phase NA Active not recruiting

5 enrolled

Azoospermia, Nonobstructive, Hematologic Diseases, Infertility, Male, Neoplasms

NCT05023980 2026-01-22

BRUIN CLL-313

Phase 3 Active not recruiting

309 enrolled

Hematologic Diseases, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell

NCT01352520 2026-01-20

SGN-35 in CD30-positive Lymphoproliferative Disorders (ALCL), Mycosis Fungoides (MF), and Extensive Lymphomatoid Papulosis (LyP)

79 enrolled

DermatologicLymphoid

Hematologic Diseases, Lymphoma, Mycosis Fungoides, Lymphoma, T-Cell, Cutaneous, Lymphomatoid Papulosis, Lymphoma, Primary Cutaneous Anaplastic Large Cell

NCT04640987 2026-01-08

Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Adults With T-allo10 Cells Addback

22 enrolled

Hematologic Diseases

NCT05228470 2026-01-06

A Study of Elranatamab (PF-06863135) in Chinese Participants With Refractory Multiple Myeloma.

39 enrolled 15 charts

LymphoidPlasma cell

Blood Protein Disorders, Cardiovascular Diseases, Hematologic Diseases, Hemorrhagic Disorders, Immune System Diseases, Immunoproliferative Disorders, Lymphoproliferative Disorders, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Paraproteinemias, Vascular Diseases, Hemostatic Disorders, Neoplasms, Plasma Cell

NCT04572815 2026-01-02

Ustekinumab for the Prevention of Acute Graft-versus-Host Disease After Unrelated Donor Hematopoietic Cell Transplant

Phase 2 Not yet recruiting

116 enrolled

Hematologic Diseases

NCT07303881 2025-12-26

JACKPOT22

16 enrolled

Thoracic

Hematologic Diseases, Lung Neoplasms, Neoplasm Metastasis

NCT05317416 2025-12-22

MagnetisMM-7

Phase 3 Active not recruiting

811 enrolled

Plasma cell

Hematologic Diseases, Multiple Myeloma

NCT00186147 2025-12-18

Bone Marrow Grafting for Leukemia and Lymphoma

Enrolling by invitation

9,999 enrolled

Hematologic Diseases, Leukemia, Lymphoma

NCT07257640 2025-12-10

IL-5 CAR-T Cell Therapy for Refractory/Relapsed Eosinophilic Leukemia

20 enrolled

Hematologic Diseases, Neoplasms

NCT04167683 2025-12-08

Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant

Active not recruiting

144 enrolled

Hematologic Diseases, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06559189 2025-11-28

CD19x22 Chimeric Antigen Receptor T-cell Therapy (CAR T) in Pediatric B-ALL

53 enrolled

Lymphoid

Burkitt Lymphoma, Hematologic Diseases, Recurrence

NCT07200583 2025-11-18

PAIA-Haplo

Completed

50 enrolled

Hematologic Diseases, Hematologic Neoplasms

NCT03578367 2025-11-10

Study of Efficacy and Safety of Asciminib in Combination With Imatinib in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP)

MyeloidOther hematologic neoplasm

104 enrolled 11 charts

Hematologic Diseases, Leukemia, Leukemia, Myeloid, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT06472089 2025-10-15

BMT-CARE

800 enrolled

MyeloidOther hematologic neoplasmOther neoplasm

Hematologic Diseases, Neoplasms, Neoplasms by Site, Hematologic Neoplasms

NCT02158858 2025-10-08

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

Phase 1/2 Completed

336 enrolled

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Precancerous Conditions, Preleukemia, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Myelodysplastic-Myeloproliferative Diseases, Primary Myelofibrosis

NCT03356171 2025-10-02

APACCHE

Phase NA Completed

80 enrolled

Hematologic Diseases, Motor Activity, Neoplasms

NCT06095752 2025-10-02

Multiple Myeloma Prognostic Indices

Completed

48 enrolled

Plasma cell

Hematologic Diseases, Multiple Myeloma

NCT01909934 2025-09-19

Study of Brentuximab Vedotin in Participants With Relapsed or Refractory Systemic Anaplastic Large Cell Lymphoma

Phase 4 Completed

50 enrolled 22 charts

Lymphoid

Hematologic Diseases, Lymphoma, Lymphoma, Non-Hodgkin, Recurrence, Lymphoma, Large-Cell, Anaplastic

NCT06487247 2025-09-17

HEME Home Transfusion Program

LymphoidMyeloidOther hematologic neoplasmPlasma cell

700 enrolled

Hematologic Diseases, Leukemia, Lymphoma, Myelodysplastic Syndromes, Hematologic Neoplasms, Neoplasms, Plasma Cell

NCT07075185 2025-09-02

inMMyCAR

40 enrolled

LymphoidPlasma cell

Blood Protein Disorders, Disease, Hematologic Diseases, Immune System Diseases, Immunoproliferative Disorders, Lymphoproliferative Disorders, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Paraproteinemias, Vascular Diseases, Hemostatic Disorders

NCT05827835 2025-08-13

CD7 CAR-T Bridging to alloHSCT for R/R CD7+Malignant Hematologic Diseases

Phase 1/2 Recruiting

30 enrolled

Hematologic Diseases, Neoplasms

NCT05150561 2025-08-11

Muscle Dysfunction in Patients With Haematological Diseases

Active not recruiting

216 enrolled

Classical hematologyMyeloid

Hematologic Diseases, Lymphoma, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07108023 2025-08-06

EHPVO-HEM

Not yet recruiting

115 enrolled

Anemia, Hematologic Diseases, Hemoglobinuria, Paroxysmal, Hypersplenism, Leukopenia, Myeloproliferative Disorders, Thrombocytopenia, Antiphospholipid Syndrome, Thrombophilia

NCT03207854 2025-07-11

Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers

Recruiting

500 enrolled

Hematologic Diseases, Immune System Diseases, Neoplasms, Hematologic Neoplasms

NCT04848493 2025-06-13

VAX4FRAIL

Completed

747 enrolled

COVID-19, Hematologic Diseases, Nervous System Diseases, Rheumatic Diseases

NCT05969821 2025-06-12

CHIS

Not yet recruiting

1,000 enrolled

VEXAS syndrome, Autoimmune Diseases, Hematologic Diseases, Immune System Diseases, Inflammation, Leukemia, Lymphoma, Lymphoproliferative Disorders, Monoclonal Gammopathy of Undetermined Significance, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Juvenile, Myelodysplastic-Myeloproliferative Diseases

NCT06795815 2025-06-12

OHGW-ACP

75 enrolled