Clinical Trials Browser

NCT00001452 2026-03-13

Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex

Completed

1,387 enrolled

Endocrine

Cushing Syndrome, Peutz-Jeghers Syndrome, Pituitary Neoplasms, Carney Complex

NCT00005927 2026-02-25

Study of Adrenal Gland Tumors

Completed

690 enrolled

Endocrine

Adrenal Gland Neoplasms, Cushing Syndrome

NCT03604198 2026-02-19

Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome

Phase 2 Active not recruiting

125 enrolled

Endocrine

ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Cushing Syndrome, Diabetes Mellitus, Type 2, Hypertension, Adrenocortical Carcinoma, Pituitary ACTH Hypersecretion

NCT07412782 2026-02-17

REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD)

Phase NA Recruiting

100 enrolled

EndocrineOther

Bone Diseases, Metabolic, Cushing Syndrome, Dwarfism, Pituitary, Neoplasms, Obesity, Osteogenesis Imperfecta, Osteoporosis, Malnutrition, Overweight

NCT07296484 2026-02-12

CAPTAIN-T2D

Phase 2 Recruiting

1,500 enrolled

ACTH Syndrome, Ectopic, Cushing Syndrome, Diabetes Mellitus, Type 2

NCT07361874 2026-01-23

IMPACT-MACS

Phase NA Not yet recruiting

75 enrolled

Adrenal incidentaloma, ACTH Syndrome, Ectopic, Cushing Syndrome, Insulin Resistance, Weight Loss

NCT07247162 2025-12-10

LINC CARE

Phase 4 Not yet recruiting

63 enrolled

ACTH Syndrome, Ectopic, Cushing Syndrome, Hypertension

NCT05307328 2025-10-08

RESCUE

Phase 2 Completed

26 enrolled

Endocrine

ACTH Syndrome, Ectopic, Cushing Syndrome, Pituitary ACTH Hypersecretion

NCT06106295 2025-09-22

Metyrapone for Mild Autonomous Cortisol Secretion (MACS)

Phase 2 Active not recruiting

30 enrolled

ACTH Syndrome, Ectopic, Adrenal Hyperplasia, Congenital, Cushing Syndrome

NCT00669266 2025-08-26

Adrenal Tumors - Pathogenesis and Therapy

Recruiting

500 enrolled

Endocrine

Adrenal Gland Neoplasms, Cushing Syndrome, Hyperaldosteronism, Pheochromocytoma, Adrenocortical Carcinoma

NCT07138274 2025-08-22

Metyrapone Study for Patients Diagnosed With Mild Autonomous Cortisol Secretion - MACS

Phase 2 Not yet recruiting

90 enrolled

ACTH Syndrome, Ectopic, Adrenal Hyperplasia, Congenital, Cushing Syndrome

NCT03697109 2025-07-16

GRACE

Phase 3 Completed

152 enrolled 28 charts

Endocrine

ACTH Syndrome, Ectopic, Cushing Syndrome, Diabetes Mellitus, Type 2, Hypertension, Pituitary ACTH Hypersecretion

NCT05804669 2025-04-10

A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome

Phase 1/2 Recruiting

18 enrolled

Endocrine

ACTH Syndrome, Ectopic, Cushing Syndrome, Pituitary ACTH Hypersecretion

NCT04127552 2025-03-28

ITACA

Recruiting

68 enrolled

Endocrine

Adrenal incidentaloma, Adrenal Gland Neoplasms, Cushing Syndrome

NCT06701838 2024-12-03

OPTIMAL

Not yet recruiting

15 enrolled

Endocrine

Cushing Syndrome, Pituitary Neoplasms, Pituitary ACTH Hypersecretion, ACTH-Secreting Pituitary Adenoma

NCT05368090 2024-11-08

Endoscopic Ultrasound-guided Radiofrequency Ablation in Primary Aldosteronism

Phase NA Recruiting

60 enrolled

Endocrine

Cushing Syndrome, Hyperaldosteronism, Adrenocortical Adenoma

NCT06326853 2024-06-11

Neuroendocrine Mechanisms in Adiposity: An Integrated Approach to the Characterization of Potential Pharmacological Novel Targets Based on Experimental and Clinical Models

Not yet recruiting

200 enrolled

EndocrineOther

Acromegaly, Cushing Syndrome, Endocrine System Diseases, Hypopituitarism, Obesity, Pituitary Neoplasms

NCT06229405 2024-03-04

Development of Clinical Evidence for Optimal Management of Adrenal Diseases Based on Real-World Data

Unknown

8,200 enrolled

Endocrine

Adrenal Gland Neoplasms, Cushing Syndrome, Hyperaldosteronism, Pheochromocytoma, Adrenocortical Carcinoma

NCT04373265 2024-02-23

Study of Relacorilant in Combination With Pembrolizumab for Patients With Adrenocortical Carcinoma Which Produces Too Much Stress Hormone (Cortisol)

Phase 1 Completed

15 enrolled

Endocrine

ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Adrenal Gland Diseases, Adrenocortical Hyperfunction, Cushing Syndrome, Diabetes Mellitus, Type 2, Endocrine System Diseases, Hyperglycemia, Hypertension, Pathologic Processes, Glucose Intolerance, Adrenocortical Carcinoma

NCT05456997 2023-10-16

LYDIA

Terminated

1 enrolled

Endocrine

Cushing Syndrome, Hyperaldosteronism, Pheochromocytoma

NCT06050057 2023-09-22

Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted Adrenalectomy

Recruiting

100 enrolled

Endocrine

Adrenal Cortex Diseases, Adrenal Cortex Neoplasms, Adrenal Gland Diseases, Adrenal Gland Neoplasms, Adrenal Hyperplasia, Congenital, Cushing Syndrome, Pheochromocytoma, Adrenocortical Adenoma, Adrenocortical Carcinoma

NCT05347979 2023-02-09

Effect of Relacorilant on the Pharmacokinetics of the Sensitive P-glycoprotein Substrate Dabigatran Etexilate in Healthy Participants

Phase 1 Completed

30 enrolled

Cushing Syndrome, Neoplasms

NCT04890444 2022-02-14

CASE

Recruiting

2,000 enrolled

Endocrine

Adrenal incidentaloma, ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Adrenal Insufficiency, Adrenal Hyperplasia, Congenital, Cushing Syndrome, Hyperaldosteronism, Pheochromocytoma

NCT04433819 2020-06-16

Nailfold Capillaroscopy Evaluation in Cushing Syndrome Patients

Unknown

200 enrolled

Endocrine

ACTH Syndrome, Ectopic, Cushing Syndrome, Pituitary ACTH Hypersecretion

NCT02468193 2020-05-06

Study of Efficacy and Safety of Osilodrostat in Cushing's Syndrome

Phase 2 Completed

9 enrolled 22 charts

Acth-Independent Macronodular Adrenal Hyperplasia, ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Cushing Syndrome

NCT03474237 2020-03-18

A Prospective Cohort Study for Patients With Adrenal Diseases

Enrolling by invitation

1,500 enrolled

Endocrine

Adrenal incidentaloma, ACTH Syndrome, Ectopic, Cushing Syndrome, Hyperaldosteronism, Pheochromocytoma, Adrenocortical Carcinoma

NCT02804750 2019-10-15

Study to Evaluate CORT125134 in Participants With Cushing's Syndrome

Phase 2 Completed

35 enrolled 13 charts

Endocrine

ACTH Syndrome, Ectopic, Adrenal Cortex Neoplasms, Cushing Syndrome, Diabetes Mellitus, Type 2, Hypertension, Adrenocortical Carcinoma, Pituitary ACTH Hypersecretion

NCT02001051 2018-06-14