Clinical Trials

Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT05967689 2026-03-10

REZILIENT2

Phase 3 Active not recruiting

220 enrolled

Carcinoma, Lung Diseases

NCT05973773 2026-03-10

REZILIENT3

285 enrolled

Phase 2 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Diseases

NCT04222972 2026-03-05

AcceleRET-Lung

Phase 3 Terminated

223 enrolled 18 charts

Head & NeckThoracic

Adenocarcinoma, Bronchial Diseases, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT05941897 2026-03-05

LOTOS

39 enrolled

Phase 2 Active not recruiting

Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT03598309 2026-02-27

Phase II Trial to Modulate Intermediate Endpoint Biomarkers in Former and Current Smokers

19 enrolled

Lung Diseases, Lung Neoplasms

NCT04676828 2026-02-24

ASPECT

90 enrolled

Abnormalities, Radiation-Induced, Lung Diseases, Lung Neoplasms, Respiratory Insufficiency, Radiation Pneumonitis

NCT00001465 2026-02-20

Study of the Disease Process of Lymphangioleiomyomatosis

2,000 enrolled

Lung Diseases, Pneumothorax, Tuberous Sclerosis, Lymphangioleiomyomatosis

NCT02984761 2026-02-19

VALOR

670 enrolled

Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT06728709 2026-02-19

Lung Ultrasound in Critically Ill Obstetrics and Gynecological Patients

64 enrolled

Lung Diseases

NCT00001532 2026-02-17

Role of Genetic Factors in the Development of Lung Disease

3,500 enrolled

Asthma, Cystic Fibrosis, Lung Diseases, Pulmonary Fibrosis, Tuberous Sclerosis, Sarcoidosis, Pulmonary, alpha 1-Antitrypsin Deficiency

NCT06765109 2026-02-17

ALKAZAR

Phase 3 Recruiting

450 enrolled

Phase 1/2 Not yet recruiting

Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms

NCT07407933 2026-02-12

A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors

118 enrolled

Lung Diseases, Thoracic Neoplasms, Small Cell Lung Carcinoma

NCT06494241 2026-01-30

Small/Middle Tier Cities and County Lung Cancer Quality Improvement Project (QIP) Study

Active not recruiting

1,000 enrolled

Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT06523270 2026-01-15

Advanced Imaging Holistic Omics Biobank

50,000 enrolled

Cardiovascular Diseases, Lung Diseases, Nervous System Diseases

NCT05854563 2026-01-13

CC1

2,000 enrolled

Lung Diseases, Lung Diseases, Obstructive, Lung Neoplasms, Pneumonia, Lung Diseases, Interstitial

NCT06376084 2026-01-08

FOREFRONT

Active not recruiting

532 enrolled

Phase 1/2 Active not recruiting

Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT03899792 2026-01-06

LIBRETTO-121

36 enrolled 13 charts 2 FDA

BreastCNSEndocrineGastrointestinalHead & NeckSarcomaThoracic

Thyroid Cancer, Papillary, Breast Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Sarcoma, Thoracic Neoplasms, Thyroid Diseases, Thyroid Neoplasms, Central Nervous System Neoplasms, Myofibromatosis, Carcinoma, Medullary

NCT06841874 2025-12-24

Tale EAP

No longer available

Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT04657120 2025-12-23

HYDRA

Phase 4 Not yet recruiting

698 enrolled

Cardiovascular Diseases, Disease, Embolism, Lung Diseases, Neoplasms, Pulmonary Embolism, Respiratory Tract Diseases, Vascular Diseases, Embolism and Thrombosis

NCT07279935 2025-12-12

REVIVE

100 enrolled

Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT06758700 2025-12-05

Post-line Treatment With Teniposide for c-Myc-driven Extensive-stage Small Cell Lung Cancer

15 enrolled

Lung Diseases, Lung Neoplasms, Thoracic Neoplasms, Small Cell Lung Carcinoma

NCT07165691 2025-12-02

TELESCOPE-H

91 enrolled

Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT04614129 2025-11-24

Lung Cancer Risk and Early Detection in Firefighters

734 enrolled

Lung Diseases, Lung Neoplasms

NCT06145750 2025-11-24

FIRSTLUNG

28 enrolled

Adenocarcinoma, Disease, Lung Diseases, Lung Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT06917573 2025-11-19

PALACE

63 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT04614103 2025-11-12

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

170 enrolled

Phase 1/2 Active not recruiting

Bronchial Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms

NCT03157128 2025-10-20

LIBRETTO-001

857 enrolled 3 FDA

BreastCNSEndocrineGastrointestinalHead & NeckThoracic

Thyroid Cancer, Papillary, Breast Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms, Thyroid Diseases, Thyroid Neoplasms, Central Nervous System Neoplasms, Carcinoma, Medullary

NCT07162883 2025-09-09

Pharmacokinetic Study of QL2107 Versus Keytruda® for Adjuvant Therapy of Non-Small Cell Lung Cancer (NSCLC)

Phase 3 Not yet recruiting

122 enrolled

Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Lymphatic Metastasis, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT07126626 2025-08-17

Validation of the SPOT-MAS Lung Test Using Circulating Tumor DNA for the Detection of Lung Cancer

Not yet recruiting

1,184 enrolled

Lung Diseases

NCT06546839 2025-08-06

SPSIPB vs SAPB for Thoracoscopic Surgery

50 enrolled

Lung Diseases, Lung Neoplasms, Thoracic Diseases, Thoracic Neoplasms

NCT07107893 2025-08-06

Comparison of Double Lumen Tube Location Verification Techniques in Single Lung Ventilation

Completed

93 enrolled

Lung Diseases, Lung Neoplasms

NCT04702165 2025-07-29

Image - Navigated Resection of Lung Nodules

Phase 1/2 Completed

25 enrolled

EndocrineGastrointestinalHead & NeckNETSarcomaThoracic

Lung Diseases, Lung Neoplasms

NCT03093116 2025-07-10

TRIDENT-1

Phase 1/2 Recruiting

500 enrolled 2 FDA

Adenocarcinoma, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Colonic Diseases, Colonic Neoplasms, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Sarcoma, Thoracic Neoplasms, Thyroid Diseases, Thyroid Neoplasms, Neuroectodermal Tumors, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT07026110 2025-06-18

Clinical Application Study of PET/CT for Differential Diagnosis of Non-small Cell Lung Cancer

590 enrolled 58 charts 5 FDA

100 enrolled

GastrointestinalThoracic

Colorectal Cancer, Hereditary Nonpolyposis, Type 8, Lung Diseases, Lung Neoplasms, Pneumonia

NCT03037385 2025-05-31

ARROW

Phase 1/2 Completed

EndocrineGastrointestinalHead & NeckNETThoracic

Thyroid Cancer, Papillary, Adenocarcinoma, Adenocarcinoma, Papillary, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms, Thyroid Diseases, Thyroid Neoplasms, Colorectal Neoplasms, Neuroectodermal Tumors, Carcinoma, Medullary, Carcinoma, Neuroendocrine, Neuroendocrine Tumors, Multiple Endocrine Neoplasia Type 2a

NCT06988943 2025-05-30

Early Intervention Strategies for Lung Cancer

16,000 enrolled

Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT03767517 2025-05-23

A Culturally-Based Palliative Care Tele-consult Program for Rural Southern Elders

209 enrolled 16 charts

Genitourinary

Digestive System Diseases, Heart Diseases, Kidney Diseases, Lung Diseases, Neoplasms, Sepsis, Stroke

NCT06964698 2025-05-09

Optimizing Post-Thoracotomy Pain Management: Comparing Erector Spinae vs. Paravertebral Block in Thoracotomy Patients

Completed

60 enrolled

Lung Diseases, Lung Neoplasms

NCT03803787 2025-05-01

Prophylactic Inhaled Steroids to Reduce Radiation Pneumonitis Frequency and Severity in Lung Cancer Patients

72 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Radiation Fibrosis Syndrome, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms, Radiation Pneumonitis, Lung Injury

NCT04165564 2025-04-30

DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers

Active not recruiting

85 enrolled

Lung Diseases

NCT04774952 2025-04-15

Dose Escalation of RMC-5552 Monotherapy in Relapsed/Refractory Solid Tumors

Phase 1 Completed

58 enrolled

Urinary Bladder Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Melanoma, Neoplasms, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Hereditary Sensory and Autonomic Neuropathies, Ovarian Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Skin Neoplasms, Thoracic Neoplasms, Uterine Neoplasms, Neoplasms, Squamous Cell

NCT06923098 2025-04-11

PET/CT GUIDED BIOPSY VERSUS CT GUIDED BIOPSY IN EVALUATION OF SUSPECTED LUNG NEOPLASMS

Phase 3 Active not recruiting

108 enrolled

Lung Diseases

NCT04564157 2025-04-10

NADIM-ADJUVANT

210 enrolled

Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT06431633 2025-04-10

ARIAN

Phase 3 Recruiting

129 enrolled

Phase 2 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Diseases

NCT05012254 2025-04-09

NIVIPI-Brain

71 enrolled

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms

NCT04066153 2025-04-06

Patient Reported Unmet Needs for Function and Supportive Occupational- and Physiotherapy Rehabilitation Interventions

Completed

43 enrolled

Genitourinary

Heart Failure, Kidney Diseases, Liver Diseases, Lung Diseases, Neoplasms, Nervous System Diseases

NCT04512430 2025-04-02

Neo-DIANA: Neoadjuvant Treatment for EGFR Mutated Patients

Phase 2 Terminated

4 enrolled 9 charts