Announcements Trials
Browse Landscape Eligibility

Clinical Trials

141 trials
RecentStart dateEnrollment
NSCLC × Clear all

Phase

Phase 2 61Phase NA 12Phase 3 12Phase 1 9Phase 1/2 8Phase 2/3 7Phase 4 5Phase EARLY_PHASE1 1

Status

Unknown 38Recruiting 32Completed 27Not yet recruiting 18Terminated 11Active not recruiting 11Withdrawn 3Suspended 1

Sponsor Class

OTHER 96INDUSTRY 41OTHER_GOV 2NETWORK 2

Study Type

Interventional 115Observational 26

Sponsor

Cancer Type

Thoracic 141Other solid neoplasm 1

Conditions

Breast Neoplasms 10998Neoplasms 8807Carcinoma, Non-Small-Cell Lung 5711Prostatic Neoplasms 5278Colorectal Neoplasms 4951Lung Neoplasms 4210Pancreatic Neoplasms 3003Multiple Myeloma 3001Neoplasm Metastasis 2954Leukemia, Myeloid, Acute 2927Carcinoma, Hepatocellular 2734Ovarian Neoplasms 2657Melanoma 2635Stomach Neoplasms 2567Lymphoma 2502Head and Neck Neoplasms 2162Recurrence 2132Precursor Cell Lymphoblastic Leukemia-Lymphoma 2069Leukemia 1992Brain Neoplasms 1971Colonic Neoplasms 1939Lymphoma, Non-Hodgkin 1894Rectal Neoplasms 1846Uterine Cervical Neoplasms 1806Glioblastoma 1699Leukemia, Lymphocytic, Chronic, B-Cell 1663Carcinoma, Renal Cell 1597Squamous Cell Carcinoma of Head and Neck 1550Lymphoma, Follicular 1526Esophageal Neoplasms 1516

Interventions

osimertinib 11Pemetrexed 10Carboplatin 10aflutinib 8Gefitinib 7Drug Therapy 7Radiotherapy 6anlotinib 5Docetaxel 5Cisplatin 5pembrolizumab 4icotinib 4Vinorelbine 4Radiosurgery 4Paclitaxel 4Gemcitabine 4Erlotinib Hydrochloride 4tislelizumab 3apatinib 3HM781-36B 3toripalimab 2spartalizumab 2dacomitinib 2camrelizumab 2Tyrosine Kinase Inhibitors 2Thalidomide 2Surgical Procedures, Operative 2S 1 (combination) 2Platinum 2Immune Checkpoint Inhibitors 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements
NCT05798845 2026-03-11

The Effect of Toripalimab Plus Radiotherapy in Patients With Operable Stage II-IIIA (N+) Non Small Cell Lung Cancer

Shanghai Chest Hospital

Phase 2 Recruiting
124 enrolled
Thoracic

NSCLC

NCT05636267 2026-03-09

Study of AK119 and AK112 With or Without Chemotherapy for NSCLC Patients

Akeso

Phase 1/2 Terminated
59 enrolled
Thoracic

NSCLC

NCT04318938 2026-03-02

Advancing Brigatinib Properties in ALK+ NSCLC Patients by Deep Phenotyping

Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest

Phase 2 Active not recruiting
118 enrolled
Thoracic

NSCLC

NCT05378763 2026-02-18

PINNACLE

Spectrum Pharmaceuticals, Inc

Phase 3 Suspended
268 enrolled
Thoracic

NSCLC

NCT07413952 2026-02-17

Limertinib Plus Radiotherapy for EGFR-Mutant NSCLC With Brain Metastases

The First Affiliated Hospital of Guangzhou Medical University

Phase 2 Not yet recruiting
45 enrolled
Thoracic

NSCLC

NCT05714891 2026-02-12

Neoadjuvant Platform Trial in Non-Small Cell Lung Cancer

Canadian Cancer Trials Group

Phase 2 Active not recruiting
4 enrolled
Thoracic

NSCLC

NCT07082179 2026-02-11

A Prospective Phase II Clinical Study of Immunotherapy Combined With Chemotherapy for Stage III Unresectable Non-small Cell Lung Cancer

Jiangsu Cancer Institute & Hospital

Phase 2 Recruiting
33 enrolled
Thoracic

NSCLC

NCT06738160 2026-02-06

The Efficacy and Safety of Narlumosbart in Combination With Stereotactic Body Radiation Therapy to Improve the Efficacy of First-line Chemotherapy Combined With Immunotherapy in Patients With Bone Metastases From Advanced Non-small Cell Lung Cancer

Fudan University

Phase 2 Recruiting
27 enrolled
Thoracic

NSCLC

NCT07388771 2026-02-05

Prediction of Outcome to Neoadjuvant Therapy in Non-small Cell Lung Cancer(NSCLC)

Tongji Hospital

Recruiting
500 enrolled
Thoracic

NSCLC

NCT07376382 2026-02-02

SYNSTAR-02

CSPC Megalith Biopharmaceutical Co.,Ltd.

Phase 3 Not yet recruiting
450 enrolled
Thoracic

NSCLC

NCT07379398 2026-01-30

Iparomlimab and Tuvonralimab Injection Combined With SBRT in Patients With Early-Stage Non-Small Cell Lung Cancer

Tianjin Medical University Cancer Institute and Hospital

Phase 2 Not yet recruiting
28 enrolled
Thoracic

NSCLC

NCT04557007 2026-01-29

Oncomabs

Oslo University Hospital

Terminated
80 enrolled
Thoracic

NSCLC

NCT07358689 2026-01-22

Toripalimab Combined With Platinum-based Chemotherapy With or Without H1 Receptor Antagonist in the Perioperative Treatment of Resectable Non-small Cell Lung Cancer

Tianjin Medical University Cancer Institute and Hospital

Phase 2 Not yet recruiting
120 enrolled
Thoracic

NSCLC

NCT06576635 2026-01-20

LUNG-05

University of Illinois at Chicago

Phase NA Recruiting
29 enrolled
Thoracic

NSCLC

NCT05089916 2026-01-14

ROSE

AIO-Studien-gGmbH

Phase 2 Active not recruiting
42 enrolled
Thoracic

NSCLC

NCT07330037 2026-01-09

TALENT Study: Phase II Trial of Adjuvant L-TIL Plus Tislelizumab in Resectable NSCLC Without pCR After Neoadjuvant Chemoimmunotherapy

Tianjin Medical University Cancer Institute and Hospital

Phase 2 Recruiting
41 enrolled
Thoracic

NSCLC

NCT04640259 2025-12-18

EoYLC

Addario Lung Cancer Medical Institute

Active not recruiting
250 enrolled
Thoracic

NSCLC

NCT07169552 2025-12-17

HC010 in First-line PD-L1 Positive Advanced NSCLC Patients

HC Biopharma Inc.

Phase 2 Recruiting
50 enrolled
Thoracic

NSCLC

NCT07281209 2025-12-15

A Study of SHR-A1811 Combined With Adebelimumab as Neoadjuvant Therapy for Resectable HER2-Altered Non-Small Cell Lung Cancer

Shanghai Chest Hospital

Phase 2 Not yet recruiting
40 enrolled
Thoracic

NSCLC

NCT07247227 2025-11-25

Real-world First-line Sugemalimab-Chemotherapy in Advanced NSCLC

Peking Union Medical College

Phase NA Recruiting
150 enrolled
Thoracic

NSCLC

NCT07243899 2025-11-24

Multimodal Model Predicts Treatment Efficacy and CIP Risk in Advanced NSCLC With Immunotherapy and Chemotherapy

Shanghai Zhongshan Hospital

Completed
3,000 enrolled
Thoracic

NSCLC

NCT04858958 2025-11-19

FAVOUR

Allist Pharmaceuticals, Inc.

Phase 1 Active not recruiting
30 enrolled
Thoracic

NSCLC

NCT05466149 2025-11-19

Efficacy and Safety of Furmonertinib in Patients With Locally Advanced or Metastatic NSCLC With EGFR Exon 20 Insertion

Allist Pharmaceuticals, Inc.

Phase 2 Active not recruiting
100 enrolled
Thoracic

NSCLC

NCT07198217 2025-09-30

Real World Study of Platinum Containing Dual Drug Chemotherapy Followed by Large Fractionated Radiotherapy Combined withTislelizumab in Stage IIIB/C-IV Non-small Cell Lung Cancer Patient

Zibo Municipal Hospital

Phase 2 Recruiting
20 enrolled
Thoracic

NSCLC

NCT06448910 2025-09-24

Cadonilimab(AK104) Plus Concurrent Chemoradiotherapy in Patients With Locally Advanced, Unresectable, Stage III NSCLC

Fudan University

Phase 2 Active not recruiting
41 enrolled
Thoracic

NSCLC

NCT07179445 2025-09-17

Analysis of Deoxyribonucleic Acid and Ribonucleic Acid Next-Generation Sequencing in Non-Small Cell Lung Cancer Patients Without Pathological Complete Response Following Neoadjuvant Immunotherapy

Tianjin Medical University Cancer Institute and Hospital

Not yet recruiting
300 enrolled
Thoracic

NSCLC

NCT06865339 2025-09-10

TRIPL

Albert Einstein College of Medicine

Phase 2 Recruiting
76 enrolled
Thoracic

NSCLC

NCT07156604 2025-09-05

Vebreltinib for Neoadjuvant in METex 14 Skipping Mutant Stage IIA-IIIB (N2) Non-small Cell Lung Cancer (NSCLC)

Fudan University

Phase 2 Not yet recruiting
30 enrolled
Thoracic

NSCLC

NCT07153770 2025-09-04

Bozitinib Combined With Chemotherapy as Radical Treatment for Stage IIA-IIIC MET-Altered Non-Small Cell Lung Cancer

Shanghai Pulmonary Hospital, Shanghai, China

Phase 2 Not yet recruiting
34 enrolled
Thoracic

NSCLC

NCT05773092 2025-09-03

A Phase 2 Study of Osimertinib and S-1 in Treatment Resistant EGFR Mutant NSCLC

National Cancer Centre, Singapore

Phase 2 Active not recruiting
30 enrolled
Thoracic

NSCLC

NCT07134413 2025-08-21

QL1706/Bevacizumab ± Chemotherapy in Post-ICI Non-Squamous NSCLC

Guangdong Association of Clinical Trials

Phase 2 Not yet recruiting
77 enrolled
Thoracic

NSCLC

NCT05078931 2025-07-30

A Study to Evaluate Pembrolizumab Plus Lenvatinib in PD-L1 Positive TKI Resistant NSCLC Patients

Shanghai Chest Hospital

Phase 2 Active not recruiting
35 enrolled
Thoracic

NSCLC

NCT07089199 2025-07-28

TitAN

Qilu Hospital of Shandong University

Phase 2 Not yet recruiting
34 enrolled
Thoracic

NSCLC

NCT06864624 2025-07-25

WU-KONG20

Tang-Du Hospital

Phase 2 Recruiting
27 enrolled
Thoracic

NSCLC

NCT07085182 2025-07-25

Tislelizumab Combined With sCRT in Stage IIIB/C-IV Non-Squamous Non-Small Cell Lung Cancer:A Prospective, Single-Arm, Phase II Study

Zibo Municipal Hospital

Phase 2 Recruiting
20 enrolled
Thoracic

NSCLC

NCT07086326 2025-07-25

NEOINSPIRE

Peking University People's Hospital

Phase 2 Not yet recruiting
164 enrolled
Thoracic

NSCLC

NCT02284308 2025-07-04

ELDAPT

Maastricht Radiation Oncology

Active not recruiting
180 enrolled
Thoracic

NSCLC

NCT06754644 2025-06-10

A Study to Evaluate Efficacy, and Safety of QL2107 Plus Chemo and Compare With Keytruda in Participants With IV nqNSCLC

Qilu Pharmaceutical Co., Ltd.

Phase 3 Recruiting
808 enrolled
Thoracic

NSCLC

NCT04820023 2025-06-06

Phase 1/2 Study of BBT-176 in Advanced NSCLC With Progression After EGFR TKI Treatment

Bridge Biotherapeutics, Inc.

Phase 1/2 Terminated
45 enrolled 19 charts
Thoracic

NSCLC

NCT05994131 2025-04-30

IN10018 Combination Therapy in Advanced EGFR Mutation-positive NSCLC

InxMed (Shanghai) Co., Ltd.

Phase 1/2 Recruiting
110 enrolled
Thoracic

NSCLC

NCT06944470 2025-04-25

JS207 Combined With Chemotherapy in Subjects With Stage II-III NSCLC

Shanghai Junshi Bioscience Co., Ltd.

Phase 2 Not yet recruiting
76 enrolled
Thoracic

NSCLC

NCT02973763 2025-04-03

Safety, Tolerability, Pharmacokinetics and Anti-tumour Activity of Alflutinib in Advanced Non Small Cell Lung Cancer

Allist Pharmaceuticals, Inc.

Phase 1 Terminated
14 enrolled
Thoracic

NSCLC

NCT06457789 2025-04-02

iRelate

Amsterdam UMC, location VUmc

Phase NA Recruiting
34 enrolled
Thoracic

NSCLC

NCT04958967 2025-03-14

Phase Ib Study of FURMONERTINIB in Patients with NSCLC Having Exon 20 Insertion Mutation

Allist Pharmaceuticals, Inc.

Phase 1 Withdrawn
Thoracic

NSCLC

NCT05058560 2025-03-13

Tislelizumab in Addition to BACE in Patients with NSCLC

The First Affiliated Hospital of Zhengzhou University

Phase 2 Completed
30 enrolled
Thoracic

NSCLC

NCT06714708 2025-02-10

Low Dose Radiotherapy Combined With Sintilimab and Chemotherapy as Neoadjuvant Therapy for Stage II-III NSCLC

Anhui Provincial Cancer Hospital

Phase 2 Recruiting
86 enrolled
Thoracic

NSCLC

NCT06672068 2024-12-30

A Study of TY-9591 With Chemotherapy as 1st Line Treatment in Patients With Mutated Epidermal Growth Factor Receptor NSCLC

TYK Medicines, Inc

Phase 2 Not yet recruiting
60 enrolled
Thoracic

NSCLC

NCT06532591 2024-12-20

Neoadjuvant/Adjuvant Cadonilimab Plus Chemotherapy in Patients With Resectable PD-L1 Negative NSCLC

Sichuan Cancer Hospital and Research Institute

Phase 2 Recruiting
20 enrolled
Thoracic

NSCLC

NCT06739031 2024-12-18

Clinical Trial to Evaluate the Efficacy and Safety of Pulsed Electric Field Ablation Devices in the Treatment of Lung Tumors

Energenx Medical LTD.

Phase NA Not yet recruiting
126 enrolled
Thoracic

NSCLC

NCT06735508 2024-12-16

MRNA Neoantigen Vaccine in Non-Small Cell Lung Cancer

Guangdong Provincial People's Hospital

Phase EARLY_PHASE1 Not yet recruiting
40 enrolled
Thoracic

NSCLC

Data powered by HemOnc (CC BY 4.0) Colophon âš¡