Clinical Trials

Phase 1 Active not recruiting

Carcinoma, Renal Cell, Kidney Failure, Chronic, Renal Insufficiency

NCT03101995 2025-05-28

Assessment of Gemcitabine as Chemoradiotherapy in Patients With Locally Advanced Carcinoma of Cervix and Renal Disease

Phase 2 Recruiting

18 enrolled

Gynecologic

Uterine Cervical Neoplasms, Renal Insufficiency

NCT04398745 2025-05-23

DREAMM12

36 enrolled

GenitourinaryPlasma cell

Kidney Failure, Chronic, Multiple Myeloma, Renal Insufficiency

NCT03098589 2025-03-30

Revlimid® Capsules Drug Use-results Surveillance (Relapsed or Refractory ATLL)

Head & NeckLymphoidOther hematologic neoplasm

1,149 enrolled

Sleepiness, Arrhythmias, Cardiac, Cataract, Confusion, Coronary Artery Disease, Digestive System Diseases, Dizziness, Fatigue, Heart Failure, Hemorrhage, Hypersensitivity, Hypotension, Orthostatic, Hypothyroidism, Infections, Lymphoma, Peripheral Nervous System Diseases, Seizures, Thromboembolism, Tumor Lysis Syndrome, Neoplasms, Second Primary, Lung Diseases, Interstitial, Renal Insufficiency, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Teratogenesis

NCT06337942 2025-02-12

Deceased Donor Bladder or Combined Kidney-bladder Transplantation: a Phase 0 First-in-human Study

Phase NA Recruiting

5 enrolled

BreastGastrointestinalThoracic

Urinary Bladder Diseases, Urinary Bladder Neoplasms, Urinary Bladder, Neurogenic, Renal Insufficiency

NCT06711939 2024-12-02

VCV

Not yet recruiting

515 enrolled

Breast Neoplasms, Colonic Neoplasms, Infections, Lung Neoplasms, Pneumonia, Stomach Neoplasms, Renal Insufficiency

NCT05797649 2024-11-13

Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study)

Recruiting

120 enrolled

Thoracic

Edema, Fibrosis, Heart Failure, Infections, Neoplasms, Pleural Effusion, Tuberculosis, Hypoalbuminemia, Renal Insufficiency

NCT02301117 2024-09-05

A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment

43 enrolled

Carcinoma, Renal Cell, Kidney Diseases, Kidney Neoplasms, Urologic Diseases, Renal Insufficiency

NCT03814005 2024-09-05

A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

MyeloidOther hematologic neoplasm

17 enrolled 33 charts

Liver Diseases, Myelodysplastic Syndromes, Neoplasms, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Renal Insufficiency

NCT00113113 2024-08-02

Study of Rubitecan in Cancer Patients With Renal or Hepatic Dysfunction

54 enrolled

Liver Diseases, Neoplasms, Renal Insufficiency

NCT04352205 2024-07-01

Daratumumab-Based Therapy for the Treatment of Newly Diagnosed Multiple Myeloma With Kidney Failure

Phase 2 Terminated

17 enrolled

Phase NA Not yet recruiting

Multiple Myeloma, Renal Insufficiency

NCT04827290 2024-04-04

CKD AGE

66 enrolled

GenitourinaryLymphoid

Feeding Behavior, Kidney Failure, Chronic, Lymphoma, Follicular, Renal Insufficiency, Chronic, Renal Insufficiency

NCT04574050 2024-03-19

SELF-BREATHE RCT for Chronic Breathlessness

Phase NA Completed

52 enrolled

Classical hematologyOther

Anemia, Sickle Cell, Asthma, Cystic Fibrosis, Dyspnea, Neoplasms, Liver Failure, Lung Diseases, Interstitial, Pulmonary Disease, Chronic Obstructive, Renal Insufficiency

NCT04594161 2024-02-28

STONE

Phase NA Completed

204 enrolled

Bites and Stings, Calculi, Hydronephrosis, Infections, Kidney Calculi, Kidney Diseases, Neoplasm Metastasis, Pyelonephritis, Ureteral Obstruction, Urinary Calculi, Urologic Diseases, Renal Insufficiency, Urolithiasis, Pyonephrosis, Ureterolithiasis, Nephrolithiasis, Acute Kidney Injury

NCT05701735 2024-02-23

CECIL

Phase NA Unknown

45 enrolled

Gynecologic

Uterine Cervical Neoplasms, Renal Insufficiency

NCT02571036 2023-12-13

A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies

CNSDermatologicGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmSarcomaThoracic

282 enrolled

Mast Cell Activation Disorders, Carcinoma, Non-Small-Cell Lung, Glioma, Leukemia, Mast-Cell, Melanoma, Neoplasms, Germ Cell and Embryonal, Penile Neoplasms, Sarcoma, Mastocytosis, Systemic, Gastrointestinal Stromal Tumors, Renal Insufficiency

NCT02303015 2023-11-21

Toxicity Attributed to Genetic Polymorphisms in Testicular Germ Cell Tumor Survivors

430 enrolled

Cardiovascular Diseases, Neoplasms, Germ Cell and Embryonal, Renal Insufficiency

NCT03234335 2023-05-06

IRMYG

50 enrolled

Multiple Myeloma, Renal Insufficiency

NCT01575925 2022-11-04

POM Renal

25 enrolled

Multiple Myeloma, Renal Insufficiency

NCT01429038 2022-06-14

Mesenchymal Stem Cells After Renal or Liver Transplantation

Phase 1/2 Completed

40 enrolled

Fibrosis, Kidney Diseases, Liver Diseases, Neoplasms, Liver Failure, Liver Failure, Acute, Renal Insufficiency

NCT02921802 2022-06-14

A Study of Special Use Results Surveillance of Revlimid 5mg Capsules

Classical hematologyMyeloidOtherPlasma cell

4,626 enrolled

Arrhythmias, Cardiac, Constipation, Diarrhea, Heart Failure, Hemorrhage, Hypersensitivity, Infections, Multiple Myeloma, Myelodysplastic Syndromes, Myocardial Infarction, Neutropenia, Peripheral Nervous System Diseases, Thrombocytopenia, Tumor Lysis Syndrome, Lung Diseases, Interstitial, Renal Insufficiency, Venous Thromboembolism, Teratogenesis

NCT02922543 2022-06-14

A Safety and Efficacy Study of Revlimid® 5 mg Capsules in Patients With Relapsed or Refractory Multiple Myeloma Who Have Received Long-term Treatment With it Under the Actual Condition of Use

Classical hematologyOtherPlasma cell

361 enrolled

Arrhythmias, Cardiac, Constipation, Diarrhea, Heart Failure, Hemorrhage, Hypersensitivity, Infections, Multiple Myeloma, Myocardial Infarction, Neutropenia, Peripheral Nervous System Diseases, Thrombocytopenia, Tumor Lysis Syndrome, Lung Diseases, Interstitial, Renal Insufficiency, Venous Thromboembolism, Teratogenesis

NCT00634504 2022-06-06

LVPK

LymphoidOther hematologic neoplasmSarcoma

20 enrolled 9 charts

Leukemia, Lymphoma, Osteosarcoma, Renal Insufficiency

NCT05147493 2022-03-29

A Phase 2 Study of Isatuximab in Combination With Bortezomib, Cyclophosphamide and Dexamethasone Followed by Isatuximab and Lenalidomide Maintenance in Newly Diagnosed Patients With Multiple Myeloma and Severe Renal Impairment

Phase 2 Unknown

51 enrolled

Blood Protein Disorders, Hematologic Diseases, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Paraproteinemias, Renal Insufficiency, Neoplasms, Plasma Cell

NCT05298683 2022-03-28

A Phase 2 Study of Isatuximab in Combination With Pomalidomide and Dexamethasone in MM Patients Who Received One Prior Line of Therapy Containing Lenalidomide and a Proteasome Inhibitor

Phase 2 Unknown

108 enrolled

Blood Protein Disorders, Hematologic Diseases, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Paraproteinemias, Renal Insufficiency, Neoplasms, Plasma Cell

NCT02424851 2022-01-27

OPTIMAL

Phase 2 Completed

31 enrolled 13 charts

Multiple Myeloma, Renal Insufficiency, Chronic, Renal Insufficiency, Neoplasms, Plasma Cell

NCT02045017 2021-08-27

Efficacy and Safety of Pomalidomide and Dexamethasone in RRMM Patients With Renal Insufficiency

Phase 2 Completed

81 enrolled

Multiple Myeloma, Renal Insufficiency

NCT02668250 2021-08-26

OPTI-AGED

Phase NA Completed

2,495 enrolled

Alcoholism, Arrhythmias, Cardiac, Dementia, Diabetes Mellitus, Heart Failure, Ischemia, Neoplasms, Respiratory Insufficiency, Peripheral Vascular Diseases, Stroke, Pulmonary Disease, Chronic Obstructive, Renal Insufficiency

NCT04941625 2021-06-28

Risk of Acute Kidney Injury in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy

Unknown

150 enrolled

Renal Insufficiency, Acute Kidney Injury

NCT03172884 2021-04-28

Study of Copanlisib in Hepatic or Renal Impairment

30 enrolled 20 charts

Hepatic Insufficiency, Renal Insufficiency

NCT00854139 2020-03-04

Combined Bone Marrow Transplantation (BMT) and Renal Transplant for Multiple Myeloma (MM) With End Stage Renal Disease (ESRD)

Other hematologic neoplasm

10 enrolled

GenitourinaryPlasma cell

Kidney Failure, Chronic, Multiple Myeloma, Renal Insufficiency

NCT02679131 2019-11-20

To Evaluate Safety and Pharmacokinetics of Belinostat in Patients Who Have Mild, Moderate and Severe Renal Impairment.

Phase 1 Terminated

18 enrolled

Recurrence, Hematologic Neoplasms, Renal Insufficiency

NCT00652626 2019-11-19

RENAL